北陸先端科学技術大学院大学

mark Original papers

2016

73. Dureamae I, Nishida M, Nakaji-Hirabayashi T, Matsumura K, Kitano H. Biodegradable shape memory polymers functionalized with anti-biofouling interpenetrating polymer networks. J Mater Chem B, in press.
72. Ahmed S, Fujita S, Matsumura K. Enhanced Protein Internalization and Efficient Endosomal Escape Using Polyampholyte-Modified Liposomes and Freeze Concentration. Nanoscale, in press. (Selected as a Journal Back Cover)
71. Ota A, Matsumura K, Lee JJ, Sumi S, Hyon SH. StemCell KeepTM is effective for cryopreservation of human embryonic stem cells by vitrification. Cell Transplant, in press.
70. Matsumura K, Kawamoto K, Takeuchi M, Yoshimura S, Tanaka D, Hyon SH. Cryopreservation of a Two-Dimensional Monolayer Using a Slow Vitrification Method with Polyampholyte to Inhibit Ice Crystal Formation. ACS Biomater Sci Eng, 2, 1023-1029, (2016)
69. Chimpibul W, Nagashima T, Hayashi F, Nakajima N, Hyon SH, Matsumura K. Dextran Oxidized by a Malaprade Reaction Shows Main Chain Scission Through a Maillard Reaction Triggered by Schiff Base Formation Between Aldehydes and Amines. J Polym Sci Part A. Polym Chem, 54, 2254-2260, (2016).
68. Rajan R, Hayashi F, Nagashima T, Matsumura K, Toward a Molecular Understanding of the Mechanism of Cryopreservation by Polyampholytes: Cell Membrane Interactions and Hydrophobicity. Biomacromolecules, 17, 1882-1893, (2016)
67. Jain M, Matsumura K, Polyampholyte- and nanosilicate-based soft bionanocomposites with tailorable mechanical and cell adhesion properties. J Biomed Mater Res A, 104A, 1379-1386, (2016).
66. 松村和明 新規凍結保護物質の合成とその応用 低温生物工学会誌、62, 11-15, (2016)

2015

65. Uemura M, Ishiguro H, Matsumura K. Effect of Carboxylated Poly-L-lysine on Morphological Change of Adherent Neuron-like Cells after Extracellular-freezing and Thawing. Cryobiol Cryotechnol, 61, 125-129, (2015)
64. Rajan R, Matsumura K. A zwitterionic polymer as a novel inhibitor of protein aggregation. J Mater Chem B, 3, 5683-5689, (2015) (Selected as a Journal Cover)
63. Takahashi M, Mohan P, Nakade A, Higashimine K, Mott D, Hamada T, Matsumura K, Taguchi T, Maenosono S. Ag/FeCo/Ag Core/Shell/Shell Magnetic Nanoparticles with Plasmonic Imaging Capability. Langmuir, 31,2228-2236, (2015).

2014

62. Rajan R, Matsumura K. Preparation of novel synthetic cryoprotectants. Cryobiol Cryotechnol, 60, 99-103, (2014).
61. Vorontsov DA, Sazaki G, Hyon SH, Matsumura K, Furukawa Y, Antifreeze Effect of Carboxylated ε-Poly-l-lysine on the Growth Kinetics of Ice Crystals, J Phys Chem B, 118, 10240-10249, (2014).
60. Matsumura K, Nakajima N, Sugai H, Hyon SH, Self-degradation of tissue adhesive based on oxidized dextran and poly-L-lysine, Carbohydr Polym, 113, 32-38, (2014).
59. Ahmed S, Hayashi F, Nagashima T, Matsumura K, Protein Cytoplasmic Delivery using Polyampholyte Nanoparticles and Freeze Concentration. Biomaterials, 36, 6508-6518, (2014).
58. Shibao Y, Fujiwara K, Kawasaki Y, Matsumura K, Hyon SH, Ito J, Kashiwazaki N. The effect of a novel cryoprotective agent, carboxylated ε-poly-l-lysine, on the developmental ability of re-vitrified mouse embryos at the pronuclear stage. Cryobiology, 68, 200-204, (2014).
57. Suvannasara O, Tateyama S, Miyasato A, Matsumura K, Shimoda T, Ito T, Yamagata Y, Fujita T, Takaya N, Kaneko T. Biobased polyimides from 4-Aminocinnamic acid photodimer. Macromolecules, 47, 1586-1593, (2014).
56. Hyon SH, Nakajima N, Sugai H, Matsumura K, Low cytotoxic tissue adhesive based on oxidized dextran and epsilonpoly-L-lysine, J Biomed Mater Res A, 102A, 2511-2520, (2014).
55. Matsumura K, Kim HH, Hyon SH, Hypothermicpreservation of Mouse Induced Pluripotent Stem Cells by Polyampholytes, Curr Nanosci, 10, 222-226, (2014).
54. Jain M, Rajan R, Hyon SH, Matsumura K, Hydrogelation of dextran-based polyampholytes with cryoprotective properties via click chemistry. Biomater Sci, 2, 308-317(2014) (selected as a Journal Cover)

2013

53. Watanabe H, Kohaya N, Kamoshita M, Fujikawa K, Matsumura K, Hyon SH, Ito J, Kashiwazaki N. Efficient production of live offspring from mouse oocytes vitrified with a novel cryoprotective agent, carboxylated ε-poly-L-lysine. PLoS One 8 (12), e83613 (2013)
52. Matsumura K. Cryoprotective polyampholytes hydrogel. Cryobiol Cryotechnol 59, 111-115 (2013)
51. Maehara M, Sato M, Watanabe M, Matsunari H, Kokubo M, Kanai T, Sato M, Matsumura K, Hyon SH, Yokoyama M, Mochida J, Nagashima H. Development of a novel vitrification method for chondrocyte sheets. BMC Biotechnology, 2013, 13, 58.
50. Jin OS, Lee JH, Shin YC, Lee EJ, Lee JJ, Matsumura K, Hyon SH, Han DW. Cryoprotection of fibroblasts by carboxylated poly-L-lysine upon repeated freeze/thaw cycles. Cryoletters, 34, 396-403, 2013.
49. Rajan R, Jain M, Matsumura K. Cryoprotective properties of completely synthetic polyampholytes via reversible addition-fragmentation chain transfer (RAFT) polymerization and the effects of hydrophobicity. J. Biomater. Sci. Polym. Ed. 24, 1767-1780 (2013)
48. Matsumura K, Hayashi F, Nagashima T, Hyon SH. Cryoprotective properties of polyampholytes. Cryobiol Cryotechnol. 59, 23-28, (2013).
47. Matsumura K, Hayashi F, Nagashima T, Hyon SH. Long-term cryopreservation of human mesenchymal stem cells using carboxylated poly-L-lysine without the addition of proteins or dimethyl sulfoxide. J. Biomater. Sci. Polym. Ed. 24, 1484-1497, (2013).

