SFP1 FHL1 5 (4) YBR048W=D <= FHL1=D SFP1=D b YBR048W RPS11B 982 protein biosynthesis* structural constituent of ribosome cytosolic small ribosomal subunit (sensu Eukaryota) S000000252 YBR085W=D <= FHL1=D SFP1=D b YBR085W AAC3 924 anaerobic respiration ATP:ADP antiporter activity mitochondrial inner membrane S000000289 YHR021W-A=D <= FHL1=I SFP1=I b YHR021W-A ECM12 456 cell wall organization and biogenesis molecular_function unknown cellular_component unknown S000003531 YIL133C=D <= FHL1=D SFP1=D b YIL133C RPL16A 890 protein biosynthesis structural constituent of ribosome* cytosolic large ribosomal subunit (sensu Eukaryota) S000001395 STB1 MBP1 7 (7) YCR065W=D <= MBP1=D STB1=D b YCR065W HCM1 1695 transcription initiation from Pol II promoter* specific RNA polymerase II transcription factor activity nucleus S000000661 YGR109C=D <= MBP1=D STB1=D abc YGR109C CLB6 1143 G1/S transition of mitotic cell cycle* cyclin-dependent protein kinase regulator activity cellular_component unknown S000003341 YHR061C=D <= MBP1=D STB1=D b YHR061C GIC1 945 establishment of cell polarity (sensu Fungi)* small GTPase regulatory/interacting protein activity bud neck* S000001103 YMR307W=D <= MBP1=D STB1=D ab YMR307W GAS1 1680 cell wall organization and biogenesis "1,3-beta-glucanosyltransferase activity" mitochondrion* S000004924 YOL007C=D <= MBP1=D STB1=D b YOL007C 1026 biological_process unknown molecular_function unknown vacuole (sensu Fungi)* S000005367 YOR246C=D <= MBP1=D STB1=D b YOR246C 993 biological_process unknown oxidoreductase activity lipid particle S000005772 YOR247W=D <= MBP1=D STB1=D b YOR247W SRL1 633 "nucleobase, nucleoside, nucleotide and nucleic acid metabolism" molecular_function unknown cytoplasm* S000005773 MET4 MET32 7 (6) YAL012W=D <= MET32=I MET4=I a YAL012W CYS3 1185 sulfur amino acid metabolism* cystathionine gamma-lyase activity cytoplasm S000000010 YGL184C=D <= MET32=D MET4=D ab YGL184C STR3 1398 methionine biosynthesis cystathionine beta-lyase activity peroxisome S000003152 YGR055W=D <= MET32=D MET4=D b YGR055W MUP1 1725 sulfur amino acid transport L-methionine porter activity integral to plasma membrane S000003287 YGR055W=D <= MET32=I MET4=I a YGR055W MUP1 1725 sulfur amino acid transport L-methionine porter activity integral to plasma membrane S000003287 YLR179C=D <= MET32=I MET4=I ab YLR179C 606 biological_process unknown molecular_function unknown cytoplasm* S000004169 YLR180W=D <= MET32=I MET4=I a YLR180W SAM1 1149 methionine metabolism methionine adenosyltransferase activity cytoplasm S000004170 HAP3 HAP4 4 (4) YBR039W=D <= HAP3=D HAP4=D a YBR039W ATP3 936 ATP synthesis coupled proton transport "hydrogen-transporting ATP synthase activity, rotational mechanism" "proton-transporting ATP synthase, central stalk (sensu Eukaryota)" S000000243 YDR377W=D <= HAP3=D HAP4=D a YDR377W ATP17 306 ATP synthesis coupled proton transport "hydrogen-transporting ATP synthase activity, rotational mechanism" "proton-transporting ATP synthase complex, coupling factor F(o) (sensu Eukaryota)" S000002785 YDR377W=D <= HAP3=I HAP4=D b YDR377W ATP17 306 ATP synthesis coupled proton transport "hydrogen-transporting ATP synthase activity, rotational mechanism" "proton-transporting ATP synthase complex, coupling factor F(o) (sensu Eukaryota)" S000002785 YML120C=D <= HAP3=D HAP4=D a YML120C NDI1 1542 "mitochondrial electron transport, NADH to ubiquinone" "oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor" mitochondrial inner membrane S000004589 DAL80 SOK2 4 (1) YOR030W=D <= DAL80=D SOK2=D ab YOR030W DFG16 1860 invasive growth (sensu Saccharomyces) molecular_function unknown cellular_component unknown S000005556 BAS1 REB1 4 (4) YMR188C=D <= BAS1=I REB1=I ab YMR188C MRPS17 714 protein biosynthesis* structural constituent of ribosome mitochondrial small ribosomal subunit S000004800 YMR189W=D <= BAS1=I REB1=I b YMR189W GCV2 3105 one-carbon compound metabolism glycine dehydrogenase (decarboxylating) activity mitochondrion S000004801 YNL220W=D <= BAS1=I REB1=I b YNL220W ADE12 1302 purine nucleotide biosynthesis* adenylosuccinate synthase activity cytoplasm S000005164 YNL221C=D <= BAS1=D REB1=D a YNL221C POP1 2628 rRNA processing* ribonuclease P activity* ribonuclease MRP complex* S000005165 BAS1 GCN4 5 (4) YGR204W=D <= BAS1=D GCN4=I a YGR204W ADE3 2841 purine base biosynthesis* formate-tetrahydrofolate ligase activity* cytoplasm* S000003436 YLR058C=D <= BAS1=D GCN4=I a YLR058C SHM2 1410 one-carbon compound metabolism glycine hydroxymethyltransferase activity cytoplasm S000004048 YLR058C=D <= BAS1=I GCN4=I b YLR058C SHM2 1410 one-carbon compound metabolism glycine hydroxymethyltransferase activity cytoplasm S000004048 YMR189W=D <= BAS1=I GCN4=I ab YMR189W GCV2 3105 one-carbon compound metabolism glycine dehydrogenase (decarboxylating) activity mitochondrion S000004801 ACE2 SWI4 5 (4) YBR162C=D <= ACE2=D SWI4=D bc YBR162C TOS1 1368 biological_process unknown molecular_function unknown cell wall (sensu Fungi)* S000000366 YDL055C=D <= ACE2=D SWI4=D c YDL055C PSA1 1086 protein amino acid glycosylation* mannose-1-phosphate guanylyltransferase activity cytoplasm S000002213 YDL127W=D <= ACE2=I SWI4=I c YDL127W PCL2 927 cell cycle cyclin-dependent protein kinase regulator activity cyclin-dependent protein kinase holoenzyme complex S000002285 YGR041W=D <= ACE2=D SWI4=D bc YGR041W BUD9 1644 bud site selection molecular_function unknown bud neck S000003273 MET32 CBF1 5 (4) YER091C=D <= CBF1=D MET32=D a YER091C MET6 2304 methionine biosynthesis 5-methyltetrahydropteroyltriglutamate-homocysteine S-methyltransferase activity cytoplasm S000000893 YJR010W=D <= CBF1=D MET32=D ab YJR010W MET3 1536 methionine metabolism* sulfate adenylyltransferase (ATP) activity cytoplasm* S000003771 YLR092W=D <= CBF1=D MET32=D ab YLR092W SUL2 2682 sulfate transport sulfate transporter activity plasma membrane S000004082 YNL277W=D <= CBF1=D MET32=D ab YNL277W MET2 1461 methionine biosynthesis* homoserine O-acetyltransferase activity cytoplasm S000005221 TYE7 ABF1 4 (3) YDL051W=D <= ABF1=D TYE7=D ab YDL051W LHP1 828 tRNA processing RNA binding nucleus* S000002209 YDL074C=D <= ABF1=D TYE7=D b YDL074C BRE1 2103 chromatin silencing at telomere* ubiquitin-protein ligase activity nucleus S000002232 YKL016C=D <= ABF1=I TYE7=I b YKL016C ATP7 525 protein complex assembly* structural molecule activity* "proton-transporting ATP synthase, stator stalk (sensu Eukaryota)" S000001499 TYE7 CBF1 15 (13) YAL026C=D <= CBF1=I TYE7=I a YAL026C DRS2 4068 processing of 20S pre-rRNA* ATPase activity* plasma membrane* S000000024 YBR039W=D <= CBF1=I TYE7=I ab YBR039W ATP3 936 ATP synthesis coupled proton transport "hydrogen-transporting ATP synthase activity, rotational mechanism" "proton-transporting ATP synthase, central stalk (sensu Eukaryota)" S000000243 YCR088W=D <= CBF1=D TYE7=D ab YCR088W ABP1 1779 establishment of cell polarity (sensu Fungi)* protein binding cytoplasm* S000000684 YEL046C=D <= CBF1=D TYE7=D a YEL046C GLY1 1164 threonine catabolism* threonine aldolase activity cytosol S000000772 YFR030W=D <= CBF1=D TYE7=D bc YFR030W MET10 3108 sulfate assimilation sulfite reductase (NADPH) activity sulfite reductase complex (NADPH) S000001926 YGR224W=D <= CBF1=I TYE7=D c YGR224W AZR1 1842 azole transport azole transporter activity plasma membrane S000003456 YJR009C=D <= CBF1=D TYE7=D a YJR009C TDH2 999 gluconeogenesis* glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) activity cytoplasm* S000003769 YJR137C=D <= CBF1=D TYE7=D b YJR137C ECM17 4329 cell wall organization and biogenesis* sulfite reductase (NADPH) activity cytoplasm* S000003898 YJR138W=D <= CBF1=I TYE7=I b YJR138W IML1 4755 biological_process unknown molecular_function unknown vacuolar membrane (sensu Fungi) S000003899 YKL192C=D <= CBF1=D TYE7=D a YKL192C ACP1 378 fatty acid biosynthesis acyl carrier activity mitochondrion S000001675 YMR196W=D <= CBF1=D TYE7=I a YMR196W 3267 biological_process unknown molecular_function unknown cytoplasm S000004809 YMR308C=D <= CBF1=D TYE7=D a YMR308C PSE1 3270 mRNA-nucleus export protein carrier activity cytoplasm* S000004925 YNR051C=D <= CBF1=D TYE7=D b YNR051C BRE5 1548 protein deubiquitination molecular_function unknown cytoplasm S000005334 PHO4 CBF1 6 (4) YCL034W=D <= CBF1=D PHO4=D b YCL034W LSB5 1065 actin filament organization* molecular_function unknown cell cortex S000000539 YJL117W=D <= CBF1=D PHO4=D b YJL117W PHO86 936 secretory pathway* molecular_function unknown endoplasmic reticulum S000003653 YJR145C=D <= CBF1=D PHO4=D b YJR145C RPS4A 1042 protein biosynthesis* structural constituent of ribosome cytoplasm* S000003906 YML123C=D <= CBF1=D PHO4=D a YML123C PHO84 1764 phosphate transport* inorganic phosphate transporter activity* integral to plasma membrane S000004592 PHO4 NRG1 6 (6) YBR296C=D <= NRG1=I PHO4=I bc YBR296C PHO89 1725 phosphate transport sodium:inorganic phosphate symporter activity plasma membrane S000000500 YBR297W=D <= NRG1=D PHO4=D a YBR297W MAL33 1407 "regulation of transcription, DNA-dependent*" transcription factor activity nucleus S000000501 YBR297W=D <= NRG1=I PHO4=I b YBR297W MAL33 1407 "regulation of transcription, DNA-dependent*" transcription factor activity nucleus S000000501 YDL049C=D <= NRG1=D PHO4=D a YDL049C KNH1 807 "beta-1,6 glucan biosynthesis" molecular_function unknown cell wall (sensu Fungi)* S000002207 YPL018W=D <= NRG1=D PHO4=I b YPL018W CTF19 1110 chromosome segregation* protein binding nucleus* S000005939 YPL019C=D <= NRG1=I PHO4=I a YPL019C VTC3 2508 "vacuole fusion, non-autophagic" molecular_function unknown vacuolar membrane S000005940 PHO4 RAP1 6 (5) YJR145C=D <= PHO4=D RAP1=D ab YJR145C RPS4A 1042 protein biosynthesis* structural constituent of ribosome cytoplasm* S000003906 YJR147W=D <= PHO4=D RAP1=D ab YJR147W HMS2 1077 pseudohyphal growth molecular_function unknown cytoplasm* S000003908 YJR147W=D <= PHO4=D RAP1=I b YJR147W HMS2 1077 pseudohyphal growth molecular_function unknown cytoplasm* S000003908 YKL150W=D <= PHO4=I RAP1=I ab YKL150W MCR1 909 response to oxidative stress* cytochrome-b5 reductase activity mitochondrial intermembrane space* S000001633 YKL151C=D <= PHO4=I RAP1=I ab YKL151C 1014 biological_process unknown molecular_function unknown cytoplasm S000001634 ASH1 HSF1 4 (2) YBR067C=D <= ASH1=D HSF1=I a YBR067C TIP1 633 cell wall organization and biogenesis structural constituent of cell wall* cell wall (sensu Fungi) S000000271 YFL016C=D <= ASH1=D HSF1=D bc YFL016C MDJ1 1536 protein folding* unfolded protein binding* mitochondrial inner membrane S000001878 ASH1 PHD1 6 (3) YBR067C=D <= ASH1=D