The Phylogenetic Reconstruction from Non-Genomic Data tool allows you to cluster a set of organisms based on their metabolic pathways. You have a choice of selected organisms and metabolic pathways taken from KEGG, three enzyme similarity measures (gene ontology, hierarchical, information content), two clustering methods (UPGMA or neighbor-joining), the choice of full names or KEGG abbreviations, and the value of the α parameter (relative weight of compounds and enzymes in assessing the similarity of enzymatic reactions).
The output is a reconstructed phylogenetic tree for the selected set of organisms, both in Newick format and as a cladogram
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