2012

46. Vrana N, Matsumura K, Hyon SH, Geever L, Kennedy J, Lyons J, Higginbotham C, Cahill P, McGuinness G: “Cell Encapsulation and Cryostorage in PVA/Gelatin Cryogels: Incorporation of Carboxylated ε-Poly -L-Lysine as Cryoprotectant” J Tissue Eng Regen Med 6, 280-290 (2012)
45. Kanamune J, Kina T, Iwanaga Y, Noguchi H, Matsumura K, Hyon SH. Attenuation of murine GVHD by a tea polyphenol. Cell Transplant 21, 909-918 (2012)

2011

44. Matsumura K, Bae JY, Kim HH, Hyon SH. Effective vitrification of human induced pluripotent stem cells using carboxylated ε-poly-L-lysine. Cryobiology, 63, 76-83 (2011).
43. Inui H, Mizuno J, Hyon SH, Matsumura K, Kikuchi E, Noguchi K, Tanji Y, Akaishi K, Anzai K, Maruyama Y. Development of a Low Toxicity and Completely Serum-Free Vitrification System Combining a Cryo-Nano-Hole Vitrification Container with Antifreeze Polyamino-acid (Carboxylated Poly-L-Lysine) for assisted reproductive technology (ART). J Reprod Engineer. 14, 19-28, 2011.
42. Nakamura J, Nakajima N, Matsumura K, Hyon SH: “In vivo cancer targeting of water-soluble taxol by folic acid immobilization” J Nanomedic Nanotechnol, 2 (1), 1000106, (2011)
41. Kobayashi M, Matsumura K, Hyon SH. “A preliminary in vivo study of artificial meniscus using the uniaxial oriented reinforced compressive polyvinyl alcohol-hydrogel ( PVA-H )” Trends in Biomate Art Organs 25(3), 107-111 (2011).
40. Kakuta Y, Okumi M, Isaka Y, Tsutahara K, Abe T, Yazawa K, Ichimaru N, Matsumura K, Hyon SH, Takahara S, Nonomura N. “Epigallocatechin-3-gallate protects kidneys from ischemia reperfusion injury by HO-1 upregulation and inhibition of macrophage infiltration” Transplantation International 24(5), 514-522 (2011)
39. Yanagi S, Matsumura K, Marui A, Morishima M, Hyon S-H, Ikeda T, Sakata R. “Oral pretreatment with an appropriate dose of a green tea polyphenol facilitates cardioprotection against ischemia-reperfusion injury in an isolated rat heart model” J Thorac Cardiov Sur 141; 511-517 (2011).

2010

38. Matsumura K, Bae JY, Hyon SH. “Large scale vitrification for the preservation of human induced pluripotent stem (iPS) cells using carboxylated poly-L-lysine.” Low Temperature Medicine 36(3): 65-68 (2010).
37. Matsumura K, Bae JY, Hyon SH: “ Polyampholytes as cryoprotective agents for mammalian cell cryopreservation” Cell Transplant.19; 691-699 (2010).
36. Nakamura J, Nakajima N, Matsumura K, Hyon S-H. “Water-soluble taxol conjugates with dextran ant targets tumor cells by folic acid immobilization” Anticancer Res 30: 903-909 (2010).
35. Tanaka S, Hayashi T, Tateyama H, Matsumura K, Hyon SH, “Application of the bactericidal activity of epsilon-poly-L lysine to the storage of human platelet concentrates” Transfusion 50: 932-940 (2010).
34. Matsumura K, Hayami T, Hyon SH, Tsutsumi S, “Control of proliferation and differentiation of osteoblasts on apatite coated poly(vinyl alcohol) hydrogel as an artificial articular cartilage material.” J Biomed Mater Res.A 92A: 1225-1232 (2010)
33. Bae JY, Han DW, Matsumura K, Wakitani S, Nawata M, Hyon SH, “Nonfrozen Preservation of Articular Cartilage by Epigallocatechin-3-Gallate Reversibly Regulating Cell Cycle and NF-kappa B Expression” Tissue Eng A 16: 595-603 (2010)
32. Kashiwa K, Kotobuki N, Tadokoro M, Matsumura K, Hyon SH, Yoshiya S, Ohgushi H. “Effects of epigallocatechin-gallate (EGCG) on osteogenic capability of human mesenchymal stem cells (MSCs) after suspension in phosphate buffered saline” Tissue Eng A. 16: 91-100 (2010).

2009

31. Matsumura K, Hyon SH: “Polyampholytes as low toxic efficient cryoprotective agents with antifreeze protein properties” Biomaterials 30: 4842-4849 (2009) .
30. Matsumura K, Takayama H, Bae JY, Kurihara M, Tsutsumi S, Hyon SH.: “Preservation of platelets by adding epigallocatechin-3-O-gallate to platelet concentrates.” Cell Transplant. 18: 521-528 (2009)
29. Bae JY, MatsumuraK, Wakitani S, Kawaguchi A, Tsutsumi S, Hyon SH.: “Beneficial storage effects of epigallocatechin-3-O-gallate on the articular cartilage of rabbit osteochondral allografts.” Cell Transplant 18: 505-512 (2009).
28. Kim HH, Kawazoe T, Matsumura K, Suzuki S, Hyon SH. : “Long-term preservation of rat skin tissue by epigallocatechin-3-O-gallate” Cell Transplant. 18: 513-519 (2009).
27. Bae JY, Kanamune J, Han DW, Matsumura K, Hyon SH.: Reversible regulation of cell cycle-related genes by epigallocatechin gallate for hibernation of neonatal human tarsal fibroblasts. Cell Transplant. 18: 459-469 (2009).