PHD1=I a YBR067C TIP1 633 cell wall organization and biogenesis structural constituent of cell wall* cell wall (sensu Fungi) S000000271 YPL058C=D <= ASH1=D PHD1=D c YPL058C PDR12 4536 transport* xenobiotic-transporting ATPase activity* plasma membrane S000005979 YPR013C=D <= ASH1=D PHD1=D ab YPR013C 954 biological_process unknown molecular_function unknown cellular_component unknown S000006217 ASH1 NRG1 7 (3) YPL024W=D <= ASH1=I NRG1=D a YPL024W NCE4 726 biological_process unknown molecular_function unknown cytoplasm* S000005945 YPL026C=D <= ASH1=I NRG1=D a YPL026C SKS1 1509 protein amino acid phosphorylation* protein serine/threonine kinase activity cytoplasm S000005947 YPR013C=D <= ASH1=D NRG1=D a YPR013C 954 biological_process unknown molecular_function unknown cellular_component unknown S000006217 HAP2 HAP4 11 (11) YBL099W=D <= HAP2=D HAP4=D a YBL099W ATP1 1638 ATP synthesis coupled proton transport "hydrogen-transporting ATP synthase activity, rotational mechanism" "proton-transporting ATP synthase, catalytic core (sensu Eukaryota)" S000000195 YBR039W=D <= HAP2=D HAP4=D a YBR039W ATP3 936 ATP synthesis coupled proton transport "hydrogen-transporting ATP synthase activity, rotational mechanism" "proton-transporting ATP synthase, central stalk (sensu Eukaryota)" S000000243 YDL067C=D <= HAP2=D HAP4=D a YDL067C COX9 180 aerobic respiration cytochrome-c oxidase activity respiratory chain complex IV (sensu Eukaryota) S000002225 YDL181W=D <= HAP2=I HAP4=I b YDL181W INH1 258 ATP synthesis coupled proton transport enzyme inhibitor activity proton-transporting ATP synthase complex (sensu Eukaryota) S000002340 YDR377W=D <= HAP2=D HAP4=D a YDR377W ATP17 306 ATP synthesis coupled proton transport "hydrogen-transporting ATP synthase activity, rotational mechanism" "proton-transporting ATP synthase complex, coupling factor F(o) (sensu Eukaryota)" S000002785 YDR529C=D <= HAP2=D HAP4=D a YDR529C QCR7 384 aerobic respiration* ubiquinol-cytochrome-c reductase activity respiratory chain complex III (sensu Eukaryota) S000002937 YEL024W=D <= HAP2=D HAP4=D a YEL024W RIP1 648 aerobic respiration* ubiquinol-cytochrome-c reductase activity respiratory chain complex III (sensu Eukaryota) S000000750 YFR033C=D <= HAP2=D HAP4=D a YFR033C QCR6 444 aerobic respiration* ubiquinol-cytochrome-c reductase activity mitochondrion* S000001929 YFR033C=D <= HAP2=I HAP4=I b YFR033C QCR6 444 aerobic respiration* ubiquinol-cytochrome-c reductase activity mitochondrion* S000001929 YHR051W=D <= HAP2=D HAP4=D a YHR051W COX6 447 aerobic respiration cytochrome-c oxidase activity respiratory chain complex IV (sensu Eukaryota) S000001093 YMR256C=D <= HAP2=I HAP4=I b YMR256C COX7 183 aerobic respiration cytochrome-c oxidase activity respiratory chain complex IV (sensu Eukaryota) S000004869 GAT1 DAL82 5 (2) YGR180C=D <= DAL82=D GAT1=D a YGR180C RNR4 1038 DNA replication ribonucleoside-diphosphate reductase activity cytoplasm* S000003412 YIR027C=D <= DAL82=I GAT1=D a YIR027C DAL1 1383 allantoin catabolism allantoinase activity intracellular S000001466 GAT1 GLN3 7 (4) YIR005W=D <= GAT1=I GLN3=I b YIR005W IST3 447 spliceosome assembly pre-mRNA splicing factor activity snRNP U2 S000001444 YIR029W=D <= GAT1=D GLN3=D a YIR029W DAL2 1032 allantoin catabolism allantoicase activity cellular_component unknown S000001468 YIR031C=D <= GAT1=D GLN3=D a YIR031C DAL7 1665 allantoin catabolism malate synthase activity cytoplasm S000001470 YJR152W=D <= GAT1=D GLN3=D a YJR152W DAL5 1632 allantoate transport allantoate transporter activity plasma membrane S000003913 MSN2 CIN5 4 (3) YBR072W=D <= CIN5=D MSN2=D ab YBR072W HSP26 645 response to stress* unfolded protein binding cytoplasm* S000000276 YDR033W=D <= CIN5=I MSN2=I a YDR033W MRH1 963 biological_process unknown molecular_function unknown mitochondrion* S000002440 YOL052C-A=D <= CIN5=D MSN2=D b YOL052C-A DDR2 186 response to stress molecular_function unknown cytoplasm* S000005413 MSN2 HSF1 4 (4) YBR072W=D <= HSF1=D MSN2=D ab YBR072W HSP26 645 response to stress* unfolded protein binding cytoplasm* S000000276 YDR171W=D <= HSF1=D MSN2=D ab YDR171W HSP42 1128 response to stress* unfolded protein binding cytoplasm* S000002578 YER103W=D <= HSF1=D MSN2=D abc YER103W SSA4 1929 response to stress* unfolded protein binding cytoplasm* S000000905 YJR045C=D <= HSF1=D MSN2=D ab YJR045C SSC1 1965 protein folding* ATPase activity* mitochondrion* S000003806 MSN2 MSN4 15 (13) YAL060W=D <= MSN2=D MSN4=D ab YAL060W BDH1 1149 butanediol fermentation "(R,R)-butanediol dehydrogenase activity" cytoplasm S000000056 YDR032C=D <= MSN2=I MSN4=D ab YDR032C PST2 597 biological_process unknown molecular_function unknown cytoplasm* S000002439 YGR008C=D <= MSN2=D MSN4=D ab YGR008C STF2 255 ATP synthesis coupled proton transport* molecular_function unknown proton-transporting ATP synthase complex (sensu Eukaryota) S000003240 YGR008C=D <= MSN2=I MSN4=D ab YGR008C STF2 255 ATP synthesis coupled proton transport* molecular_function unknown proton-transporting ATP synthase complex (sensu Eukaryota) S000003240 YGR088W=D <= MSN2=D MSN4=D ab YGR088W CTT1 1722 response to stress catalase activity cytoplasm S000003320 YJL164C=D <= MSN2=D MSN4=D abc YJL164C TPK1 1194 protein amino acid phosphorylation* protein serine/threonine kinase activity* cytoplasm* S000003700 YKL085W=D <= MSN2=I MSN4=D ab YKL085W MDH1 1005 tricarboxylic acid cycle* L-malate dehydrogenase activity mitochondrial matrix S000001568 YKL101W=D <= MSN2=D MSN4=D bc YKL101W HSL1 4557 protein amino acid phosphorylation* protein kinase activity bud neck* S000001584 YKR066C=D <= MSN2=D MSN4=D b YKR066C CCP1 1086 response to oxidative stress cytochrome-c peroxidase activity mitochondrion* S000001774 YKR067W=D <= MSN2=D MSN4=D b YKR067W GPT2 2232 phospholipid biosynthesis glycerol-3-phosphate O-acyltransferase activity cytoplasm* S000001775 YLL026W=D <= MSN2=I MSN4=I c YLL026W HSP104 2727 response to stress* chaperone binding* cytoplasm* S000003949 YMR173W=D <= MSN2=I MSN4=D ab YMR173W DDR48 1293 DNA repair ATPase activity* cytoplasm S000004784 YOL113W=D <= MSN2=D MSN4=D c YOL113W SKM1 1968 protein amino acid phosphorylation* protein serine/threonine kinase activity cellular_component unknown S000005473 ROX1 SOK2 5 (5) YDL048C=D <= ROX1=D SOK2=D ac YDL048C STP4 1473 biological_process unknown molecular_function unknown cytoplasm* S000002206 YDR077W=D <= ROX1=D SOK2=I a YDR077W SED1 1017 cell wall organization and biogenesis structural constituent of cell wall cell wall (sensu Fungi)* S000002484 YER010C=D <= ROX1=D SOK2=I b YER010C 705 biological_process unknown molecular_function unknown cellular_component unknown S000000812 YGL006W=D <= ROX1=D SOK2=D c YGL006W PMC1 3522 calcium ion homeostasis* calcium-transporting ATPase activity vacuolar membrane (sensu Fungi) S000002974 YPL230W=D <= ROX1=D SOK2=I a YPL230W 1176 biological_process unknown molecular_function unknown cellular_component unknown S000006151 ROX1 PHD1 6 (6) YDL048C=D <= PHD1=D ROX1=D ac YDL048C STP4 1473 biological_process unknown molecular_function unknown cytoplasm* S000002206 YDL048C=D <= PHD1=I ROX1=D a YDL048C STP4 1473 biological_process unknown molecular_function unknown cytoplasm* S000002206 YDL048C=D <= PHD1=I ROX1=I b YDL048C STP4 1473 biological_process unknown molecular_function unknown cytoplasm* S000002206 YDR011W=D <= PHD1=D ROX1=D bc YDR011W SNQ2 4506 response to drug* xenobiotic-transporting ATPase activity mitochondrion* S000002418 YMR195W=D <= PHD1=D ROX1=D ab YMR195W ICY1 384 biological_process unknown molecular_function unknown vacuolar membrane (sensu Fungi) S000004808 YPL265W=D <= PHD1=D ROX1=D abc YPL265W DIP5 1827 amino acid transport amino acid transporter activity* plasma membrane S000006186 YAP1 CAD1 8 (7) YDR533C=D <= CAD1=D YAP1=D ab YDR533C HSP31 714 biological_process unknown unfolded protein binding* soluble fraction S000002941 YJL101C=D <= CAD1=D YAP1=D ab YJL101C GSH1 2037 glutathione biosynthesis* glutamate-cysteine ligase activity intracellular S000003637 YKL087C=D <= CAD1=D YAP1=D ab YKL087C CYT2 675 cytochrome c-heme linkage holocytochrome-c synthase activity mitochondrial intermembrane space S000001570 YLL058W=D <= CAD1=D YAP1=D b YLL058W 1728 sulfur metabolism cystathionine gamma-synthase activity cellular_component unknown S000003981 YLL060C=D <= CAD1=D YAP1=D ab YLL060C GTT2 702 glutathione metabolism glutathione transferase activity mitochondrion S000003983 YMR038C=D <= CAD1=D YAP1=D b YMR038C CCS1 750 intracellular copper ion transport superoxide dismutase copper chaperone activity cytosol* S000004641 YOL119C=D <= CAD1=D YAP1=D ab YOL119C MCH4 1506 transport transporter activity* vacuolar membrane (sensu Fungi) S000005479 YAP1 YAP7 14 (12) YDR533C=D <= YAP1=D YAP7=I ab YDR533C HSP31 714 biological_process unknown unfolded protein binding* soluble fraction S000002941 YFL056C=D <= YAP1=D YAP7=I ab YFL056C AAD6 639 aldehyde metabolism aryl-alcohol dehydrogenase activity cellular_component unknown S000001838 YGR209C=D <= YAP1=D YAP7=D b YGR209C TRX2 315 response to oxidative stress* thiol-disulfide exchange intermediate activity cytosol* S000003441 YJR104C=D <= YAP1=D YAP7=I b YJR104C SOD1 465 zinc ion homeostasis* "copper, zinc superoxide dismutase activity" cytosol* S000003865 YJR105W=D <= YAP1=I YAP7=D ab YJR105W ADO1 1023 purine base metabolism adenosine kinase activity cytoplasm* S000003866 YKR052C=D <= YAP1=D YAP7=D ab YKR052C MRS4 915 transport* iron ion transporter activity* mitochondrion S000001760 YLL060C=D <= YAP1=D YAP7=D ab YLL060C GTT2 702 glutathione metabolism glutathione transferase activity mitochondrion S000003983 YLL060C=D <= YAP1=D YAP7=I ab YLL060C GTT2 702 glutathione metabolism glutathione transferase activity mitochondrion S000003983 YLR075W=D <= YAP1=I YAP7=D a YLR075W RPL10 666 protein biosynthesis* structural constituent of ribosome cytosolic large ribosomal subunit (sensu Eukaryota) S000004065 YMR038C=D <= YAP1=D YAP7=D ab YMR038C CCS1 750 intracellular copper ion transport superoxide dismutase copper chaperone activity cytosol* S000004641 YMR318C=D <= YAP1=I YAP7=D a YMR318C ADH6 1083 aldehyde metabolism* alcohol dehydrogenase (NADP+) activity soluble fraction S000004937 YPL091W=D <= YAP1=D YAP7=D ab YPL091W GLR1 1452 response to oxidative stress glutathione-disulfide reductase activity cytoplasm* S000006012 CAD1 GCN4 6 (4) YEL044W=D <= CAD1=I GCN4=D ab YEL044W IES6 501 metabolism molecular_function unknown nucleus S000000770 YEL046C=D <= CAD1=I GCN4=D ab YEL046C GLY1 1164 threonine catabolism* threonine aldolase activity cytosol S000000772 YKL101W=D <= CAD1=I