between Closed inf-TRMs and Closed sup-TRMs
1. DOT6
2. RIM101_GTS1
3. CHA4
4. RTS2
5. MIG1
6. RTG1
7. HAP2_HAP3_HAP5
8. GCR1
9. YJL206C_MCM1
10. FKH1_FKH2_NDD1
11. SUM1_GCN4
12. GAT3_SWI5_YAP5
13. PDR1_FHL1_RAP1
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1. DOT6
Inf-TRM
Module: 1
Regs: DOT6 #Support: 3 Similar_ratio: 1.0
------------------------
0.0368017 YPR032W polarized exocytosis by regulating SNARE function
0.0541316 YHR155W strong similarity to SNF1P-interacting protein SIP3P
0.0573352 YBR156C Mitotic spindle protein involved in chromosome segregation
Sup-TRM
Module: 1
Regs: DOT6 #Support: 5 Similar_ratio: 0.6
------------------------
0.0368017 YPR032W polarized exocytosis by regulating SNARE function
0.0541316 YHR155W strong similarity to SNF1P-interacting protein SIP3P
0.0573352 YBR156C Mitotic spindle protein involved in chromosome segregation
*0.128214 YAR007C "DNA replication factor A, 69 KD subunit"
*0.110768 YAR008W tRNA splicing endonuclease gamma subunit
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2. RIM101_GTS1
Inf-TRM
Module: 2
Regs: RIM101_GTS1 #Support: 4 Similar_ratio: 0.75
------------------------
0.0254554 YAL067C suppressor of sulfoxyde ethionine resistance
0.0533893 YAL065C strong similarity to FLO1P and FLO9P - putative pseudogene
0.0567335 YAL064C-A "strong similarity to FLO1P, FLO5P - putative pseudogene"
*0.324134 YAL068C strong similarity to subtelomeric encoded proteins
Sup-TRM
Module: 3
Regs: RIM101_GTS1 #Support: 5 Similar_ratio: 0.6
------------------------
0.0403895 YAL064C-A "strong similarity to FLO1P, FLO5P - putative pseudogene"
0.041781 YDR282C "similarity to hypothetical protein YDL001w, YFR048w and S.pombe hypothetical protein SPAC12G12.14"
0.0430576 YAL067C suppressor of sulfoxyde ethionine resistance
*0.0968788 YAL065C strong similarity to FLO1P and FLO9P - putative pseudogene
*0.267924 YAL068C strong similarity to subtelomeric encoded proteins
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3. CHA4
Inf-TRM
Module: 3
Regs: CHA4 #Support: 5 Similar_ratio: 0.6
------------------------
0.0400326 YPR140W similarity to human BTHS gene involved in Barth syndrome
0.0414743 YDR057W weak similarity to L.lactis mleR protein
0.0445302 YPR139C "weak similarity to nGAP,H. sapiens nGAP mRNA"
*0.0997692 YGL121C hypothetical protein
*0.126284 YDR056C hypothetical protein
Sup-TRM
Module: 6
Regs: CHA4 #Support: 7 Similar_ratio: 0.57
------------------------
0.0391684 YDR322W "ribosomal protein YmL35 of the large subunit, mitochondrial"
0.04237 YDR057W weak similarity to L.lactis mleR protein
0.04374 YPR140W similarity to human BTHS gene involved in Barth syndrome
0.045954 YPR139C "weak similarity to nGAP,H. sapiens nGAP mRNA"
*0.0995629 YGL121C hypothetical protein
*0.127329 YDR056C hypothetical protein
*0.204992 YMR135W-A questionable ORF
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4. RTS2
Inf-TRM
Module: 4
Regs: RTS2 #Support: 7 Similar_ratio: 0.67
------------------------
0.0397978 YGL005C weak similarity to Xenopus kinesin-related protein Eg5
0.0510597 YLR363C NAM7P interacting protein
0.0525886 YLR364W weak similarity to GRX2 Homo sapiens glutaredoxin 2
0.0538392 YJL162C weak similarity to dnaJ proteins
*0.101557 YBR210W strong similarity to D.melanogaster cornichon protein
*0.432242 YML045W YML045W
*- YML045W-A itG(GCC)M
Sup-TRM
Module: 7
Regs: RTS2 #Support: 8 Similar_ratio: 0.57
------------------------
0.0397978 YGL005C weak similarity to Xenopus kinesin-related protein Eg5