2008

26. Kim HH, Kawazoe T, Han DW, Matsumura K, Suzuki S, Tsutsumi S, Hyon SH.: “Enhanced wound healing by epigallocatechin gallate-incorpolated collagen sponge in diabetic mice.” Wound Repair Regen 16, 714-720 (2008)
25. Matsumura K, Kaihatsu K, Mori S, Cho HH, Kato N, Hyon SH: “Enhanced antitumor activities of (-)-Epigallocatechin-3-O-gallate fatty acid monoester derivatives in vitro and in vivo.” Biochem Biophys Res Commun 377, 1118-1122 (2008).
24. Han DW, Matsumura K, Kim B, Hyon SH: “Time-dependent intracellular trafficking of FITC-conjugated epigallocatechin-3-O-gallate in L-929 cells.” Bioorg Med Chem 16. 9652-9659, (2008).
23. Cho HH, Han DW, Matsumura K, Tsutsumi S, Hyon SH.: ”The behavior of vascular smooth muscle cells and platelets onto epigallocatechin gallate-releasing poly(L-lactide-co-ε-caprolactone) as stent-coating materials.” Biomaterials 29. 884-893, (2008)

2007

22. Matsumura K, Hyon SH, Nakajima N, Tsutsumi S. : ”Effects on gingival cells of hydroxyapatite immobilized on poly(ethylene-co-vinyl alcohol)” J Biomed Mater Res A 82A 288-295, (2007)
21. Kim JY, Kina T, Iwanaga Y, Noguchi H, Matsumura K, Hyon SH.: ”Tea polyphenol inhibits allostimulation in mixed lymphocyte culture” Cell Transplant 16(1), 75-83 (2007)
20. Hayami T, Matsumura K, Kusunoki M, Nishikawa H, Hontsu S. “Imparting cell adhesion to poly(vinyl alcohol) hydrogel by coating with hydroxyapatite thin film” Materials Letters. 61(13), 2667-2670 (2007)
19. Matsumura K, Kim JY, Tsutsumi S, Hyon SH. “Hibernation, reversible cell growth inhibition by epigallocatechin-3-O-gallate” Jounal of Biotechnology, 127(4), 758-764 (2007)
18. Cho HH, Matsumura K, Nakajima N, Han DW, Tsutsumi S, Hyon SH, “Degradation control of collagen by epigallocatechin-3-O-gallate” Key Engineering Mater, 342-343, 781-784, (2007)
17. Watazu A, Li Y, Tsutsumi S, Matsumura K, Saito N., “Selective bone formation on hydroxyapatite-granule-implanted titanium”, Key Engineering Mater, 330-332, 459-462 (2007)
16. Han DW, Cho HH, Jung DY, Lee JJ, Matsumura K, Park JC, Hyon SH, “Vascular smooth muscle cell behaviours onto epigallocatechin-3-O-gallate-blended L-lactide/ε-caprolactone copolymers” Key Engineering Mater, 342-343, 189-192 (2007)

2006

15. Hyon SH, Matsumura K, Kim JY. : The Application of Green Tea Polyphenol to Regenerative Medicine. Biomaterials Research 10(3), 117-124 (2006)
14. Hyon SH, Kim DH, Cui W, Matsumura K, Kim JY, Tsutsumi S. : “Preservation of rat aortic tissue transplant with green tea polyphenols”. Cell Transplant. 15(10):881-883 (2006)
13. Matsumura K, Tsutsumi S, Hyon SH. “Epigallocatechin-3-O-gallate As a Novel Preservation Additive for Tooth Transplantation.” Journal of Oral Tissue Engineering 3(3):125-130.(2006)
12. Han DW, Cho HH, Matsumura K, Park JC, Hyon SH. “Attenuated proliferation and migration of rat aortic smooth muscle cells into epigallocatechin-3-O-gallate-loaded collagen matrices” Biomaterials Research 10(1): 36-42, (2006).