GCN4=I a YKL101W HSL1 4557 protein amino acid phosphorylation* protein kinase activity bud neck* S000001584 YKL103C=D <= CAD1=D GCN4=I ab YKL103C LAP4 1545 vacuolar protein catabolism aminopeptidase I activity vacuole (sensu Fungi) S000001586 CAD1 MSN4 8 (6) YHR008C=D <= CAD1=D MSN4=I a YHR008C SOD2 702 replicative cell aging* manganese superoxide dismutase activity mitochondrion* S000001050 YJL100W=D <= CAD1=D MSN4=D a YJL100W LSB6 1824 actin filament organization 1-phosphatidylinositol 4-kinase activity cytoplasm* S000003636 YJL101C=D <= CAD1=D MSN4=D b YJL101C GSH1 2037 glutathione biosynthesis* glutamate-cysteine ligase activity intracellular S000003637 YKL103C=D <= CAD1=D MSN4=D ab YKL103C LAP4 1545 vacuolar protein catabolism aminopeptidase I activity vacuole (sensu Fungi) S000001586 YKL103C=D <= CAD1=D MSN4=I a YKL103C LAP4 1545 vacuolar protein catabolism aminopeptidase I activity vacuole (sensu Fungi) S000001586 YOL119C=D <= CAD1=D MSN4=D abc YOL119C MCH4 1506 transport transporter activity* vacuolar membrane (sensu Fungi) S000005479 CAD1 YAP7 16 (16) YDR533C=D <= CAD1=D YAP7=D ab YDR533C HSP31 714 biological_process unknown unfolded protein binding* soluble fraction S000002941 YDR533C=D <= CAD1=D YAP7=I ab YDR533C HSP31 714 biological_process unknown unfolded protein binding* soluble fraction S000002941 YER141W=D <= CAD1=D YAP7=D ab YER141W COX15 1461 cytochrome c oxidase biogenesis* "oxidoreductase activity, acting on NADH or NADPH, heme protein as acceptor" mitochondrial inner membrane S000000943 YKL087C=D <= CAD1=D YAP7=I a YKL087C CYT2 675 cytochrome c-heme linkage holocytochrome-c synthase activity mitochondrial intermembrane space S000001570 YKL101W=D <= CAD1=D YAP7=D b YKL101W HSL1 4557 protein amino acid phosphorylation* protein kinase activity bud neck* S000001584 YKL103C=D <= CAD1=D YAP7=I ab YKL103C LAP4 1545 vacuolar protein catabolism aminopeptidase I activity vacuole (sensu Fungi) S000001586 YKR052C=D <= CAD1=D YAP7=I ab YKR052C MRS4 915 transport* iron ion transporter activity* mitochondrion S000001760 YKR071C=D <= CAD1=I YAP7=I b YKR071C DRE2 1047 biological_process unknown molecular_function unknown cytoplasm S000001779 YLL058W=D <= CAD1=D YAP7=D b YLL058W 1728 sulfur metabolism cystathionine gamma-synthase activity cellular_component unknown S000003981 YLL060C=D <= CAD1=D YAP7=D ab YLL060C GTT2 702 glutathione metabolism glutathione transferase activity mitochondrion S000003983 YML116W=D <= CAD1=D YAP7=I b YML116W ATR1 1629 multidrug transport multidrug efflux pump activity plasma membrane S000004584 YMR038C=D <= CAD1=I YAP7=D a YMR038C CCS1 750 intracellular copper ion transport superoxide dismutase copper chaperone activity cytosol* S000004641 YOR173W=D <= CAD1=D YAP7=D ab YOR173W DCS2 1194 biological_process unknown molecular_function unknown cytoplasm S000005699 YOR173W=D <= CAD1=D YAP7=I ab YOR173W DCS2 1194 biological_process unknown molecular_function unknown cytoplasm S000005699 YPL171C=D <= CAD1=D YAP7=D a YPL171C OYE3 1203 biological_process unknown NADPH dehydrogenase activity cellular_component unknown S000006092 YPR048W=D <= CAD1=I YAP7=I a YPR048W TAH18 1872 biological_process unknown molecular_function unknown cellular_component unknown S000006252 INO2 CBF1 6 (6) YER043C=D <= CBF1=D INO2=I a YER043C SAH1 1350 methionine metabolism* adenosylhomocysteinase activity cytoplasm S000000845 YER043C=D <= CBF1=I INO2=D b YER043C SAH1 1350 methionine metabolism* adenosylhomocysteinase activity cytoplasm S000000845 YJL149W=D <= CBF1=I INO2=I b YJL149W 1992 biological_process unknown molecular_function unknown SCF ubiquitin ligase complex S000003685 YJL151C=D <= CBF1=D INO2=I b YJL151C SNA3 402 biological_process unknown molecular_function unknown membrane* S000003687 YJL151C=D <= CBF1=I INO2=D a YJL151C SNA3 402 biological_process unknown molecular_function unknown membrane* S000003687 YJL151C=D <= CBF1=I INO2=I b YJL151C SNA3 402 biological_process unknown molecular_function unknown membrane* S000003687 INO2 INO4 14 (13) YBR029C=D <= INO2=I INO4=I a YBR029C CDS1 1374 phosphatidylglycerol biosynthesis* phosphatidate cytidylyltransferase activity mitochondrion* S000000233 YCR057C=D <= INO2=I INO4=I ab YCR057C PWP2 2772 processing of 20S pre-rRNA* snoRNA binding cytoplasm* S000000653 YDR146C=D <= INO2=I INO4=I a YDR146C SWI5 2130 G1-specific transcription in mitotic cell cycle transcriptional activator activity cytoplasm* S000002553 YDR497C=D <= INO2=D INO4=D b YDR497C ITR1 1755 myo-inositol transport myo-inositol transporter activity membrane S000002905 YDR497C=D <= INO2=I INO4=I a YDR497C ITR1 1755 myo-inositol transport myo-inositol transporter activity membrane S000002905 YER043C=D <= INO2=I INO4=I ab YER043C SAH1 1350 methionine metabolism* adenosylhomocysteinase activity cytoplasm S000000845 YER091C=D <= INO2=I INO4=I a YER091C MET6 2304 methionine biosynthesis 5-methyltetrahydropteroyltriglutamate-homocysteine S-methyltransferase activity cytoplasm S000000893 YJL153C=D <= INO2=D INO4=D a YJL153C INO1 1602 myo-inositol metabolism inositol-3-phosphate synthase activity cytoplasm S000003689 YJR105W=D <= INO2=D INO4=I b YJR105W ADO1 1023 purine base metabolism adenosine kinase activity cytoplasm* S000003866 YJR105W=D <= INO2=I INO4=I ab YJR105W ADO1 1023 purine base metabolism adenosine kinase activity cytoplasm* S000003866 YNL044W=D <= INO2=I INO4=I a YNL044W YIP3 610 ER to Golgi transport molecular_function unknown COPII-coated vesicle S000004989 YNL169C=D <= INO2=I INO4=I a YNL169C PSD1 1503 phosphatidylcholine biosynthesis phosphatidylserine decarboxylase activity mitochondrion* S000005113 YNR017W=D <= INO2=I INO4=I a YNR017W MAS6 669 mitochondrial matrix protein import protein transporter activity mitochondrion* S000005300 TEC1 DIG1 13 (7) YAR014C=D <= DIG1=D TEC1=D b YAR014C BUD14 2124 cellular morphogenesis during vegetative growth molecular_function unknown bud neck* S000000069 YAR015W=D <= DIG1=I TEC1=I b YAR015W ADE1 921 purine nucleotide biosynthesis* phosphoribosylaminoimidazolesuccinocarboxamide synthase activity cytoplasm* S000000070 YBR011C=D <= DIG1=D TEC1=D a YBR011C IPP1 864 phosphate metabolism inorganic diphosphatase activity cytosol S000000215 YGR189C=D <= DIG1=D TEC1=I ac YGR189C CRH1 1524 biological_process unknown molecular_function unknown cell wall (sensu Fungi)* S000003421 YKL096W=D <= DIG1=D TEC1=D ab YKL096W CWP1 720 cell wall organization and biogenesis structural constituent of cell wall cell wall (sensu Fungi) S000001579 YLR452C=D <= DIG1=D TEC1=I b YLR452C SST2 2097 signal transduction* GTPase activator activity plasma membrane S000004444 YNL053W=D <= DIG1=D TEC1=D b YNL053W MSG5 1470 protein amino acid dephosphorylation* prenylated protein tyrosine phosphatase activity cytoplasm S000004998 TEC1 DIG1 STE12 4 (4) YAR015W=D <= DIG1=I STE12=I TEC1=I b YAR015W ADE1 921 purine nucleotide biosynthesis* phosphoribosylaminoimidazolesuccinocarboxamide synthase activity cytoplasm* S000000070 YBR012W-A=D <= DIG1=D STE12=D TEC1=D b YKL095W=D <= DIG1=D STE12=D TEC1=D b YKL095W YJU2 837 "nuclear mRNA splicing, via spliceosome" molecular_function unknown nucleus S000001578 YMR065W=D <= DIG1=I STE12=I TEC1=I b YMR065W KAR5 1515 karyogamy during conjugation with cellular fusion molecular_function unknown mitochondrion* S000004669 TEC1 STE12 23 (16) YBR012W-B=D <= STE12=D TEC1=D a YCL054W=D <= STE12=D TEC1=I a YCL054W SPB1 2526 processing of 27S pre-rRNA S-adenosylmethionine-dependent methyltransferase activity* nucleus* S000000559 YDL127W=D <= STE12=D TEC1=D ac YDL127W PCL2 927 cell cycle cyclin-dependent protein kinase regulator activity cyclin-dependent protein kinase holoenzyme complex S000002285 YFL039C=D <= STE12=D TEC1=D a YFL039C ACT1 1436 cell wall organization and biogenesis* structural constituent of cytoskeleton* actin cortical patch* S000001855 YGR189C=D <= STE12=D TEC1=D a YGR189C CRH1 1524 biological_process unknown molecular_function unknown cell wall (sensu Fungi)* S000003421 YIL123W=D <= STE12=I TEC1=I c YIL123W SIM1 1428 microtubule cytoskeleton organization and biogenesis molecular_function unknown cell wall (sensu Fungi) S000001385 YKL096W=D <= STE12=I TEC1=I c YKL096W CWP1 720 cell wall organization and biogenesis structural constituent of cell wall cell wall (sensu Fungi) S000001579 YKL104C=D <= STE12=D TEC1=D a YKL104C GFA1 2154 cell wall chitin biosynthesis glutamine-fructose-6-phosphate transaminase (isomerizing) activity cellular_component unknown S000001587 YLR413W=D <= STE12=D TEC1=D ac YLR413W 2028 biological_process unknown molecular_function unknown cellular_component unknown S000004405 YLR452C=D <= STE12=D TEC1=D ac YLR452C SST2 2097 signal transduction* GTPase activator activity plasma membrane S000004444 YOL105C=D <= STE12=D TEC1=D a YOL105C WSC3 1671 cell wall organization and biogenesis* transmembrane receptor activity membrane fraction S000005465 YOR092W=D <= STE12=D TEC1=D a YOR092W ECM3 1842 cell wall organization and biogenesis ATPase activity endoplasmic reticulum S000005618 YOR127W=D <= STE12=D TEC1=D a YOR127W RGA1 3024 actin filament organization* signal transducer activity* intracellular S000005653 YOR247W=D <= STE12=D TEC1=D a YOR247W SRL1 633 "nucleobase, nucleoside, nucleotide and nucleic acid metabolism" molecular_function unknown cytoplasm* S000005773 YPL163C=D <= STE12=D TEC1=D ab YPL163C SVS1 783 response to chemical substance molecular_function unknown cell wall (sensu Fungi)* S000006084 YPL163C=D <= STE12=I TEC1=D c YPL163C SVS1 783 response to chemical substance molecular_function unknown cell wall (sensu Fungi)* S000006084 RCS1 HSF1 4 (3) YDR258C=D <= HSF1=D RCS1=D ab YDR258C HSP78 2436 response to stress* ATPase activity* mitochondrial matrix S000002666 YKR052C=D <= HSF1=D RCS1=D b YKR052C MRS4 915 transport* iron ion transporter activity* mitochondrion S000001760 YNR069C=D <= HSF1=D RCS1=I a YNR069C BSC5 1470 biological_process unknown molecular_function unknown cellular_component unknown S000005352 RCS1 NRG1 6 (5) YEL060C=D <= NRG1=D RCS1=D a YEL060C PRB1 1908 sporulation* serine-type endopeptidase activity vacuole (sensu Fungi) S000000786 YNR060W=D <= NRG1=I RCS1=I b YNR060W FRE4 2160 iron-siderochrome transport ferric-chelate reductase activity plasma membrane S000005343 YNR069C=D <= NRG1=D RCS1=D a YNR069C BSC5 1470 biological_process unknown molecular_function unknown cellular_component unknown S000005352 YNR070W=D <= NRG1=D RCS1=D a YNR070W 4002 transport "ATPase activity, coupled to transmembrane movement of substances" mitochondrion* S000005353 YNR070W=D <= NRG1=D RCS1=I a