0.0510597 YLR363C NAM7P interacting protein
0.0525886 YLR364W weak similarity to GRX2 Homo sapiens glutaredoxin 2
0.0538392 YJL162C weak similarity to dnaJ proteins
*0.101557 YBR210W strong similarity to D.melanogaster cornichon protein
*0.103688 YPR072W component of the NOT protein complex
*0.432242 YML045W YML045W
*- YML045W-A itG(GCC)M
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5. MIG1
Inf-TRM
Module: 7
Regs: MIG1 #Support: 10 Similar_ratio: 0.5
------------------------
0.0392948 YLR417W defective in vacuolar protein sorting
0.0481231 YGL003C substrate-specific activator of APC-dependent proteolysis
0.0523266 YAL011W weak similarity to Mus musculus p53-associated cellular protein
0.0533757 YPR058W mitochondrial carrier protein (MCF)
0.0564294 YGL002W strong similarity to human gp25L2 protein
*0.0958474 YMR066W hypothetical protein
*0.134194 YLR415C questionable ORF
*0.139254 YLR416C hypothetical protein
*0.144763 YNR047W similarity to ser/thr protein kinases
*0.224073 YBR121C glycine--tRNA ligase
Sup-TRM
Module: 8
Regs: MIG1 #Support: 10 Similar_ratio: 0.5
------------------------
0.0392948 YLR417W defective in vacuolar protein sorting
0.0481231 YGL003C substrate-specific activator of APC-dependent proteolysis
0.0523266 YAL011W weak similarity to Mus musculus p53-associated cellular protein
0.0533757 YPR058W mitochondrial carrier protein (MCF)
0.0564294 YGL002W strong similarity to human gp25L2 protein
*0.0958474 YMR066W hypothetical protein
*0.134194 YLR415C questionable ORF
*0.139254 YLR416C hypothetical protein
*0.144763 YNR047W similarity to ser/thr protein kinases
*0.224073 YBR121C glycine--tRNA ligase
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6. RTG1
inf-TRM
Module: 8
Regs: RTG1 #Support: 4 Similar_ratio: 0.75
------------------------
0.0392291 YMR126C hypothetical protein
0.0441193 YKR098C ubiquitin C-terminal hydrolase
0.0504758 YKR099W transcription factor
*0.102196 YMR125W large subunit of the nuclear cap-binding protein complex CBC
Sup-TRM
Module: 9
Regs: RTG1 #Support: 11 Similar_ratio: 0.55
------------------------
0 YCR018C-A questionable ORF - identified by SAGE
0.0446442 YJL038C strong similarity to hypothetical protein YJL037w
0.0490545 YKR098C ubiquitin C-terminal hydrolase
0.0514004 YJL037W strong similarity to hypothetical protein YJL038c
0.0517374 YBL097W functional homologue of human BRRN1
0.0579987 YCR019W necessary for structural stability of L-A dsRNA-containing particles
*0.0800493 YMR126C hypothetical protein
*0.0886001 YKR099W transcription factor
*0.0975138 YJR100C weak similarity to BUD3P
*0.0964345 YKL071W weak similarity to A.parasiticus nor-1 protein
*0.129401 YMR125W large subunit of the nuclear cap-binding protein complex CBC
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7. HAP2_HAP3_HAP5
Inf-TRM
Module: 9
Regs: HAP5_HAP3_HAP2 #Support: 4 Similar_ratio: 1.0
------------------------
0.048107 YPL207W "similarity to hypthetical proteins from A. fulgidus, M. thermoautotrophicum and M. jannaschii"
0.0500839 YLR220W involved in calcium regulation
0.0533478 YLL027W mitochondrial protein required for normal iron metabolism
0.0587848 YER174C "member of the subfamily of yeast glutaredoxins (Grx3, GRX4, and Grx5)"
Sup-TRM
Module: 10
Regs: HAP5_HAP3_HAP2 #Support: 5 Similar_ratio: 0.8
------------------------
0.048107 YPL207W "similarity to hypthetical proteins from A. fulgidus, M. thermoautotrophicum and M. jannaschii"
0.0500839 YLR220W involved in calcium regulation