~2004

11. Matsumura K., Hyon S.-H., Nakajima N., Iwata H., Watazu A., Tsutsumi S. “Surface modification of poly(ethylene-co-vinyl alcohol)(EVA) : Hydroxyapatite immobilization and control of periodontal ligament cells differentiation.” Biomaterials 25:4817-4824(2004)
10. 松村和明、玄 丞烋、堤 定美, “人工歯根材料としてのエチレン-ビニルアルコール共重合体へのハイドロキシアパタイトの固定化” 再生歯科医学会誌 2(2):101-107, (2004)
09. 松村和明、玄 丞烋、堤 定美, “ハイドロキシアパタイト固定化エチレン-ビニルアルコール共重合体上での歯根膜細胞培養” 再生歯科医学会誌 2(2):116-123, (2004)
08. Ushio K., Oka M., Hyon S.-H., Hayami T., Yura S., Matsumura K., Toguchida J. Nakamura T., “Attachment of artificial cartilage to underlying bone” J. Biomed Mater Res Part B: Appl Biomater., 68B: 59-68, (2004)
07. Matsumura K., Hyon S.-H., Nakajima N., Peng C., Iwata H., Tsutsumi S. “Adhesion between polylethylene-co-vinyl alcohol (EVA) and titanium”, J. Biomed Mater. Res, 60(2): 309-315(2002)
06. Peng C., Tsutsumi S., Matsumura K., Nakajima N., Hyon S.-H. “Morphologic study and synthesis of type I collagen and fibronectin of human periodontal ligament cells cultured on poly(ethylene-co-vinyl alcohol) (EVA) with collagen immobilization” J. Biomed Mater. Res, 54: 241-246 (2001)
05. Park J.-C., Hwang Y.-S., Lee J.-E., Park K.-D., Matsumura K., Hyon S.-H., Suh H. “Type Ⅰatelocollagen grafting onto ozone-treated polyurethane films: Cell attachment, proliferation, and collagen synthesis” J. Biomed Mater. Res, 52: 669-677 (2000)
04. 彭 春岩, 堤 定美, 松村和明, 中島直喜, 玄 丞烋, “歯根膜を有する人工歯根の開発 第二報コラーゲン固定化エチレンービニルアルコール共重合体(EVA)へのヒト歯根膜由来細胞培養” 歯科材料・器械 19: 464-469 (2000)
03. 松村和明, 玄 丞烋, 中島直喜, 彭 春岩, 岩田博夫, 堤 定美”歯根膜を有する人工歯根の開発 第一報エチレンービニルアルコール共重合体のチタンへの接着と表面処理” 歯科材料・器械 19: 361-366 (2000)
02. Matsumura K., Hyon S.-H., Nakajima N. and Tsutsumi S. “Surface Modification of Poly(ethylene-vinyl alchohol) (EVA). Part Ⅰ. Introduction of Carboxyl Groups and Immobilization of Collagen” J. Biomed. Mater. Res., 50: 512-517(2000)
01. 松村和明, 玄 丞烋, 岡 正典, 牛尾一康, 堤 定美, “犬膝関節軟骨およびPVAハイドロゲル人工関節軟骨のSEMおよびAFM観察” 高分子論文集, 55: 786-790(1998)

mark Reviews and books

09. 松村和明、玄 丞烋. 緑茶カテキンの再生医療への応用, ポリフェノール:機能性成分研究開発の最新動向、監修:波多野力、下田博司、シーエムシー出版、pp240-247. (2016).
08. Kazuaki Matsumura, Robin Rajan, Sana Ahmed, Minkle Jain. Medical Application of Polyampholytes. In Biopolymers for Medical Applications. Ed. Juan M. Ruso, CRC Press, pp 164-181. (2016).
07. Kazuaki Matsumura, Minkle Jain, Rajan Robin, Cell and Materials Interface in Cryobiology and Cryoprotection. In Cell and Material Interface: Advances in Tissue Engineering, Biosensor, Implant, and Imaging Technologies, Ed. Nihal Engin Vrana, CRC Press, pp163-186. (2015)
06. 松村和明:凍結保護作用を持つ高分子の開発とそのバイオメディカル応用、バイオマテリアル-生体材料-, 33-1, pp.21-24, (2015)
05. 松村和明:ゲルテクノロジーハンドブック 第4章 第8節 細胞凍結保護機能を持つ両性電解質ヒドロゲル pp698-702 (2014) NTS
04. 松村和明:再生医療における臨床研究と製品開発 第2章 第2節[4] 細胞の凍結・解凍方法 pp133-137 (2013)技術情報協会
03. 玄 丞烋 、松村和明:不凍ポリアミノ酸を用いたヒトiPS細胞の凍結保存、医学の歩み 238(13) 1212-1214, (2011) 医歯薬出版
02. 松村和明、玄 丞烋 :不凍ポリアミノ酸の再生医療と食品工業への展開 Bio Industry 28(5) 35-42, (2011) シーエムシー出版
01. 松村和明、玄 丞烋:iPS/ES細胞の大規模保存システムの開発。再生医療、9 :3; 349-354. (2010) メディカルレビュー社

mark Conferences

2016

松村和明、Sana Ahmed, 第61回低温生物工学会、6/25-26, 2016, 埼玉
凍結濃縮を利用した細胞質内タンパク質デリバリー
Kazuaki Matsumura, Manato Suzuki, Daisuke Tanaka, Suong-Hyu Hyon, 10th WBC, Montreal, 5/18-22
Tissue-engineered constructs preservation using a novel slow vitrification method with hydrophobically modified polyampholyte to inhibit ice crystallization
Robin Rajan, Sparsh Makhaik, Kazuaki Matsumura, 10th WBC, Montreal, 5/18-22
Zwitterionic polymers and nanogels as new class of protein aggregation inhibitors
Robin Rajan, Kazuaki Matsumura, 10th WBC, Montreal, 5/18-22
Synthetic polymers for cellular cryopreservation: A new and versatile class of cryoprotectants
Minkle Jain, Kazuaki Matsumura, 10th WBC, Montreal, 5/18-22
Soft bionanocmposites based on poly-L-lysine and nanosilicate for tissue engineering applications
Tomoyo Sakaguchi, Shusaku Nagano, Mitsuo Hara, Yoshihiro Kimura, Akinobu Oharuda, Kazuaki Matsumura, 10th WBC, Montreal, 5/18-22
Evaluation of physical property for syndiotactic PVA-H by hot pressing method
Sana Ahmed, Kazuaki Matsumura, 10th WBC, Montreal, 5/18-22
Exploring the intracellular pathways of lysozyme protein using polyampholyte modified liposomes and freeze concentration method
Sana Ahmed, Kazuaki Matsumura, 10th WBC, Montreal, 5/18-22
Effective gene delivery by using freeze concentration method
Monika Patel, Kazuaki Matsumura, 10th WBC, Montreal, 5/18-22
Hierarchical Hydrogel formation through micellization of amphiphilic block polypeptide in aqueous media
Kazuaki Matsumura, 第55回生体医工学会、富山、4/25-27(セッションオーガナイザー、Invited Lecture)
Development of novel cryoprotectants and their application for tissue engineering
Kazuaki Matsumura, Wichchulada Konkumnerd, GRIP2016, 3/4-7, Ishikawa (Invited Lecture)
Biodegradable polysaccharide by Malaprade oxidation for tissue engineering