YNR070W 4002 transport "ATPase activity, coupled to transmembrane movement of substances" mitochondrion* S000005353 RCS1 AFT2 7 (7) YDR270W=D <= AFT2=D RCS1=D ab YDR270W CCC2 3015 intracellular copper ion transport* copper-exporting ATPase activity Golgi trans face S000002678 YER145C=D <= AFT2=I RCS1=D ab YER145C FTR1 1215 high affinity iron ion transport iron ion transporter activity plasma membrane S000000947 YER146W=D <= AFT2=I RCS1=D a YER146W LSM5 282 "nuclear mRNA splicing, via spliceosome*" pre-mRNA splicing factor activity small nuclear ribonucleoprotein complex S000000948 YLR205C=D <= AFT2=D RCS1=D ab YLR205C HMX1 954 iron ion homeostasis* heme binding* endoplasmic reticulum* S000004195 YOR384W=D <= AFT2=D RCS1=D b YOR384W FRE5 2085 biological_process unknown ferric-chelate reductase activity mitochondrion S000005911 YPL135W=D <= AFT2=D RCS1=D b YPL135W ISU1 498 iron ion homeostasis* protein binding mitochondrion* S000006056 YPR151C=D <= AFT2=D RCS1=D b YPR151C SUE1 621 protein catabolism molecular_function unknown mitochondrial membrane S000006355 SWI5 STE12 4 (3) YBR082C=D <= STE12=D SWI5=D a YBR082C UBC4 542 response to stress* ubiquitin conjugating enzyme activity proteasome complex (sensu Eukaryota) S000000286 YGL028C=D <= STE12=D SWI5=D abc YGL028C SCW11 1629 "cytokinesis, completion of separation" "glucan 1,3-beta-glucosidase activity" cell wall (sensu Fungi) S000002996 YGR189C=D <= STE12=D SWI5=I ac YGR189C CRH1 1524 biological_process unknown molecular_function unknown cell wall (sensu Fungi)* S000003421 SWI5 DIG1 5 (4) YDL127W=D <= DIG1=D SWI5=I c YDL127W PCL2 927 cell cycle cyclin-dependent protein kinase regulator activity cyclin-dependent protein kinase holoenzyme complex S000002285 YKL043W=D <= DIG1=D SWI5=I b YKL043W PHD1 1101 pseudohyphal growth specific RNA polymerase II transcription factor activity nucleus S000001526 YKL043W=D <= DIG1=I SWI5=D c YKL043W PHD1 1101 pseudohyphal growth specific RNA polymerase II transcription factor activity nucleus S000001526 YNL160W=D <= DIG1=D SWI5=I b YNL160W YGP1 1065 response to stress* molecular_function unknown cell wall (sensu Fungi) S000005104 SWI5 SWI6 5 (5) YDL127W=D <= SWI5=I SWI6=D c YDL127W PCL2 927 cell cycle cyclin-dependent protein kinase regulator activity cyclin-dependent protein kinase holoenzyme complex S000002285 YFR017C=D <= SWI5=I SWI6=I ac YFR017C 588 biological_process unknown molecular_function unknown cytoplasm S000001913 YGR041W=D <= SWI5=I SWI6=I c YGR041W BUD9 1644 bud site selection molecular_function unknown bud neck S000003273 YGR189C=D <= SWI5=I SWI6=D c YGR189C CRH1 1524 biological_process unknown molecular_function unknown cell wall (sensu Fungi)* S000003421 YLR300W=D <= SWI5=I SWI6=D a YLR300W EXG1 1347 cell wall organization and biogenesis* "glucan 1,3-beta-glucosidase activity" cell wall (sensu Fungi) S000004291 SWI5 REB1 5 (5) YDL226C=D <= REB1=D SWI5=D b YDL226C GCS1 1059 ER to Golgi transport* actin binding* cytoskeleton* S000002385 YNL078W=D <= REB1=D SWI5=D b YNL078W NIS1 1224 regulation of mitosis molecular_function unknown nucleus* S000005022 YNL078W=D <= REB1=D SWI5=I b YNL078W NIS1 1224 regulation of mitosis molecular_function unknown nucleus* S000005022 YNL078W=D <= REB1=I SWI5=I c YNL078W NIS1 1224 regulation of mitosis molecular_function unknown nucleus* S000005022 YNL079C=D <= REB1=D SWI5=D a YNL079C TPM1 600 actin filament organization* actin lateral binding contractile ring (sensu Saccharomyces)* S000005023 SWI5 AFT2 8 (6) YDL035C=D <= AFT2=D SWI5=D b YDL035C GPR1 2886 pseudohyphal growth* G-protein coupled receptor activity plasma membrane S000002193 YDR156W=D <= AFT2=I SWI5=D b YDR156W RPA14 414 transcription from Pol I promoter DNA-directed RNA polymerase activity DNA-directed RNA polymerase I complex S000002563 YFR017C=D <= AFT2=D SWI5=I a YFR017C 588 biological_process unknown molecular_function unknown cytoplasm S000001913 YFR017C=D <= AFT2=I SWI5=I b YFR017C 588 biological_process unknown molecular_function unknown cytoplasm S000001913 YML100W=D <= AFT2=D SWI5=I b YML100W TSL1 3297 response to stress* enzyme regulator activity "alpha,alpha-trehalose-phosphate synthase complex (UDP-forming)" S000004566 YML101C=D <= AFT2=I SWI5=I b YML101C CUE4 354 biological_process unknown molecular_function unknown cytoplasm* S000004568 MOT3 NRG1 4 (3) YAL060W=D <= MOT3=D NRG1=D ac YAL060W BDH1 1149 butanediol fermentation "(R,R)-butanediol dehydrogenase activity" cytoplasm S000000056 YKL109W=D <= MOT3=D NRG1=D ab YKL109W HAP4 1665 transcription* transcriptional activator activity CCAAT-binding factor complex S000001592 YPR149W=D <= MOT3=D NRG1=D ab YPR149W NCE102 522 protein secretion molecular_function unknown cytoplasm* S000006353 MOT3 HSF1 4 (4) YBR101C=D <= HSF1=D MOT3=D ac YBR101C FES1 873 protein biosynthesis adenyl-nucleotide exchange factor activity cytosol* S000000305 YER150W=D <= HSF1=D MOT3=D ab YER150W SPI1 447 biological_process unknown molecular_function unknown cell wall (sensu Fungi) S000000952 YGR142W=D <= HSF1=D MOT3=D a YGR142W BTN2 1233 intracellular protein transport* molecular_function unknown cytosol S000003374 YPR154W=D <= HSF1=D MOT3=D ab YPR154W PIN3 648 actin cytoskeleton organization and biogenesis molecular_function unknown cytoplasm* S000006358 MOT3 PHD1 6 (6) YHL028W=D <= MOT3=D PHD1=I c YHL028W WSC4 1818 cell wall organization and biogenesis* transmembrane receptor activity endoplasmic reticulum membrane* S000001020 YKL109W=D <= MOT3=D PHD1=D a YKL109W HAP4 1665 transcription* transcriptional activator activity CCAAT-binding factor complex S000001592 YMR017W=D <= MOT3=I PHD1=I bc YMR017W SPO20 1194 vesicle fusion* t-SNARE activity prospore membrane S000004619 YOR178C=D <= MOT3=D PHD1=D ac YOR178C GAC1 2382 meiosis* protein phosphatase type 1 activity* protein phosphatase type 1 complex S000005704 YOR178C=D <= MOT3=I PHD1=D a YOR178C GAC1 2382 meiosis* protein phosphatase type 1 activity* protein phosphatase type 1 complex S000005704 YPR065W=D <= MOT3=D PHD1=D ab YPR065W ROX1 1107 negative regulation of transcription from Pol II promoter specific transcriptional repressor activity* nuclear chromosome S000006269 MOT3 MSN4 6 (5) YAL003W=D <= MOT3=I MSN4=I abc YAL003W EFB1 987 translational elongation translation elongation factor activity ribosome S000000003 YAL005C=D <= MOT3=I MSN4=I bc YAL005C SSA1 1929 protein folding* ATPase activity* cytoplasm* S000000004 YAL060W=D <= MOT3=D MSN4=D a YAL060W BDH1 1149 butanediol fermentation "(R,R)-butanediol dehydrogenase activity" cytoplasm S000000056 YJL164C=D <= MOT3=D MSN4=D ab YJL164C TPK1 1194 protein amino acid phosphorylation* protein serine/threonine kinase activity* cytoplasm* S000003700 YKL103C=D <= MOT3=D MSN4=D abc YKL103C LAP4 1545 vacuolar protein catabolism aminopeptidase I activity vacuole (sensu Fungi) S000001586 MOT3 CIN5 6 (6) YLR304C=D <= CIN5=D MOT3=D a YLR304C ACO1 2337 tricarboxylic acid cycle* aconitate hydratase activity cytosol* S000004295 YOL109W=D <= CIN5=I MOT3=I b YOL109W ZEO1 342 cell wall organization and biogenesis* molecular_function unknown mitochondrion* S000005469 YOR178C=D <= CIN5=D MOT3=D ac YOR178C GAC1 2382 meiosis* protein phosphatase type 1 activity* protein phosphatase type 1 complex S000005704 YPR148C=D <= CIN5=D MOT3=D b YPR148C 1308 biological_process unknown molecular_function unknown cytoplasm S000006352 YPR149W=D <= CIN5=D MOT3=D a YPR149W NCE102 522 protein secretion molecular_function unknown cytoplasm* S000006353 YPR184W=D <= CIN5=D MOT3=D ab YPR184W GDB1 4611 glycogen catabolism 4-alpha-glucanotransferase activity* cytoplasm* S000006388 MOT3 SOK2 7 (6) YDR077W=D <= MOT3=D SOK2=D abc YDR077W SED1 1017 cell wall organization and biogenesis structural constituent of cell wall cell wall (sensu Fungi)* S000002484 YDR259C=D <= MOT3=D SOK2=I a YDR259C YAP6 1152 positive regulation of transcription from Pol II promoter RNA polymerase II transcription factor activity nucleus S000002667 YKL110C=D <= MOT3=I SOK2=I a YKL110C KTI12 942 carbon utilization enzyme regulator activity "DNA-directed RNA polymerase II, holoenzyme" S000001593 YMR017W=D <= MOT3=D SOK2=D a YMR017W SPO20 1194 vesicle fusion* t-SNARE activity prospore membrane S000004619 YMR017W=D <= MOT3=I SOK2=I b YMR017W SPO20 1194 vesicle fusion* t-SNARE activity prospore membrane S000004619 YOR178C=D <= MOT3=D SOK2=D a YOR178C GAC1 2382 meiosis* protein phosphatase type 1 activity* protein phosphatase type 1 complex S000005704 RPN4 CBF1 4 (2) YCR093W=D <= CBF1=I RPN4=I b YCR093W CDC39 6327 regulation of transcription from Pol II promoter* 3'-5'-exoribonuclease activity cytoplasm* S000000689 YFL023W=D <= CBF1=D RPN4=I b YFL023W BUD27 2391 bud site selection molecular_function unknown cytoplasm S000001871 RPN4 HSF1 5 (5) YGR142W=D <= HSF1=D RPN4=D ab YGR142W BTN2 1233 intracellular protein transport* molecular_function unknown cytosol S000003374 YLL039C=D <= HSF1=D RPN4=D ab YLL039C UBI4 1146 response to stress* ATP-dependent protein binding cytoplasm S000003962 YLR259C=D <= HSF1=D RPN4=D ab YLR259C HSP60 1719 protein folding* single-stranded DNA binding mitochondrion S000004249 YLR260W=D <= HSF1=D RPN4=D b YLR260W LCB5 2064 response to heat* D-erythro-sphingosine kinase activity membrane fraction* S000004250 YOR052C=D <= HSF1=D RPN4=D ab YOR052C 453 biological_process unknown molecular_function unknown nucleus S000005578 RPN4 YAP7 5 (3) YFL055W=D <= RPN4=D YAP7=D a YFL055W AGP3 1677 amino acid transport amino acid transporter activity plasma membrane S000001839 YFL055W=D <= RPN4=D YAP7=I a YFL055W AGP3 1677 amino acid transport amino acid transporter activity plasma membrane S000001839 YFL056C=D <= RPN4=D YAP7=D a YFL056C AAD6 639 aldehyde metabolism aryl-alcohol dehydrogenase activity cellular_component unknown S000001838 RPN4 REB1 8 (7) YBR170C=D <= REB1=D RPN4=D a YBR170C NPL4 1743 ER-associated protein catabolism molecular_function unknown endoplasmic reticulum* S000000374 YFL023W=D <= REB1=D RPN4=I ab YFL023W BUD27 2391 bud site selection molecular_function unknown cytoplasm S000001871 YFR052W=D <= REB1=D RPN4=D ab YFR052W RPN12 825 ubiquitin-dependent protein catabolism endopeptidase activity proteasome regulatory particle (sensu Eukaryota) S000001948 YFR052W=D <= REB1=D RPN4=I a YFR052W RPN12 825 ubiquitin-dependent protein catabolism endopeptidase activity proteasome regulatory particle (sensu Eukaryota) S000001948 YGR135W=D <= REB1=D RPN4=D ab YGR135W PRE9 777 ubiquitin-dependent protein catabolism* endopeptidase activity "proteasome core complex, alpha-subunit complex (sensu Eukaryota)" S000003367 YJL001W=D <= REB1=D