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マテリアル研究棟MS Building II 6F


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Takayoshi Watanabe Senior Lecturer
School of Materials Science、Bioscience and Biotechnology Area


B.S.from Toho University(2003), M.S.from Toho University(2005), Ph.D from Japan Advanced Institute of Science and Technology(2008)

■Professional Career

Researcher at I.S.T(2008), Researcher at Japan Advanced Institute of Science and Technology(2009)


Chemical Biology, Protein Engineering, Synthetic Organic Chemistry, Biotechnology

■Research Keywords

Non-natural amino acid, Artificial protein, Biopharmaceutical, Antibody, Caged compound


◇Published Papers

  • Statistical description of the denatured structure of a single protein, staphylococcal nuclease, by FRET analysis,Mariko Yamaguchi, Emi Ohta, Takuya Muto, Takayoshi Watanabe, Takahiro Hohsaka, Yoichi Yamazaki, Hironari Kamikubo and Mikio Kataoka,Biophysical Reviews,10,145-152,2017
  • Freezing Assisted Gene Delivery Combined with Polyampholyte Nanocarriers.,Ahmed S, Nakaji-Hirabayashi T, Watanabe T, Hohsaka T, Matsumura K.,ACS Biomater. Sci. Eng.,3,8,1677-1689,2017
  • Site-specific N-terminal Fluorescent Labeling of Unprotected Peptides.,Keisuke Fukunaga, Takayoshi Watanabe, Takahiro Hohsaka,Peptide Science 2015,289-290,2016

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◇Lectures and Presentations

  • Inter- and intramolecular photocrosslink of proteins through incorporation of nonnatural amino acids,Rumi Shiba, Takayoshi Watanabe, Takahiro Hohsaka,The 6th International Symposium on Dynamical Ordering of Biomolecular System for Creation of Integrated Functions.,Shizuoka,January
  • A novel IgG-based fluorescent probe showing increased fluorescence upon binding of antigen,Keisuke Fukunaga・Dian Novitasari・Takayoshi Watanabe・Takahiro Hohsaka,The 6th Official Conference of the International Chemical Biology Society, ICBS2017,Shanghai (China),Oct.17-20th, 2017
  • Position-specific protein PEGylation through incorporation of aromatic amine-containing non-natural amino acid,Takayoshi Watanabe,IISc-JAIST Joint Workshop on Functional Inorganic and Organic Materials,Ishikawa,March, 2016

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■Extramural Activities

◇Academic Society Affiliations

  • Division of Biofunctional Chemistry, The Chemical Society of Japan,Member,2015-
  • The Molecular Biology Society of Japan,Regular Membership,2015-
  • The Japan Society of Drug Delivery System,2012-

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■Academic Awards Received

  • 17th Excellent Paper Award of the Society for Biotechnology,The Society for Biotechnology, Japan,2009