2015

横倉佑亮、松村和明、第四回日本バイオマテリアル学会北陸若手研究発表会、11/30, 石川
セルロースナノファイバーハイドロゲルの薬物徐放へ向けた生分解特性評価
寺井渉、星島裕子、後藤和馬、松浦宏治、松村和明、第四回日本バイオマテリアル学会北陸若手研究発表会、11/30, 石川
人工軟骨材料としてのPVAナノコンポジットハイドロゲルの開発と機能性評価
万治志、松村和明、木村佳弘、第四回日本バイオマテリアル学会北陸若手研究発表会、11/30, 石川
血管内皮細胞の固定を目的とした変成PVAハイドロゲルの表面改質
鈴木雅、田中大介、松村和明、第四回日本バイオマテリアル学会北陸若手研究発表会、11/30, 石川
疎水基の導入による両性電解質高分子の凍結保護効果の向上
松村和明、第42回日本低温医学会総会、11/26-27, 石川 (Invited Lecture)
Effective Cryopreservation of the Stem Cell for a Regeneration Medicine by using polymeric cryoprotectant
Kazuaki Matsumura, 2015 EU-Japan Workshop on Next-Generation Nanomagnetic Medicine, 11/24-25, Ishikawa (Invited Lecture)
Polymer modification of nanoparticles toward biomedical applications
Sana Ahmed, Kazuaki Matsumura, 2015 EU-Japan Workshop on Next-Generation Nanomagnetic Medicine, 11/24-25, Ishikawa
Deciphering the internalisation and efficient cytoplasmic delivery of lysozyme protein by polyampholyte
modified liposome and freeze concentration
松村和明、第2回低温科学技術交流会、11/17、東京 (Invited Lecture)
高分子凍結保護物質を用いた再生医療用幹細胞の凍結保存
Robin Rajan, Kazuaki Matsumura, 第64回高分子学会北陸支部研究発表会、11/14-15、石川
Synthetic polymers for cellular cryopreservation: A new and versatile class of cryoprotectants
Minkle Jain, Kazuaki Matsumura, 第64回高分子学会北陸支部研究発表会、11/14-15、石川
Shear thinning in situ injectable hydrogel using poly-L-lysine as cryoprotectant and synthetic sillicate for cell delivery purposes.
阪口智世、松村和明、第64回高分子学会北陸支部研究発表会、11/14-15、石川
濃厚ポリビニルアルコール水溶液-ゲル化に影響を与える条件の解析-
鈴木雅、松村和明、平成27年度北陸地区高分子若手研究会、11/13, 石川
疎水化両性電解質高分子の凍結保護能
寺井渉、松村和明、平成27年度北陸地区高分子若手研究会、11/13, 石川
人工軟骨材料としてのPVAナノコンポジットハイドロゲルの開発と機能性評価
横倉佑亮、松村和明、平成27年度北陸地区高分子若手研究会、11/13, 石川
生分解性セルロースナノファイバーハイドロゲルのマラプラード酸化による分解特性評価
万治志、松村和明、平成27年度北陸地区高分子若手研究会、11/13, 石川
細胞接着性の向上を目的とした変成PVAハイドロゲルの表面改質
Wichchulada Konkumnerd, Kazuaki Matsumura, 平成27年度北陸地区高分子若手研究会, 11/13, 石川
Degradation Control of Polysaccharide by Malaprade Oxidation for Tissue Engineering
Monika Patel, Kazuaki Matsumura, 平成27年度北陸地区高分子若手研究会, 11/13, 石川
Synthesis of Nano-assembly of Synthetic Polypeptides and Their Study for Cell-engineering Application
Sana Ahmed, Kazuaki Matsumura, 平成27年度北陸地区高分子若手研究会, 11/13, 石川
Enhancing the Endosomal Escape of Protein by Polyampholyte Modified Liposomes Using Freeze Concentration Strategy
Sparsh Makhaik, Kazuaki Matsumura, 平成27年度北陸地区高分子若手研究会, 11/13, 石川
The Synthesis of Sulfobetaine Polymers Using RAFT Polymeristaion and Study Their Stucture-property Relationship
Monika PATEL, Kazuaki Matsumura, SAST2015, 11/10-12, Ishikawa
Nano-Assembly of Precisely-Synthesized Amphiphilic Polypeptides and Cell-Engineering Application
Robin Rajan, Kazuaki Matsumura, SAST2015, 11/10-12, Ishikawa
A zwitterionic polymer for the effective suppression of protein aggregation
Nozomi Manji, Kazuaki Matsumura, SAST2015, 11/10-12, Ishikawa
The development of carbonyl modified poly(vinyl alcohol) (PVA) to modify surface with endothelial cell
Yuusuke Yokokura, Kazuaki Matsumura, SAST2015, 11/10-12, Ishikawa
Basic study of degradation of cellulose nanofibers to apply for drug delivery system
鈴木雅、田中大介、松村和明、第37回日本バイオマテリアル学会、11/9-10, 京都
疎水化両性電解質高分子の凍結保護効果
横倉佑亮、松村和明、第37回日本バイオマテリアル学会、11/9-10, 京都
生分解性セルロースナノファイバーハイドロゲルの分解特性評価
松村和明、河本慶子、田中大介、Cryopreservation Conference2015、10/28-29, 岡崎
両性電解質高分子を利用した緩慢およびガラス化凍結保存
Sana Ahmed, Kazuaki Matsumura, APME2015, 10/18-22, Yokohama
Investigating the uptake and intracellular delivery of protein by using polyampholyte modified liposome based carrier system and freeze concentration mechanism
Sana Ahmed, Kazuaki Matsumura, APME2015, 10/18-22, Yokohama
Fundamental investigation of freeze concentration strategy in delivery of protein by using polyampholyte nanoparticles
Sparsh Makhaik, Robin Rajan, Kazuaki Matsumura, APME2015, 10/18-22, Yokohama
The study of structure and property relationship of sulfobetaine polymers
阪口智世、森田有亮、松村和明、日本機械学会第26回バイオフロンティア講演会、10/2-3, 福岡
濃厚水溶液を用いた新規作製法によるポリビニルアルコールハイドロゲル(PVA-H)の機械的特性評価
阪口智世、永野修作、原光生、木村佳弘、小原田明信、松村和明、第64回高分子討論会、9/15-17, 仙台
圧縮法によるポリビニルアルコールハイドロゲルの結晶構造制御によるゲル化
万治志、松村和明、木村佳弘、第64回高分子討論会、9/15-17, 仙台
血管内皮細胞の付着を目的とした変成PVAハイドロゲルの開発
寺井 渉、星島 裕子、後藤 和馬、松浦 宏治、松村 和明、第64回高分子討論会、9/15-17, 仙台
人工軟骨材料としてのPVAナノコンポジットハイドロゲルの開発と機能性評価
Wichchulada Konkumnerd , Tadashi Nakaji-Hirabayashi, Suong-Hyu Hyon, Kazuaki Matsumura,第64回高分子討論会、9/15-17, 仙台
Degradation control of polysaccharide by Malaprade oxidation for tissue engineering
Kazuaki Matsumura, Keiko Kawamoto, Suong-Hyu Hyon, ESB2015, 8/30-9/3, Poland
2D Cell Monolayer and 3D Cell Construct Cryopreservation by Slow Vitrification
Minkle Jain, Kazuaki Matsumura, ESB2015, 8/30-9/3, Poland
Shear- thinning Soft Bionanocomposites Based on Laponite and Poly-L-lysine for Cell Delivery Purposes
Minkle Jain, Kazuaki Matsumura, ESB2015, 8/30-9/3, Poland
Poly-L-lysine Based Covalently Crosslinked Bionanocomposites with Controlled Drug Release and Cell Adhesion Properties
Robin Rajan, Kazuaki Matsumura, ESB2015, 8/30-9/3, Poland
Development of Structurally Analogous Cryoprotective Synthetic Polyampholytes and Elucidation of Mechanism
Robin Rajan, Kazuaki Matsumura, ESB2015, 8/30-9/3, Poland
Zwitterionic Polyampholyte as a novel inhibitor of lysozyme aggregation
松村和明、第60回低温生物工学会、5/30-31, 東京 (研究奨励賞受賞講演)
新規凍結保護物質の合成とその応用
鈴木雅、田中大介、松村和明、第60回低温生物工学会、5/30-31, 東京
新規ガラス状態安定化高分子の開発
中路正、藤本くる美、北野博巳、松村和明、第64回高分子学会年次大会、5/27-29, 札幌
移植細胞の分化を制御できるハイドロゲルの創製とパーキンソン病治療への適応
横倉佑亮、松村和明、第64回高分子学会年次大会、5/27-29, 札幌
生分解性セルロースナノファイバーのドラッグデリバリーシステム応用への基礎検討
万治志、木村佳弘、松村和明、第64回高分子学会年次大会、5/27-29, 札幌
カルボニル基を有する変成PVAを混合したPVAハイドロゲルの表面改質
寺井 渉、松村 和明、第64回高分子学会年次大会、5/27-29, 札幌
PVAナノクレイコンポジットハイドロゲルの開発と機能性評価
Kazuaki Matsumura, JAIST JAPAN-INDIA symposium on materials science 2015. 3/2, Nomi, (Invited Lecture)
Protein Cytoplasmic Delivery by Freeze Concentration
Kazuaki Matsumura, 2015 JAIST-IISc Matching seminar, 2/27, Bangalore, India, (Invited Lecture)
Biomaterials in Tissue Engineering and Cryopreservation