RPN4=D ab YJL001W PRE3 764 ubiquitin-dependent protein catabolism* endopeptidase activity "proteasome core complex, beta-subunit complex (sensu Eukaryota)" S000003538 YOR158W=D <= REB1=D RPN4=I a YOR158W PET123 957 protein biosynthesis structural constituent of ribosome mitochondrial small ribosomal subunit S000005684 DAL82 GCN4 8 (8) YDL170W=D <= DAL82=D GCN4=D a YDL170W UGA3 1587 regulation of transcription from Pol II promoter* specific RNA polymerase II transcription factor activity nucleus S000002329 YJR152W=D <= DAL82=D GCN4=D a YJR152W DAL5 1632 allantoate transport allantoate transporter activity plasma membrane S000003913 YMR251W-A=D <= DAL82=I GCN4=I ab YMR251W-A HOR7 180 response to stress molecular_function unknown endoplasmic reticulum* S000004864 YOL020W=D <= DAL82=I GCN4=I a YOL020W TAT2 1779 aromatic amino acid transport aromatic amino acid transporter activity plasma membrane S000005380 YOL021C=D <= DAL82=I GCN4=D a YOL021C DIS3 3006 35S primary transcript processing* 3'-5'-exoribonuclease activity mitochondrion* S000005381 YOL152W=D <= DAL82=D GCN4=D ab YOL152W FRE7 1890 biological_process unknown ferric-chelate reductase activity cellular_component unknown S000005512 YOL152W=D <= DAL82=D GCN4=I ab YOL152W FRE7 1890 biological_process unknown ferric-chelate reductase activity cellular_component unknown S000005512 YPR145W=D <= DAL82=I GCN4=I a YPR145W ASN1 1719 asparagine biosynthesis asparagine synthase (glutamine-hydrolyzing) activity cytoplasm S000006349 DAL82 GLN3 13 (12) YDL170W=D <= DAL82=D GLN3=D a YDL170W UGA3 1587 regulation of transcription from Pol II promoter* specific RNA polymerase II transcription factor activity nucleus S000002329 YIR027C=D <= DAL82=D GLN3=D a YIR027C DAL1 1383 allantoin catabolism allantoinase activity intracellular S000001466 YIR028W=D <= DAL82=D GLN3=D a YIR028W DAL4 1908 allantoin transport allantoin permease activity membrane S000001467 YIR029W=D <= DAL82=D GLN3=D a YIR029W DAL2 1032 allantoin catabolism allantoicase activity cellular_component unknown S000001468 YIR029W=D <= DAL82=I GLN3=I b YIR029W DAL2 1032 allantoin catabolism allantoicase activity cellular_component unknown S000001468 YIR030C=D <= DAL82=D GLN3=D a YIR030C DCG1 735 nitrogen compound metabolism molecular_function unknown cellular_component unknown S000001469 YIR031C=D <= DAL82=D GLN3=D a YIR031C DAL7 1665 allantoin catabolism malate synthase activity cytoplasm S000001470 YIR033W=D <= DAL82=D GLN3=D b YIR033W MGA2 3342 positive regulation of transcription from Pol II promoter* transcriptional activator activity endoplasmic reticulum membrane S000001472 YJR011C=D <= DAL82=D GLN3=D a YJR011C 786 biological_process unknown molecular_function unknown cellular_component unknown S000003772 YJR152W=D <= DAL82=D GLN3=D a YJR152W DAL5 1632 allantoate transport allantoate transporter activity plasma membrane S000003913 YOR375C=D <= DAL82=I GLN3=I a YOR375C GDH1 1365 glutamate biosynthesis glutamate dehydrogenase (NADP+) activity cytoplasm* S000005902 YPR145W=D <= DAL82=I GLN3=I a YPR145W ASN1 1719 asparagine biosynthesis asparagine synthase (glutamine-hydrolyzing) activity cytoplasm S000006349 GLN3 CIN5 5 (5) YCL025C=D <= CIN5=D GLN3=D b YCL025C AGP1 1788 amino acid transport amino acid transporter activity plasma membrane S000000530 YCL025C=D <= CIN5=I GLN3=D b YCL025C AGP1 1788 amino acid transport amino acid transporter activity plasma membrane S000000530 YKR039W=D <= CIN5=I GLN3=D a YKR039W GAP1 1809 amino acid transport amino acid permease activity integral to plasma membrane S000001747 YOL109W=D <= CIN5=D GLN3=I b YOL109W ZEO1 342 cell wall organization and biogenesis* molecular_function unknown mitochondrion* S000005469 YOL109W=D <= CIN5=I GLN3=I b YOL109W ZEO1 342 cell wall organization and biogenesis* molecular_function unknown mitochondrion* S000005469 GLN3 GCN4 7 (6) YDL170W=D <= GCN4=D GLN3=D a YDL170W UGA3 1587 regulation of transcription from Pol II promoter* specific RNA polymerase II transcription factor activity nucleus S000002329 YEL063C=D <= GCN4=D GLN3=D a YEL063C CAN1 1773 basic amino acid transport basic amino acid transporter activity* mitochondrion* S000000789 YHR006W=D <= GCN4=D GLN3=D a YHR006W STP2 1626 positive regulation of transcription from Pol II promoter specific RNA polymerase II transcription factor activity nucleus S000001048 YHR029C=D <= GCN4=D GLN3=D a YHR029C 885 biological_process unknown molecular_function unknown cellular_component unknown S000001071 YNR069C=D <= GCN4=D GLN3=D a YNR069C BSC5 1470 biological_process unknown molecular_function unknown cellular_component unknown S000005352 YOL119C=D <= GCN4=D GLN3=D a YOL119C MCH4 1506 transport transporter activity* vacuolar membrane (sensu Fungi) S000005479 FKH2 SWI6 4 (1) YLR300W=D <= FKH2=D SWI6=D a YLR300W EXG1 1347 cell wall organization and biogenesis* "glucan 1,3-beta-glucosidase activity" cell wall (sensu Fungi) S000004291 FKH2 STE12 5 (2) YCL054W=D <= FKH2=D STE12=D abc YCL054W SPB1 2526 processing of 27S pre-rRNA S-adenosylmethionine-dependent methyltransferase activity* nucleus* S000000559 YGL028C=D <= FKH2=D STE12=D ac YGL028C SCW11 1629 "cytokinesis, completion of separation" "glucan 1,3-beta-glucosidase activity" cell wall (sensu Fungi) S000002996 FKH2 FKH1 9 (7) YBR009C=D <= FKH1=D FKH2=D a YBR009C HHF1 312 chromatin assembly or disassembly DNA binding nuclear nucleosome S000000213 YBR010W=D <= FKH1=D FKH2=D ac YBR010W HHT1 411 chromatin assembly or disassembly DNA binding nucleus* S000000214 YCL064C=D <= FKH1=D FKH2=D ac YCL064C CHA1 1083 threonine catabolism* L-serine ammonia-lyase activity* mitochondrion S000000569 YGR092W=D <= FKH1=D FKH2=D a YGR092W DBF2 1719 protein amino acid phosphorylation* protein serine/threonine kinase activity bud neck* S000003324 YLR257W=D <= FKH1=I FKH2=I b YLR257W 966 biological_process unknown molecular_function unknown cytoplasm S000004247 YMR117C=D <= FKH1=D FKH2=D a YMR117C SPC24 642 chromosome segregation* structural constituent of cytoskeleton condensed nuclear chromosome kinetochore* S000004723 YPL155C=D <= FKH1=D FKH2=D bc YPL155C KIP2 2121 "nuclear migration, microtubule-mediated*" microtubule motor activity mitochondrion* S000006076 SWI4 MBP1 5 (4) YGL178W=D <= MBP1=D SWI4=D ab YGL178W MPT5 3220 cell wall organization and biogenesis* mRNA binding cytoplasm S000003146 YKL007W=D <= MBP1=I SWI4=I b YKL007W CAP1 807 barbed-end actin filament capping actin filament binding actin cortical patch* S000001490 YKL103C=D <= MBP1=I SWI4=I bc YKL103C LAP4 1545 vacuolar protein catabolism aminopeptidase I activity vacuole (sensu Fungi) S000001586 YMR017W=D <= MBP1=D SWI4=I a YMR017W SPO20 1194 vesicle fusion* t-SNARE activity prospore membrane S000004619 SWI4 DIG1 5 (4) YIL123W=D <= DIG1=D SWI4=D ab YIL123W SIM1 1428 microtubule cytoskeleton organization and biogenesis molecular_function unknown cell wall (sensu Fungi) S000001385 YKL043W=D <= DIG1=I SWI4=I c YKL043W PHD1 1101 pseudohyphal growth specific RNA polymerase II transcription factor activity nucleus S000001526 YKL096W=D <= DIG1=D SWI4=D ab YKL096W CWP1 720 cell wall organization and biogenesis structural constituent of cell wall cell wall (sensu Fungi) S000001579 YNL298W=D <= DIG1=D SWI4=D b YNL298W CLA4 2529 protein amino acid phosphorylation* protein serine/threonine kinase activity actin cap S000005242 SWI4 STE12 9 (5) YBR162C=D <= STE12=D SWI4=D ab YBR162C TOS1 1368 biological_process unknown molecular_function unknown cell wall (sensu Fungi)* S000000366 YGR189C=D <= STE12=D SWI4=D ac YGR189C CRH1 1524 biological_process unknown molecular_function unknown cell wall (sensu Fungi)* S000003421 YJR054W=D <= STE12=D SWI4=D ac YJR054W 1494 biological_process unknown molecular_function unknown vacuole (sensu Fungi) S000003815 YPL163C=D <= STE12=D SWI4=D abc YPL163C SVS1 783 response to chemical substance molecular_function unknown cell wall (sensu Fungi)* S000006084 YPL163C=D <= STE12=D SWI4=I a YPL163C SVS1 783 response to chemical substance molecular_function unknown cell wall (sensu Fungi)* S000006084 SWI4 STE12 SWI6 4 (4) YGR189C=D <= STE12=D SWI4=D SWI6=D a YGR189C CRH1 1524 biological_process unknown molecular_function unknown cell wall (sensu Fungi)* S000003421 YIL123W=D <= STE12=D SWI4=D SWI6=D ab YIL123W SIM1 1428 microtubule cytoskeleton organization and biogenesis molecular_function unknown cell wall (sensu Fungi) S000001385 YJR054W=D <= STE12=D SWI4=D SWI6=D a YJR054W 1494 biological_process unknown molecular_function unknown vacuole (sensu Fungi) S000003815 YPL163C=D <= STE12=D SWI4=D SWI6=D ab YPL163C SVS1 783 response to chemical substance molecular_function unknown cell wall (sensu Fungi)* S000006084 SWI4 SWI6 25 (16) YDL227C=D <= SWI4=D SWI6=D b YDL227C HO 1761 mating type switching and recombination* endonuclease activity nucleus S000002386 YGL178W=D <= SWI4=D SWI6=D ab YGL178W MPT5 3220 cell wall organization and biogenesis* mRNA binding cytoplasm S000003146 YGL179C=D <= SWI4=I SWI6=I b YGL179C TOS3 1683 glucose metabolism protein kinase activity cytoplasm S000003147 YGR152C=D <= SWI4=D SWI6=D ac YGR152C RSR1 819 bipolar bud site selection* GTPase activity* plasma membrane* S000003384 YGR153W=D <= SWI4=I SWI6=I b YGR153W 654 biological_process unknown molecular_function unknown cellular_component unknown S000003385 YGR279C=D <= SWI4=D SWI6=D b YGR279C SCW4 1161 conjugation with cellular fusion glucosidase activity cell wall (sensu Fungi) S000003511 YHR149C=D <= SWI4=D SWI6=D ac YHR149C SKG6 2205 biological_process unknown molecular_function unknown bud neck* S000001192 YHR150W=D <= SWI4=I SWI6=I ab YHR150W PEX28 1740 peroxisome organization and biogenesis molecular_function unknown peroxisomal membrane S000001193 YJL186W=D <= SWI4=D SWI6=D b YJL186W MNN5 1761 protein amino acid glycosylation "alpha-1,2-mannosyltransferase activity" Golgi apparatus S000003722 YJR054W=D <= SWI4=D SWI6=D ac YJR054W 1494 biological_process unknown molecular_function unknown vacuole (sensu Fungi) S000003815 YKL008C=D <= SWI4=D SWI6=D a YKL008C LAC1 1257 ceramide biosynthesis* sphingosine N-acyltransferase activity endoplasmic reticulum S000001491 YLR056W=D <= SWI4=D SWI6=D ab YLR056W ERG3 1098 ergosterol biosynthesis C-5 sterol desaturase activity endoplasmic reticulum S000004046 YMR017W=D <= SWI4=I SWI6=I a YMR017W SPO20 1194 vesicle fusion* t-SNARE activity prospore membrane S000004619 YMR307W=D <= SWI4=D SWI6=D ab YMR307W GAS1 1680 cell wall organization and biogenesis "1,3-beta-glucanosyltransferase activity" mitochondrion* S000004924 YNL231C=D <= SWI4=D SWI6=D ac YNL231C PDR16 1056 