0.0533478 YLL027W mitochondrial protein required for normal iron metabolism
0.0587848 YER174C "member of the subfamily of yeast glutaredoxins (Grx3, GRX4, and Grx5)"
*0.10516 YHR051W cytochrome-c oxidase subunit VI
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8. GCR1
Inf-TRM
Module: 16
Regs: GCR1 #Support: 9 Similar_ratio: 0.67
------------------------
0 YBL107W-A questionable ORF - identified by SAGE
0 YER138W-A questionable ORF - identified by SAGE
0.041117 YGR215W strong similarity to hypothetical S. pombe protein
0.0417129 YKR027W strong similarity to CHS6P
*0.115472 YNL203C weak similarity to B.subtilis CDP-diacylglycerol--serine O-phosphatidyltransferase
*0.365298 YAL038W pyruvate kinase
*- YER137C-A iYERCdelta20
*- YPR158W-A iYPR158W
*- YPR158W-B iYPR158W
Sup-TRM
Module: 29
Regs: GCR1 #Support: 19 Similar_ratio: 0.5
------------------------
0 YBL107W-A questionable ORF - identified by SAGE
0 YER138W-A questionable ORF - identified by SAGE
0.0411682 YGR215W strong similarity to hypothetical S. pombe protein
0.0476221 YDR472W TRAPP subunit of 31 kDa involved in targeting and fusion of ER to golgi transport vesicles
0.0496078 YKR027W strong similarity to CHS6P
0.0586502 YDR240C "U1 snRNA protein, no counterpart in mammalian snRNP"
*0.111803 YNL203C weak similarity to B.subtilis CDP-diacylglycerol--serine O-phosphatidyltransferase
*0.170684 YJL148W nonessential component of RNA-polI
*0.30923 YBR196C glucose-6-phosphate isomerase
*0.341136 YER177W 14-3-3 protein involved in rapamycin-sensitive signalling
*0.37265 YAL038W pyruvate kinase
*0.440463 YGR192C glyceraldehyde-3-phosphate dehydrogenase 3
*- YDR210W-C YDRCTy1-2D
*- YER137C-A iYERCdelta20
*- YDR316W-A YDRWdelta23
*- YDR316W-B YDRWdelta23
*- YGR038C-A YGRCTy1-2D
*- YPR158W-A iYPR158W
*- YPR158W-B iYPR158W
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9. YJL206C_MCM1
Inf-TRM
Module: 21
Regs: YJL206C_MCM1 #Support: 6 Similar_ratio: 0.83
------------------------
0.0465809 YPL276W identical to a region of YOR388c
0.047562 YPL277C strong similarity to hypothetical protein YOR389w/putative pseudogene
0.0569001 YPL278C strong similarity to hypothetical protein YOR389w/putative pseudogene
0.0581733 YOR389W strong similarity to putative pseudogenes YPL277c and YPL278c
0.0605291 YPL275W identical to a region of YOR388c
*0.136543 YOR388C strong similarity to H.polymorpha formate dehydrogenase
Sup-TRM
Module: 43
Regs: YJL206C_MCM1 #Support: 9 Similar_ratio: 0.67
------------------------
0.045164 YPL276W identical to a region of YOR388c
0.0475597 YPL277C strong similarity to hypothetical protein YOR389w/putative pseudogene
0.053297 YEL045C weak similarity to cytochrome c oxidase III of T.brucei kinetoplast
0.0591199 YPL278C strong similarity to hypothetical protein YOR389w/putative pseudogene
0.0601912 YOR389W strong similarity to putative pseudogenes YPL277c and YPL278c
0.0631897 YPL275W identical to a region of YOR388c
*0.134526 YOR388C strong similarity to H.polymorpha formate dehydrogenase
*0.149019 YEL044W similarity to SPAC222.04c hypothetical protein S. pombe
*0.325103 YEL046C "L-threonine aldolase, low-specific"
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10. FKH1_FKH2_NDD1
Inf-TRM
Module: 30
Regs: FKH1_NDD1_FKH2 #Support: 5 Similar_ratio: 0.6
------------------------
0.0372971 YDR325W Yeast Condensin G
0.043815 YGR092W ser/thr protein kinase related to DBF20P
0.058179 YDR324C weak similarity to beta transducin from S. pombe and other WD-40 repeat containing proteins