2014

松村和明 MRS-J2014年次大会、12/10、 横浜
ホットプレスによる高濃度PVA水溶液からのPVAハイドロゲルの形成
Minkle Jain, Kazuaki Matsumura, IPC2014, 12/2-5, Tsukuba
Self Healing Soft Bio-Nanacomposite Hydrogel Based on Laponite and Cryoprotective Polyampholyte
Robin Rajan, Kazuaki Matsumura, IPC2014, 12/2-5, Tsukuba
Disparate membrane interaction of structurally analogous synthetic polyampholytes with cryoprotective properties
Tomoyo Sakaguchi, Shusaku Nagano, Mitsuo Hara, Suong-Hyu Hyon, Kazuaki Matsumura, IPC2014, 12/2-5, Tsukuba
Effect of solvents on hot-pressing hydrogelation process of poly (vinyl alcohol)
Yuki Hirano, Takashi Hayami, Sachi Yoshikawa, Ryoichi Shirosaki, Koji Morimoto, Kazuaki Matsumura, IPC2014, 12/2-5, Tsukuba
Surface modification of poly(vinyl alcohol) hydrogel by graft polymerization of betaine polymer
松村和明、第36回日本バイオマテリアル学会11/17-18, 東京
凍結保護作用を持つ高分子の開発とそのバイオメディカル応用
Minkle Jain, Kazuaki Matsumura, 第36回日本バイオマテリアル学会11/17-18, 東京
Clay and Poly-L-lysine based soft bio nanocomposites with cryoprotective and thixotropic properties
Robin Rajan, Kazuaki Matsumura, 第36回日本バイオマテリアル学会11/17-18, 東京
Interaction of polyampholytes with cell membrane and its effect on cryopreservation properties
平野由起、森本浩嗣、吉川祥、白崎諒一、速水 尚、松村和明、第36回日本バイオマテリアル学会11/17-18, 東京
人工関節軟骨用ポリビニルアルコールハイドロゲルへのベタインポリマーのグラフト重合
Sana Ahmed, Kazuaki Matsumura, IRAGO Conference, 11/6-7, Tsukuba
Development of enhanced protein delivery by polyampholyte nanoparticles using freeze concentration
松村和明、河本慶子、田中大介、藤島政博、Cryopreservation Conference 2014 10/23-24, 岡崎
両性電解質高分子の凍結保護効果の検討とゾウリムシ凍結の試み
Kazuaki Matsumura, Robin Rajan. Cryopreservation Conference 2014 10/23-24, 岡崎
両性電解質高分子の凍結保護効果のメカニズム
Robin Rajan, Kazuaki Matsumura, 第三回日本バイオマテリアル学会北陸若手研究発表会, 10/14, 福井
Synthesis of novel polyampholytes with disparate cryoprotective properties and elucidation of mechanism of cryopreservation
Minkle Jain, Kazuaki Matsumura, 第三回日本バイオマテリアル学会北陸若手研究発表会, 10/14, 福井
Soft thixotropic bio nanocomposites based on laponite and polyampholyte with tunable mechanical properties
Sana Ahmed, Kazuaki Matsumura, 第三回日本バイオマテリアル学会北陸若手研究発表会, 10/14, 福井
Cytoplasmic delivery of protein mediated by polyampholyte nanoparticle using freeze concentration
平野由起、松村和明、第三回日本バイオマテリアル学会北陸若手研究発表会, 10/14, 福井
ベタインポリマーのグラフト重合によるポリビニルアルコールハイドロゲルの表面改質
Minkle Jain, Kazuaki Matsumura, IUMRS-ICA, 8/25-29, Fukuoka
Soft bio nanocomposites based on laponite with cryoprotective and thixotropic properties
Robin Rajan, Kazuaki Matsumura, IUMRS-ICA, 8/25-29, Fukuoka
Novel polymeric cryoprotectant and its mode of action on cells
Tomoyo Sakaguchi, Shusaku Nagano, Mitsuo Hara, Suong-Hyu Hyon, Kazuaki Matsumura, IUMRS-ICA, 8/25-29, Fukuoka
Gelation process of poly(vinyl alcohol) concentrated aqueous solution by hot pressing method
松村和明、Wochchulada Konkumnerd、玄 丞烋 、医用高分子研究会, 7/28-29, 東京
セルロースへの生体内分解性付与とその足場材料応用の検討
Robin Rajan, Kazuaki Matsumura, 第59回低温生物工学会, 6/28-29, 福岡
Preparation of novel synthetic cryoprotectants
阪口智世、永野修作、原光生、玄丞烋、松村和明、第63回高分子学会年次大会, 5/28-30, 名古屋
圧縮法によるポリビニルアルコール濃厚水溶液のゲル化過程解析
平野由起、松村和明、第63回高分子学会年次大会, 5/28-30, 名古屋
ポリビニルアルコールハイドロゲルへのベタインポリマーのグラフト重合
Kazuaki Matsumura (Invited Lecture)
International Symposium for Green-Innovation Polymers (GRIP2014), 3/4, Kanazawa, Ishikawa
A Self-degradable Polysaccharide as Biomedical Application
Kazuaki Matsumura (Invited Lecture)
20th ISCB International Conference on Chemistry and Medicinal Plants in Translational Medicine for Healthcare, 1-4 Mar, Delhi India
Biomedical application of oxidized polysaccharide as a self-degradable material
松村和明、サクラン研究会、1/10、能美, (Invited lecture)
多糖類を用いた自己分解性医療材料

2013

Wichchulada Konkumnerd, Kazuaki Matsumura
第二回日本バイオマテリアル学会北陸若手研究発表会 12/16 富山