response to drug* phosphatidylinositol transporter activity cytoplasm* S000005175 YPR009W=D <= SWI4=D SWI6=D a YPR009W SUT2 807 regulation of transcription from Pol II promoter* specific RNA polymerase II transcription factor activity nucleus S000006213 PHD1 CIN5 4 (2) YKL110C=D <= CIN5=I PHD1=I b YKL110C KTI12 942 carbon utilization enzyme regulator activity "DNA-directed RNA polymerase II, holoenzyme" S000001593 YOR178C=D <= CIN5=D PHD1=D ab YOR178C GAC1 2382 meiosis* protein phosphatase type 1 activity* protein phosphatase type 1 complex S000005704 PHD1 AFT2 4 (4) YBR068C=D <= AFT2=I PHD1=I a YBR068C BAP2 1830 amino acid transport amino acid transporter activity plasma membrane S000000272 YER145C=D <= AFT2=I PHD1=D c YER145C FTR1 1215 high affinity iron ion transport iron ion transporter activity plasma membrane S000000947 YMR015C=D <= AFT2=D PHD1=I b YMR015C ERG5 1617 ergosterol biosynthesis C-22 sterol desaturase activity endoplasmic reticulum S000004617 YMR015C=D <= AFT2=I PHD1=D ac YMR015C ERG5 1617 ergosterol biosynthesis C-22 sterol desaturase activity endoplasmic reticulum S000004617 PHD1 MBP1 5 (3) YGR138C=D <= MBP1=I PHD1=I b YGR138C TPO2 1845 polyamine transport spermine transporter activity plasma membrane* S000003370 YPL014W=D <= MBP1=I PHD1=I b YPL014W 1146 biological_process unknown molecular_function unknown cytoplasm* S000005935 YPL015C=D <= MBP1=I PHD1=I b YPL015C HST2 1074 chromatin silencing at telomere NAD-dependent histone deacetylase activity cytoplasm S000005936 PHD1 CBF1 5 (3) YER046W=D <= CBF1=D PHD1=D a YER046W SPO73 432 sporulation (sensu Fungi) molecular_function unknown cellular_component unknown S000000848 YHR137W=D <= CBF1=D PHD1=D b YHR137W ARO9 1542 aromatic amino acid family metabolism aromatic-amino-acid transaminase activity cytoplasm* S000001179 YMR195W=D <= CBF1=D PHD1=D b YMR195W ICY1 384 biological_process unknown molecular_function unknown vacuolar membrane (sensu Fungi) S000004808 PHD1 SOK2 10 (4) YGR138C=D <= PHD1=I SOK2=I b YGR138C TPO2 1845 polyamine transport spermine transporter activity plasma membrane* S000003370 YGR279C=D <= PHD1=I SOK2=D b YGR279C SCW4 1161 conjugation with cellular fusion glucosidase activity cell wall (sensu Fungi) S000003511 YIL056W=D <= PHD1=D SOK2=D b YIL056W 1923 biological_process unknown molecular_function unknown cytoplasm* S000001318 YKL109W=D <= PHD1=I SOK2=I b YKL109W HAP4 1665 transcription* transcriptional activator activity CCAAT-binding factor complex S000001592 PHD1 NRG1 14 (8) YBR067C=D <= NRG1=D PHD1=D bc YBR067C TIP1 633 cell wall organization and biogenesis structural constituent of cell wall* cell wall (sensu Fungi) S000000271 YBR069C=D <= NRG1=I PHD1=I ab YBR069C TAT1 1860 amino acid transport amino acid transporter activity plasma membrane S000000273 YER145C=D <= NRG1=I PHD1=I ab YER145C FTR1 1215 high affinity iron ion transport iron ion transporter activity plasma membrane S000000947 YKL109W=D <= NRG1=D PHD1=I ab YKL109W HAP4 1665 transcription* transcriptional activator activity CCAAT-binding factor complex S000001592 YMR195W=D <= NRG1=D PHD1=D ab YMR195W ICY1 384 biological_process unknown molecular_function unknown vacuolar membrane (sensu Fungi) S000004808 YPL058C=D <= NRG1=I PHD1=I b YPL058C PDR12 4536 transport* xenobiotic-transporting ATPase activity* plasma membrane S000005979 YPL230W=D <= NRG1=D PHD1=D ab YPL230W 1176 biological_process unknown molecular_function unknown cellular_component unknown S000006151 YPL265W=D <= NRG1=D PHD1=D bc YPL265W DIP5 1827 amino acid transport amino acid transporter activity* plasma membrane S000006186 SOK2 FKH1 6 (5) YDR259C=D <= FKH1=I SOK2=I a YDR259C YAP6 1152 positive regulation of transcription from Pol II promoter RNA polymerase II transcription factor activity nucleus S000002667 YGR108W=D <= FKH1=D SOK2=D bc YGR108W CLB1 1416 G2/M transition of mitotic cell cycle* cyclin-dependent protein kinase regulator activity nucleus S000003340 YJR094C=D <= FKH1=I SOK2=D a YJR094C IME1 1083 meiosis transcription regulator activity nucleus S000003854 YJR094W-A=D <= FKH1=D SOK2=D ab YJR094W-A RPL43B 554 protein biosynthesis structural constituent of ribosome cytosolic large ribosomal subunit (sensu Eukaryota) S000003855 YJR094W-A=D <= FKH1=D SOK2=I a YJR094W-A RPL43B 554 protein biosynthesis structural constituent of ribosome cytosolic large ribosomal subunit (sensu Eukaryota) S000003855 SOK2 STE12 6 (5) YLR413W=D <= SOK2=D STE12=D ab YLR413W 2028 biological_process unknown molecular_function unknown cellular_component unknown S000004405 YLR413W=D <= SOK2=I STE12=D ac YLR413W 2028 biological_process unknown molecular_function unknown cellular_component unknown S000004405 YMR305C=D <= SOK2=D STE12=D a YMR305C SCW10 1170 conjugation with cellular fusion glucosidase activity cytoplasm* S000004921 YMR305C=D <= SOK2=I STE12=D a YMR305C SCW10 1170 conjugation with cellular fusion glucosidase activity cytoplasm* S000004921 YPL177C=D <= SOK2=I STE12=D a YPL177C CUP9 921 transcription initiation from Pol II promoter* specific RNA polymerase II transcription factor activity nucleus S000006098 SOK2 NRG1 10 (5) YDL049C=D <= NRG1=D SOK2=D a YDL049C KNH1 807 "beta-1,6 glucan biosynthesis" molecular_function unknown cell wall (sensu Fungi)* S000002207 YKR102W=D <= NRG1=D SOK2=D a YKR102W FLO10 3510 flocculation (sensu Saccharomyces) mannose binding cell wall (sensu Fungi) S000001810 YOR030W=D <= NRG1=D SOK2=D a YOR030W DFG16 1860 invasive growth (sensu Saccharomyces) molecular_function unknown cellular_component unknown S000005556 YPL026C=D <= NRG1=D SOK2=D a YPL026C SKS1 1509 protein amino acid phosphorylation* protein serine/threonine kinase activity cytoplasm S000005947 YPL230W=D <= NRG1=D SOK2=D a YPL230W 1176 biological_process unknown molecular_function unknown cellular_component unknown S000006151 SOK2 CIN5 12 (8) YGR108W=D <= CIN5=I SOK2=I a YGR108W CLB1 1416 G2/M transition of mitotic cell cycle* cyclin-dependent protein kinase regulator activity nucleus S000003340 YJR094C=D <= CIN5=D SOK2=D a YJR094C IME1 1083 meiosis transcription regulator activity nucleus S000003854 YKL043W=D <= CIN5=D SOK2=D bc YKL043W PHD1 1101 pseudohyphal growth specific RNA polymerase II transcription factor activity nucleus S000001526 YKR102W=D <= CIN5=D SOK2=D a YKR102W FLO10 3510 flocculation (sensu Saccharomyces) mannose binding cell wall (sensu Fungi) S000001810 YLR413W=D <= CIN5=I SOK2=D ab YLR413W 2028 biological_process unknown molecular_function unknown cellular_component unknown S000004405 YMR017W=D <= CIN5=D SOK2=D a YMR017W SPO20 1194 vesicle fusion* t-SNARE activity prospore membrane S000004619 YOL109W=D <= CIN5=I SOK2=I abc YOL109W ZEO1 342 cell wall organization and biogenesis* molecular_function unknown mitochondrion* S000005469 YOR030W=D <= CIN5=D SOK2=D a YOR030W DFG16 1860 invasive growth (sensu Saccharomyces) molecular_function unknown cellular_component unknown S000005556 AFT2 CBF1 4 (3) YMR216C=D <= AFT2=I CBF1=D b YMR216C SKY1 2229 response to drug* protein kinase activity cytoplasm S000004829 YMR217W=D <= AFT2=I CBF1=D ab YMR217W GUA1 1578 GMP metabolism GMP synthase (glutamine-hydrolyzing) activity cellular_component unknown S000004830 YMR217W=D <= AFT2=I CBF1=I b YMR217W GUA1 1578 GMP metabolism GMP synthase (glutamine-hydrolyzing) activity cellular_component unknown S000004830 AFT2 SKN7 5 (4) YDR155C=D <= AFT2=I SKN7=I a YDR155C CPR1 489 protein metabolism peptidyl-prolyl cis-trans isomerase activity histone deacetylase complex S000002562 YNR018W=D <= AFT2=I SKN7=I a YNR018W 675 biological_process unknown molecular_function unknown mitochondrion S000005301 YOR226C=D <= AFT2=I SKN7=I b YOR226C ISU2 471 iron ion homeostasis* molecular_function unknown mitochondrial matrix S000005752 YPL135W=D <= AFT2=D SKN7=D a YPL135W ISU1 498 iron ion homeostasis* protein binding mitochondrion* S000006056 AFT2 NRG1 5 (5) YBR296C=D <= AFT2=I NRG1=D a YBR296C PHO89 1725 phosphate transport sodium:inorganic phosphate symporter activity plasma membrane S000000500 YBR296C=D <= AFT2=I NRG1=I b YBR296C PHO89 1725 phosphate transport sodium:inorganic phosphate symporter activity plasma membrane S000000500 YBR297W=D <= AFT2=I NRG1=D a YBR297W MAL33 1407 "regulation of transcription, DNA-dependent*" transcription factor activity nucleus S000000501 YEL060C=D <= AFT2=I NRG1=D a YEL060C PRB1 1908 sporulation* serine-type endopeptidase activity vacuole (sensu Fungi) S000000786 YOR226C=D <= AFT2=I NRG1=I b YOR226C ISU2 471 iron ion homeostasis* molecular_function unknown mitochondrial matrix S000005752 AFT2 GCN4 6 (5) YBR068C=D <= AFT2=I GCN4=I a YBR068C BAP2 1830 amino acid transport amino acid transporter activity plasma membrane S000000272 YJL212C=D <= AFT2=D GCN4=D a YJL212C OPT1 2400 sulfur metabolism oligopeptide transporter activity endoplasmic reticulum* S000003748 YKL101W=D <= AFT2=I GCN4=I a YKL101W HSL1 4557 protein amino acid phosphorylation* protein kinase activity bud neck* S000001584 YNR009W=D <= AFT2=I GCN4=D b YNR009W 750 biological_process unknown molecular_function unknown cytoplasm* S000005292 YPL135W=D <= AFT2=D GCN4=I a YPL135W ISU1 498 iron ion homeostasis* protein binding mitochondrion* S000006056 AFT2 RAP1 6 (5) YJL133W=D <= AFT2=I RAP1=I b YJL133W MRS3 945 transport* iron ion transporter activity* mitochondrion S000003669 YLR340W=D <= AFT2=I RAP1=D ab YLR340W RPP0 939 translational elongation* structural constituent of ribosome cytosolic large ribosomal subunit (sensu Eukaryota) S000004332 YMR015C=D <= AFT2=D RAP1=D b YMR015C ERG5 1617 ergosterol biosynthesis C-22 sterol desaturase activity endoplasmic reticulum S000004617 YMR265C=D <= AFT2=I RAP1=D b YMR265C 1386 biological_process unknown molecular_function unknown cellular_component unknown S000004878 YMR265C=D <= AFT2=I RAP1=I b YMR265C 1386 biological_process unknown molecular_function unknown cellular_component unknown S000004878 AFT2 HSF1 8 (7) YDR155C=D <= AFT2=D HSF1=D b YDR155C CPR1 489 protein metabolism peptidyl-prolyl cis-trans isomerase activity histone deacetylase complex S000002562 YDR156W=D <= AFT2=I HSF1=I b YDR156W RPA14 414 transcription from Pol I promoter DNA-directed RNA polymerase activity DNA-directed RNA polymerase I complex S000002563 YGL055W=D <= AFT2=I HSF1=I b YGL055W OLE1 1533 mitochondrion inheritance* stearoyl-CoA 9-desaturase activity endoplasmic reticulum membrane S000003023 YJL034W=D <= AFT2=D HSF1=D b YJL034W KAR2 2049 "SRP-dependent cotranslational protein-membrane targeting, translocation*" ATPase activity* endoplasmic reticulum lumen S000003571 YJL035C=D <= AFT2=D HSF1=D b YJL035C TAD2 