*0.117175 YBR138C High-Dosage Reductional segregation defective
*0.134822 YBR139W strong similarity to carboxypeptidase
Sup-TRM
Module: 90
Regs: FKH1_NDD1_FKH2 #Support: 8 Similar_ratio: 0.5
------------------------
0.0450849 YDR325W Yeast Condensin G
0.0516369 YJR092W budding protein
0.0544713 YGR092W ser/thr protein kinase related to DBF20P
0.0557277 YDR324C weak similarity to beta transducin from S. pombe and other WD-40 repeat containing proteins
*0.092692 YJR091C suppresses the high-temperature lethality of TUB2-150
*0.110391 YIL158W similarity to hypothetical protein YKR100c
*0.136939 YBR139W strong similarity to carboxypeptidase
*0.109511 YBR138C High-Dosage Reductional segregation defective
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11. SUM1_GCN4
Inf-TRM
Module: 31
Regs: SUM1_GCN4 #Support: 5 Similar_ratio: 0.6
------------------------
0.0156773 YJR026W YJR026W
0.0209692 YJR028W YJR028W
0.034159 YJR029W YJR029W
*0.116242 YJR027W YJR027W
*0.295477 YJR025C 3-hydroxyanthranilic acid dioxygenase
Sup-TRM
Module: 91
Regs: SUM1_GCN4 #Support: 5 Similar_ratio: 0.6
------------------------
0.0156773 YJR026W YJR026W
0.0209692 YJR028W YJR028W
0.034159 YJR029W YJR029W
*0.116242 YJR027W YJR027W
*0.295477 YJR025C 3-hydroxyanthranilic acid dioxygenase
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12. GAT3_SWI5_YAP5
Inf-TRM
Module: 32
Regs: GAT3_SWI5_YAP5 #Support: 3 Similar_ratio: 1.0
------------------------
0.035545 YFL064C strong similarity to subtelomeric encoded proteins
0.0365705 YFL065C strong similarity to subtelomeric encoded proteins
0.0615544 YFL063W strong similarity to subtelomeric encoded proteins
Sup-TRM
Module: 95
Regs: GAT3_SWI5_YAP5 #Support: 8 Similar_ratio: 0.5
------------------------
0.0395841 YDR543C strong similarity to subtelomeric encoded proteins
0.0477718 YNL337W strong similarity to subtelomeric encoded proteins
0.0519471 YFL065C strong similarity to subtelomeric encoded proteins
0.0580144 YFL063W strong similarity to subtelomeric encoded proteins
*0.0976416 YFL064C strong similarity to subtelomeric encoded proteins
*0.107476 YHR091C "arginyl-tRNA synthetase, mitochondrial"
*0.183202 YGR296W strong similarity to YPL283c; YNL339c and other Y' encoded proteins
*0.191477 YPL283C strong similarity to subtelomeric encoded proteins
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13. PDR1_FHL1_RAP1
Inf-TRM
Module: 34
Regs: PDR1_FHL1_RAP1 #Support: 4 Similar_ratio: 0.75
------------------------
0.0476856 YDR471W 60S large subunit ribosomal protein
0.0550738 YER074W 40s small subunit ribosomal protein S24.e
0.0551023 YEL054C 60S large subunit ribosomal protein L12.e
*0.252031 YDR470C similarity to chromosome segregation protein CSE1P
Sup-TRM
Module: 98
Regs: PDR1_FHL1_RAP1 #Support: 10 Similar_ratio: 0.6
------------------------
0 YPL249C-A 60S large subunit ribosomal protein
0.0428398 YER074W 40s small subunit ribosomal protein S24.e
0.0505724 YHR141C ribosomal protein L36a.e
0.0513858 YIL133C 60S large subunit ribosomal protein
0.0627899 YDR471W 60S large subunit ribosomal protein
0.064111 YNL069C 60S large subunit ribosomal protein
*0.0796244 YEL054C 60S large subunit ribosomal protein L12.e
*0.0880907 YBL087C 60S large subunit ribosomal protein L23.e
*0.15023 YHR142W control of protein export from the ER (like chitin synthase III)
*0.254309 YDR470C similarity to chromosome segregation protein CSE1P
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