Degradation control of cellulose scaffold by Malaprade reaction for tissue engineering.
Esha Das, Kazuaki Matsumura
第二回日本バイオマテリアル学会北陸若手研究発表会 12/16 富山
Study of phase separation by thermoresponsive carboxylated poly-L-lysine
Sana Ahmed, Kazuaki Matsumura
第二回日本バイオマテリアル学会北陸若手研究発表会 12/16 富山
Self assembly of Polyampholytes as potential carriers for drug delivery induced by freeze concentration
阪口智世、松村和明
第二回日本バイオマテリアル学会北陸若手研究発表会 12/16 富山
濃厚PVA水溶液のゲル化過程解析
Esha Das, Kazuaki Matsumura
MRS Fall meeting 2013,2013/12/1-6,Boston, USA
Phase separation behavior of carboxylated poly-L-lysine
Sana Ahmed, Kazuaki Matsumura
MRS Fall meeting 2013,2013/12/1-6,Boston, USA
Freezing assisted protein delivery by using polymeric cryoprotectant
Wichchulada Konkumnerd, Suong Hyu Hyon, Kazuaki Matsumura
MRS Fall meeting 2013,2013/12/1-6,Boston, USA
Degradation control of cellulose by Malaprade oxidation for tissue engineering application
Tomoyo Sakaguchi, Suong Hyu Hyon, Kazuaki Matsumura
MRS Fall meeting 2013,2013/12/1-6,Boston, USA
Hydrogel formation from the concentrated aqueous solution of polyvinyl alcohol
松村和明、Sana Ahmed
第35回日本バイオマテリアル学会、2013/11/25-26、東京
凍結濃縮を利用したタンパク質デリバリーの試み
松村和明、Wichchulada Konkumnerd、玄 丞烋
第35回日本バイオマテリアル学会、2013/11/25-26、東京
多糖類の酸化による分解制御とその足場材料への応用
阪口智世、松村和明
第40回日本臨床バイオメカニクス学会、11/22-23、神戸
ポリビニルアルコール濃厚水溶液 -ゲル化の過程と構造の解析-
Tomoyo Sakaguchi, Suong Hyu Hyon, Kazuaki Matsumura
International Symposium on Advanced Materials 2013, 2013/10/17, Ishikawa
Hydrogel formation from the concentrated aqueous solution of polyvinyl alcohol and structural analysis
Esha Das, Kazuaki Matsumura
International Symposium on Advanced Materials 2013, 2013/10/17, Ishikawa
Temperature dependent phase transition of carboxylated poly-L-lysine
Sana Ahmed, Kazuaki Matsumura
International Symposium on Advanced Materials 2013, 2013/10/17, Ishikawa
Polyampholyte nanoparticle based protein delivery enhanced by freezing
Wichchulada Konkumnerd, Suong Hyu Hyon, Kazuaki Matsumura
International Symposium on Advanced Materials 2013, 2013/10/17, Ishikawa
Degradation control of cellulose scaffold by Malaprade oxidation for tissue engineering application
Robin Rajan, Kazuaki Matsumura
International Symposium on Advanced Materials 2013, 2013/10/17, Ishikawa
Cryopreservation of cells using synthetic polymers via living polymerization and the effect of hydrophobicity
Minkle Jain, Suong Hyu Hyon, Kazuaki Matsumura
International Symposium on Advanced Materials 2013, 2013/10/17, Ishikawa
Novel cryoprotective hydrogel of Dextran based polyampholytes via Cu-free Click Chemistry
Kazuaki Matsumura
International Symposium on Advanced Materials 2013, 2013/10/17, Ishikawa, (Invited lecture)
Biomedical application of polyampholytes
Kazuaki Matsumura, Sana Ahmed
International Symposium on Nanomedicine Molecular Science 2013, 2113/10/8-10, Tokyo
Polyampholyte based protein delivery enhanced by freeze concentration
阪口智世、永野修作、原光生、玄丞烋、松村和明
第62回高分子討論会,2013/9/11-13,金沢
ポリビニルアルコール濃厚水溶液のゲル化とその構造解析
Esha DAS、 Kazuaki MATSUMURA
第62回高分子討論会,2013/9/11-13,金沢
Phase separation behavior of carboxylated poly-L-lysine
Wichchulada KONKUMNERD、 Suong-Hyu HYON、Kazuaki MATSUMURA
第62回高分子討論会,2013/9/11-13,金沢
Degradation control of polysaccharides by Malaprade oxidation
Sana AHMED、Kazuaki MATSUMURA
第62回高分子討論会,2013/9/11-13,金沢
Micelles formation of polyampholytes for controlled release
松村和明
日本動物細胞工学会2013年度大会,2013/7/19,福井, (invited lecture)
両性電解質高分子を用いた細胞および細胞構造体の凍結
松村和明
第58回低温生物工学会,2013/6/22,大阪
両性電解質高分子ハイドロゲルによる細胞のカプセル化と凍結
Kazuaki Matsumura
International Workshop on Functional Polymer Surface and Interface, 2013/3/19, Ishikawa, (Invited lecture)
Polymer Cryoprotectants and their Biomedical Applications

2012

Robin Rajan, Kazuaki Matsumura
第一回日本バイオマテリアル学会北陸若手研究発表会 12/25 石川
Cryoprotective property of synthetic polyampholytes with hydrophobic moiety
Minkle Jain, Kazuaki Matsumura
第一回日本バイオマテリアル学会北陸若手研究発表会 12/25 石川
Hydrogelation of Dextran-based polyampholytes via Cu-free click chemistry and their cryoprotective properties
阪口智世、松村和明
第一回日本バイオマテリアル学会北陸若手研究発表会 12/25 石川
ポリビニルアルコール濃厚水溶液のゲル化
Robin Rajan, Kazuaki Matsumura
MRS Fall meeting 2012,2012/11/25,Boston, USA
Systematic development of a synthetic polyampholyte basedcryoprotective agent by Reversible Addition Fragmentation ChainTransfer polymerization
Minkle Jain, Kazuaki Matsumura
MRS Fall meeting 2012,2012/11/25,Boston, USA
Dextran based polyampholyte hydrogel having cryoprotective properties via Click Chemistry
Robin Rajan, Kazuaki Matsumura
第61回高分子討論会,2012/9/19-21,名古屋
Synthetic polyampholytes for cryopreservation
Minkle Jain, Hyon Suong Hyu, Kazuaki Matsumura
第61回高分子討論会,2012/9/19-21,名古屋
Kazuaki Matsumura, Suong Hyu Hyon
3rd Tissue Engineering and Regenerative Medicine International Society World Congress,2012/9/5-8,Vienna
Development of hydrogel with cryoprotective properties using dextran
Cryoprotective cell scaffold for tissue engineering
Kazuaki Matsumura, Fumiaki Hayashi, Toshio Nagashima, Suon-Hyu Hyon
NIAS International Seminar for Cryobiology and Cryotechnology,2012/5/31, Tsukuba (invited lecture)
Cryoprotective properties of polyampholytes

2011

松村和明
平成23年度 日本バイオマテリアル学会北陸若手研究発表会 12/22 福井
両性電解質高分子化合物の細胞凍結保護活性
松村和明,林 文晶,長島敏雄,玄 丞烋
第33回日本バイオマテリアル学会 11/21-22 京都、 細胞凍結保護ポリマーの 凍結挙動
松村和明,林 文晶,長島敏雄,玄 丞烋
第60回高分子学会北陸支部研究発表会 11/19-20 石川、両性電解質高分子の凍結保護特性とその凍結時挙動
Kazuaki Matsumura, and Suong-Hyu Hyon
4th Annual World Congress of Regenerative Medicine & Stem Cell (RMSC-2011) Effective Cryopreservation of the Stem Cell for a Regeneration Medicine. 
松村和明・林文晶、長島敏雄、玄  丞烋
第60回高分子討論会 9/28-30 岡山、 凍結保護能を持つ両性電解質高分子 の凍結時挙動の固体NMRによる解析
Suong-Hyu Hyon, Kazuaki Matsumura
Ice-Binding Protein Conference, 8/3-6, Ontario CANADA, Creation of antifreeze polyaminoacid with cryoprotective function.
松村和 明、林文晶、長島 敏雄、玄 丞烋
低温生物工学会7/7-8 岩手 凍結保護活性を持つカルボキシル化ポリリジ ン溶液の固体NMR測定による凍結時の挙動の評価
Suong-Hyu Hyon, Kazuaki Matsumura
World Biobanking Summit, 6/30-7/1, Hamburg Germany, NOVEL CRYOPROTECTIVE AGENT (CPA) of Stem Cell for Regenerative Medicine

mark Awards

平成20年第35回臓器保存生物医学会 会長賞
平成21年京都大学再生医科学研究所 研究奨励賞(長石賞)
平成22年日本低温医学会 ゴールドメダル賞
平成26年日本バイオマテリアル学会 科学奨励賞
平成27年日本低温生物工学会 科学奨励賞