753 tRNA modification tRNA specific adenosine deaminase activity cytoplasm* S000003572 YJR045C=D <= AFT2=D HSF1=D b YJR045C SSC1 1965 protein folding* ATPase activity* mitochondrion* S000003806 YKR052C=D <= AFT2=I HSF1=I b YKR052C MRS4 915 transport* iron ion transporter activity* mitochondrion S000001760 AFT2 MSN4 9 (8) YER177W=D <= AFT2=D MSN4=D b YER177W BMH1 804 sporulation (sensu Fungi)* protein binding* nucleus S000000979 YHR008C=D <= AFT2=D MSN4=I a YHR008C SOD2 702 replicative cell aging* manganese superoxide dismutase activity mitochondrion* S000001050 YKL101W=D <= AFT2=I MSN4=I a YKL101W HSL1 4557 protein amino acid phosphorylation* protein kinase activity bud neck* S000001584 YKL103C=D <= AFT2=D MSN4=D abc YKL103C LAP4 1545 vacuolar protein catabolism aminopeptidase I activity vacuole (sensu Fungi) S000001586 YML101C=D <= AFT2=I MSN4=I b YML101C CUE4 354 biological_process unknown molecular_function unknown cytoplasm* S000004568 YNL194C=D <= AFT2=D MSN4=D a YNL194C 906 biological_process unknown molecular_function unknown cytoplasm* S000005138 YNL194C=D <= AFT2=I MSN4=I bc YNL194C 906 biological_process unknown molecular_function unknown cytoplasm* S000005138 YNL241C=D <= AFT2=D MSN4=I a YNL241C ZWF1 1518 pentose-phosphate shunt glucose-6-phosphate 1-dehydrogenase activity cytoplasm S000005185 SKN7 MSN4 4 (3) YDR171W=D <= MSN4=D SKN7=I ab YDR171W HSP42 1128 response to stress* unfolded protein binding cytoplasm* S000002578 YOR018W=D <= MSN4=D SKN7=D b YOR018W ROD1 2514 response to drug molecular_function unknown plasma membrane S000005544 YOR226C=D <= MSN4=I SKN7=I b YOR226C ISU2 471 iron ion homeostasis* molecular_function unknown mitochondrial matrix S000005752 SKN7 YAP7 5 (5) YKL087C=D <= SKN7=I YAP7=D b YKL087C CYT2 675 cytochrome c-heme linkage holocytochrome-c synthase activity mitochondrial intermembrane space S000001570 YOL058W=D <= SKN7=D YAP7=D a YOL058W ARG1 1263 arginine biosynthesis* argininosuccinate synthase activity cytosol S000005419 YOL058W=D <= SKN7=I YAP7=I b YOL058W ARG1 1263 arginine biosynthesis* argininosuccinate synthase activity cytosol S000005419 YOR226C=D <= SKN7=I YAP7=I b YOR226C ISU2 471 iron ion homeostasis* molecular_function unknown mitochondrial matrix S000005752 YOR227W=D <= SKN7=I YAP7=I a YOR227W 3741 biological_process unknown molecular_function unknown cytoplasm* S000005753 SKN7 NRG1 7 (6) YDR403W=D <= NRG1=D SKN7=D ac YDR403W DIT1 1611 spore wall assembly (sensu Fungi) catalytic activity cellular_component unknown S000002811 YER011W=D <= NRG1=I SKN7=I b YER011W TIR1 765 response to stress structural constituent of cell wall cell wall (sensu Fungi) S000000813 YKR075C=D <= NRG1=D SKN7=D ab YKR075C 924 biological_process unknown molecular_function unknown cytoplasm* S000001783 YKR076W=D <= NRG1=I SKN7=I b YKR076W ECM4 1113 cell wall organization and biogenesis molecular_function unknown cytoplasm S000001784 YMR081C=D <= NRG1=D SKN7=I ab YMR081C ISF1 1017 aerobic respiration molecular_function unknown cellular_component unknown S000004686 YOR227W=D <= NRG1=D SKN7=D b YOR227W 3741 biological_process unknown molecular_function unknown cytoplasm* S000005753 SKN7 CIN5 9 (7) YBR054W=D <= CIN5=I SKN7=D c YBR054W YRO2 1035 biological_process unknown molecular_function unknown mitochondrion* S000000258 YBR054W=D <= CIN5=I SKN7=I ac YBR054W YRO2 1035 biological_process unknown molecular_function unknown mitochondrion* S000000258 YKL043W=D <= CIN5=D SKN7=D b YKL043W PHD1 1101 pseudohyphal growth specific RNA polymerase II transcription factor activity nucleus S000001526 YKL110C=D <= CIN5=I SKN7=I ab YKL110C KTI12 942 carbon utilization enzyme regulator activity "DNA-directed RNA polymerase II, holoenzyme" S000001593 YMR081C=D <= CIN5=D SKN7=D a YMR081C ISF1 1017 aerobic respiration molecular_function unknown cellular_component unknown S000004686 YMR081C=D <= CIN5=D SKN7=I a YMR081C ISF1 1017 aerobic respiration molecular_function unknown cellular_component unknown S000004686 YMR173W=D <= CIN5=I SKN7=I a YMR173W DDR48 1293 DNA repair ATPase activity* cytoplasm S000004784 DIG1 FKH1 4 (3) YAR014C=D <= DIG1=I FKH1=I a YAR014C BUD14 2124 cellular morphogenesis during vegetative growth molecular_function unknown bud neck* S000000069 YAR015W=D <= DIG1=D FKH1=D ab YAR015W ADE1 921 purine nucleotide biosynthesis* phosphoribosylaminoimidazolesuccinocarboxamide synthase activity cytoplasm* S000000070 YPL048W=D <= DIG1=D FKH1=D a YPL048W CAM1 1248 regulation of translational elongation translation elongation factor activity cytosolic ribosome (sensu Eukaryota) S000005969 DIG1 ABF1 4 (4) YBR011C=D <= ABF1=D DIG1=D ab YBR011C IPP1 864 phosphate metabolism inorganic diphosphatase activity cytosol S000000215 YMR197C=D <= ABF1=D DIG1=D a YMR197C VTI1 654 vesicle fusion* v-SNARE activity integral to Golgi membrane S000004810 YMR235C=D <= ABF1=D DIG1=D a YMR235C RNA1 1224 rRNA-nucleus export* Ran GTPase activator activity nucleus* S000004848 YNL322C=D <= ABF1=I DIG1=I a YNL322C KRE1 942 cell wall organization and biogenesis structural constituent of cell wall cell wall (sensu Fungi) S000005266 DIG1 MBP1 5 (3) YFL039C=D <= DIG1=D MBP1=I a YFL039C ACT1 1436 cell wall organization and biogenesis* structural constituent of cytoskeleton* actin cortical patch* S000001855 YGR189C=D <= DIG1=D MBP1=I ac YGR189C CRH1 1524 biological_process unknown molecular_function unknown cell wall (sensu Fungi)* S000003421 YOL082W=D <= DIG1=D MBP1=I b YOL082W ATG19 1248 protein-vacuolar targeting protein binding cytoplasm* S000005442 DIG1 SWI6 6 (5) YDR528W=D <= DIG1=D SWI6=D ac YDR528W HLR1 1272 cell wall organization and biogenesis molecular_function unknown cytoplasm S000002936 YGR189C=D <= DIG1=D SWI6=D ac YGR189C CRH1 1524 biological_process unknown molecular_function unknown cell wall (sensu Fungi)* S000003421 YIL123W=D <= DIG1=D SWI6=D ab YIL123W SIM1 1428 microtubule cytoskeleton organization and biogenesis molecular_function unknown cell wall (sensu Fungi) S000001385 YKL096W=D <= DIG1=D SWI6=D ab YKL096W CWP1 720 cell wall organization and biogenesis structural constituent of cell wall cell wall (sensu Fungi) S000001579 YKR013W=D <= DIG1=D SWI6=D abc YKR013W PRY2 990 biological_process unknown molecular_function unknown vacuole (sensu Fungi)* S000001721 DIG1 STE12 28 (23) YBR011C=D <= DIG1=D STE12=D ab YBR011C IPP1 864 phosphate metabolism inorganic diphosphatase activity cytosol S000000215 YBR040W=D <= DIG1=D STE12=D bc YBR040W FIG1 897 cellular morphogenesis during conjugation with cellular fusion* molecular_function unknown cell wall (sensu Fungi)* S000000244 YBR082C=D <= DIG1=D STE12=D ac YBR082C UBC4 542 response to stress* ubiquitin conjugating enzyme activity proteasome complex (sensu Eukaryota) S000000286 YBR082C=D <= DIG1=I STE12=I b YBR082C UBC4 542 response to stress* ubiquitin conjugating enzyme activity proteasome complex (sensu Eukaryota) S000000286 YCL055W=D <= DIG1=D STE12=D ac YCL055W KAR4 1008 meiosis* transcription regulator activity nucleus S000000560 YCL055W=D <= DIG1=I STE12=I b YCL055W KAR4 1008 meiosis* transcription regulator activity nucleus S000000560 YER189W=D <= DIG1=I STE12=I a YER189W 369 biological_process unknown molecular_function unknown cellular_component unknown S000000991 YFL026W=D <= DIG1=D STE12=D a YFL026W STE2 1296 response to pheromone during conjugation with cellular fusion* mating-type alpha-factor pheromone receptor activity integral to plasma membrane S000001868 YGL162W=D <= DIG1=D STE12=D b YGL162W SUT1 900 regulation of transcription from Pol II promoter* specific RNA polymerase II transcription factor activity nucleus S000003130 YGL163C=D <= DIG1=I STE12=I b YGL163C RAD54 2697 chromatin remodeling* DNA-dependent ATPase activity* nucleus S000003131 YIL123W=D <= DIG1=D STE12=D ab YIL123W SIM1 1428 microtubule cytoskeleton organization and biogenesis molecular_function unknown cell wall (sensu Fungi) S000001385 YJL148W=D <= DIG1=D STE12=D ac YJL148W RPA34 702 transcription from Pol I promoter DNA-directed RNA polymerase activity nucleus* S000003684 YKL095W=D <= DIG1=I STE12=I a YKL095W YJU2 837 "nuclear mRNA splicing, via spliceosome" molecular_function unknown nucleus S000001578 YKR013W=D <= DIG1=D STE12=D ab YKR013W PRY2 990 biological_process unknown molecular_function unknown vacuole (sensu Fungi)* S000001721 YML047C=D <= DIG1=D STE12=D b YML047C PRM6 1059 conjugation with cellular fusion molecular_function unknown integral to membrane S000004510 YMR235C=D <= DIG1=D STE12=D a YMR235C RNA1 1224 rRNA-nucleus export* Ran GTPase activator activity nucleus* S000004848 YMR305C=D <= DIG1=D STE12=D ab YMR305C SCW10 1170 conjugation with cellular fusion glucosidase activity cytoplasm* S000004921 YNL053W=D <= DIG1=D STE12=D b YNL053W MSG5 1470 protein amino acid dephosphorylation* prenylated protein tyrosine phosphatase activity cytoplasm S000004998 YNL279W=D <= DIG1=D STE12=D b YNL279W PRM1 1986 plasma membrane fusion molecular_function unknown integral to membrane* S000005223 YNL298W=D <= DIG1=D STE12=D b YNL298W CLA4 2529 protein amino acid phosphorylation* protein serine/threonine kinase activity actin cap S000005242 YOL082W=D <= DIG1=I STE12=I ab YOL082W ATG19 1248 protein-vacuolar targeting protein binding cytoplasm* S000005442 YPL048W=D <= DIG1=D STE12=D ab YPL048W CAM1 1248 regulation of translational elongation translation elongation factor activity cytosolic ribosome (sensu Eukaryota) S000005969 YPL156C=D <= DIG1=I STE12=I a YPL156C PRM4 855 conjugation with cellular fusion molecular_function unknown integral to membrane S000006077 YAP7 FKH1 4 (3) YDR003W=D <= FKH1=I YAP7=I a YDR003W RCR2 633 biological_process unknown molecular_function unknown cytoplasm* S000002410 YHR200W=D <= FKH1=D YAP7=I a YHR200W RPN10 807 ubiquitin-dependent protein catabolism endopeptidase activity proteasome regulatory particle (sensu Eukaryota)* S000001243 YJL100W=D <= FKH1=I YAP7=I a YJL100W LSB6 1824 actin filament organization 1-phosphatidylinositol 4-kinase activity cytoplasm* S000003636 YAP7 CBF1 5 (4) YAL012W=D <= CBF1=D YAP7=D a YAL012W CYS3 1185 sulfur amino acid metabolism* cystathionine gamma-lyase activity cytoplasm S000000010 YAL012W=D <= CBF1=D YAP7=I a YAL012W CYS3 1185 sulfur amino acid metabolism* cystathionine gamma-lyase activity cytoplasm S000000010 YDR055W=D <= CBF1=I YAP7=I b YDR055W PST1 1335 cell wall organization and biogenesis molecular_function unknown cell wall (sensu Fungi) S000002462 YJL100W=D <= CBF1=I YAP7=D a YJL100W LSB6 1824 actin filament organization 1-phosphatidylinositol 4-kinase activity cytoplasm* S000003636 YAP7 NRG1 5 (5) YNL231C=D <= NRG1=D YAP7=D b YNL231C PDR16 1056 response to drug* phosphatidylinositol transporter activity cytoplasm* S000005175 YNR070W=D <= NRG1=D YAP7=D a YNR070W 4002 transport "ATPase activity, coupled to transmembrane movement of substances" mitochondrion* S000005353 YOR226C=D <= NRG1=I YAP7=D ab YOR226C ISU2 471 iron ion homeostasis* molecular_function unknown mitochondrial matrix S000005752 YOR226C=D <= NRG1=I YAP7=I ab YOR226C ISU2 471 iron ion homeostasis* molecular_function unknown mitochondrial matrix S000005752 YOR227W=D <= NRG1=D YAP7=I ab YOR227W 3741 biological_process unknown molecular_function unknown cytoplasm* S000005753 YAP7 MSN4 7 (7) YDL124W=D <= MSN4=D YAP7=I ab YDL124W 939 metabolism alpha-keto amide reductase activity* cytoplasm* S000002282 YHR008C=D <= MSN4=D YAP7=D a YHR008C SOD2 702 replicative cell aging* manganese superoxide dismutase activity mitochondrion* S000001050 YKL101W=D <= MSN4=D YAP7=I c YKL101W HSL1 4557 protein amino acid phosphorylation* protein kinase activity bud neck* S000001584 YMR119W=D <= MSN4=D YAP7=D b YMR119W ASI1 1875 ubiquitin-dependent protein catabolism ubiquitin-protein ligase activity endoplasmic reticulum membrane S000004725 YOR226C=D <= MSN4=D YAP7=I bc YOR226C ISU2 471 iron ion homeostasis* molecular_function unknown mitochondrial matrix S000005752 YOR226C=D <= MSN4=I YAP7=D a YOR226C ISU2 471 iron ion homeostasis* molecular_function unknown mitochondrial matrix S000005752 YOR227W=D <= MSN4=D YAP7=D b YOR227W 3741 biological_process unknown molecular_function unknown cytoplasm* S000005753 YAP7 CIN5 7 (6) YBR008C=D <= CIN5=D YAP7=D a YBR008C FLR1 1647 response to toxin multidrug transporter activity integral to plasma membrane S000000212 YER141W=D <= CIN5=D YAP7=D ab YER141W COX15 1461 cytochrome c oxidase biogenesis* "oxidoreductase activity, acting on NADH or NADPH, heme protein as acceptor" mitochondrial inner membrane S000000943 YER141W=D <= CIN5=D YAP7=I a YER141W COX15 1461 cytochrome c oxidase biogenesis* "oxidoreductase activity, acting on NADH or NADPH, heme protein as acceptor" mitochondrial inner membrane S000000943 YGR209C=D <= CIN5=D YAP7=I ab YGR209C TRX2 315 response to oxidative stress* thiol-disulfide exchange intermediate activity cytosol* S000003441 YKR039W=D <= CIN5=D YAP7=D ab YKR039W GAP1 1809 amino acid transport amino acid permease activity integral to plasma membrane S000001747 YNL134C=D <= CIN5=D YAP7=I abc YNL134C 1131 biological_process unknown alcohol dehydrogenase (NADP+) activity cytoplasm* S000005078 YAP7 GCN4 8 (7) YBR068C=D <= GCN4=D YAP7=D a YBR068C BAP2 1830 amino acid transport amino acid transporter activity plasma membrane S000000272 YBR255W=D <= GCN4=D YAP7=D a YBR255W 2085 biological_process unknown molecular_function unknown cytoplasm S000000459 YER090W=D <= GCN4=D YAP7=D b YER090W TRP2 1524 tryptophan biosynthesis anthranilate synthase activity cytoplasm S000000892 YJR109C=D <= GCN4=D YAP7=D ab YJR109C CPA2 3357 arginine biosynthesis carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity cytosol S000003870 YML116W=D <= GCN4=D YAP7=D ab YML116W ATR1 1629 multidrug transport multidrug efflux pump activity plasma membrane S000004584 YNL239W=D <= GCN4=I YAP7=I b YNL239W LAP3 1365 response to antibiotic transcription regulator activity* cytoplasm* S000005183 YOL058W=D <= GCN4=D YAP7=D ab YOL058W ARG1 1263 arginine biosynthesis* argininosuccinate synthase activity cytosol S000005419 MSN4 GCN4 4 (3) YKL101W=D <= GCN4=I MSN4=I a YKL101W HSL1 4557 protein amino acid phosphorylation* protein kinase activity bud neck* S000001584 YMR251W-A=D <= GCN4=I MSN4=D ab YMR251W-A HOR7 180 response to stress molecular_function unknown endoplasmic reticulum* S000004864 YOL117W=D <= GCN4=D MSN4=I c YOL117W RRI2 1938 adaptation to pheromone during conjugation with cellular fusion* molecular_function unknown signalosome complex S000005477 MSN4 SWI6 4 (3) YER177W=D <= MSN4=D SWI6=D a YER177W BMH1 804 sporulation (sensu Fungi)* protein binding* nucleus S000000979 YOL113W=D <= MSN4=D SWI6=D a YOL113W SKM1 1968 protein amino acid phosphorylation* protein serine/threonine kinase activity cellular_component unknown S000005473 YOL114C=D <= MSN4=D SWI6=I a YOL114C 609 biological_process unknown molecular_function unknown cellular_component unknown S000005474 MSN4 HSF1 7 (6) YAL003W=D <= HSF1=I MSN4=I ab YAL003W EFB1 987 translational elongation translation elongation factor activity ribosome S000000003 YBR072W=D <= HSF1=D MSN4=D ab YBR072W HSP26 645 response to stress* unfolded protein binding cytoplasm* S000000276 YDR155C=D <= HSF1=D MSN4=D b YDR155C CPR1 489 protein metabolism peptidyl-prolyl cis-trans isomerase activity histone deacetylase complex S000002562 YDR171W=D <= HSF1=D MSN4=D abc YDR171W HSP42 1128 response to stress* unfolded protein binding cytoplasm* S000002578 YDR258C=D <= HSF1=D MSN4=D ab YDR258C HSP78 2436 response to stress* ATPase activity* mitochondrial matrix S000002666 YGR192C=D <= HSF1=D MSN4=D b YGR192C TDH3 999 gluconeogenesis* glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) activity cytoplasm* S000003424 MBP1 NRG1 5 (4) YGL012W=D <= MBP1=I NRG1=I a YGL012W ERG4 1422 ergosterol biosynthesis delta24(24-1) sterol reductase activity endoplasmic reticulum S000002980 YMR195W=D <= MBP1=I NRG1=I bc YMR195W ICY1 384 biological_process unknown molecular_function unknown vacuolar membrane (sensu Fungi) S000004808 YPL145C=D <= MBP1=I NRG1=I a YPL145C KES1 1305 vesicle-mediated transport* oxysterol binding cytoplasm* S000006066 YPL230W=D <= MBP1=D NRG1=D a YPL230W 1176 biological_process unknown molecular_function unknown cellular_component unknown S000006151 MBP1 FKH1 6 (5) YDL018C=D <= FKH1=I MBP1=I bc YDL018C ERP3 678 secretory pathway molecular_function unknown integral to membrane S000002176 YDR113C=D <= FKH1=D MBP1=D b YDR113C PDS1 1122 mitotic sister chromatid segregation* protein binding nucleus* S000002520 YMR079W=D <= FKH1=D MBP1=I a YMR079W SEC14 1071 sporulation (sensu Fungi)* phosphatidylinositol transporter activity cytosol S000004684 YNL218W=D <= FKH1=D MBP1=D b YNL218W MGS1 1764 DNA replication* ATPase activity* nucleus S000005162 YNL218W=D <= FKH1=D MBP1=I a YNL218W MGS1 1764 DNA replication* ATPase activity* nucleus S000005162 MBP1 RAP1 6 (6) YGL147C=D <= MBP1=D RAP1=D ab YGL147C RPL9A 576 protein biosynthesis structural constituent of ribosome cytosolic large ribosomal subunit (sensu Eukaryota) S000003115 YGL147C=D <= MBP1=I RAP1=D a YGL147C RPL9A 576 protein biosynthesis structural constituent of ribosome cytosolic large ribosomal subunit (sensu Eukaryota) S000003115 YGR180C=D <= MBP1=D RAP1=D b YGR180C RNR4 1038 DNA replication ribonucleoside-diphosphate reductase activity cytoplasm* S000003412 YLR048W=D <= MBP1=D RAP1=D abc YLR048W RPS0B 1118 protein biosynthesis* structural constituent of ribosome cytosolic small ribosomal subunit (sensu Eukaryota) S000004038 YPL145C=D <= MBP1=D RAP1=D b YPL145C KES1 1305 vesicle-mediated transport* oxysterol binding cytoplasm* S000006066 YPL145C=D <= MBP1=D RAP1=I b YPL145C KES1 1305 vesicle-mediated transport* oxysterol binding cytoplasm* S000006066 MBP1 ABF1 8 (7) YDL105W=D <= ABF1=D MBP1=D b YDL105W QRI2 1209 biological_process unknown molecular_function unknown nucleus S000002263 YLR056W=D <= ABF1=D MBP1=D abc YLR056W ERG3 1098 ergosterol biosynthesis C-5 sterol desaturase activity endoplasmic reticulum S000004046 YNL313C=D <= ABF1=D MBP1=D ab YNL313C 2715 karyogamy molecular_function unknown cytoplasm* S000005257 YNL313C=D <= ABF1=I MBP1=D c YNL313C 2715 karyogamy molecular_function unknown cytoplasm* S000005257 YPR017C=D <= ABF1=D MBP1=D b YPR017C DSS4 432 secretory pathway guanyl-nucleotide exchange factor activity* membrane fraction* S000006221 YPR018W=D <= ABF1=D MBP1=D ab YPR018W RLF2 1821 nucleosome assembly molecular_function unknown nucleus* S000006222 YPR018W=D <= ABF1=I MBP1=I c YPR018W RLF2 1821 nucleosome assembly molecular_function unknown nucleus* S000006222 MBP1 STE12 9 (8) YDR144C=D <= MBP1=D STE12=D ab YDR144C MKC7 1791 proteolysis and peptidolysis aspartic-type signal peptidase activity cell wall (sensu Fungi) S000002551 YFL039C=D <= MBP1=D STE12=D b YFL039C ACT1 1436 cell wall organization and biogenesis* structural constituent of cytoskeleton* actin cortical patch* S000001855 YKR091W=D <= MBP1=I STE12=I ab YKR091W SRL3 741 "nucleobase, nucleoside, nucleotide and nucleic acid metabolism" molecular_function unknown cytoplasm S000001799 YML027W=D <= MBP1=D STE12=D b YML027W YOX1 1158 "negative regulation of transcription from Pol II promoter, mitotic*" DNA binding* nucleus S000004489 YMR305C=D <= MBP1=D STE12=D ab YMR305C SCW10 1170 conjugation with cellular fusion glucosidase activity cytoplasm* S000004921 YNR016C=D <= MBP1=D STE12=D ab YNR016C ACC1 6702 protein-nucleus import* acetyl-CoA carboxylase activity* mitochondrion* S000005299 YOL082W=D <= MBP1=I STE12=I ab YOL082W ATG19 1248 protein-vacuolar targeting protein binding cytoplasm* S000005442 YOR066W=D <= MBP1=D STE12=D b YOR066W 1890 biological_process unknown molecular_function unknown cellular_component unknown S000005592 MBP1 SWI6 18 (16) YBR070C=D <= MBP1=D SWI6=D bc YBR070C 714 biological_process unknown molecular_function unknown nuclear envelope-endoplasmic reticulum network S000000274 YDR263C=D <= MBP1=D SWI6=I a YDR263C DIN7 1293 DNA repair nuclease activity mitochondrion S000002671 YDR507C=D <= MBP1=I SWI6=I c YDR507C GIN4 3429 protein amino acid phosphorylation* protein kinase activity bud neck S000002915 YGL178W=D <= MBP1=D SWI6=I a YGL178W MPT5 3220 cell wall organization and biogenesis* mRNA binding cytoplasm S000003146 YGR109C=D <= MBP1=I SWI6=D c YGR109C CLB6 1143 G1/S transition of mitotic cell cycle* cyclin-dependent protein kinase regulator activity cellular_component unknown S000003341 YGR152C=D <= MBP1=I SWI6=D ac YGR152C RSR1 819 bipolar bud site selection* GTPase activity* plasma membrane* S000003384 YGR180C=D <= MBP1=D SWI6=I b YGR180C RNR4 1038 DNA replication ribonucleoside-diphosphate reductase activity cytoplasm* S000003412 YJL187C=D <= MBP1=D SWI6=D c YJL187C SWE1 2460 G2/M transition of mitotic cell cycle* protein kinase activity nucleus* S000003723 YKL008C=D <= MBP1=D SWI6=D ac YKL008C LAC1 1257 ceramide biosynthesis* sphingosine N-acyltransferase activity endoplasmic reticulum S000001491 YMR179W=D <= MBP1=I SWI6=D c YMR179W SPT21 2277 regulation of transcription from Pol II promoter molecular_function unknown nucleus S000004791 YMR307W=D <= MBP1=I SWI6=D a YMR307W GAS1 1680 cell wall organization and biogenesis "1,3-beta-glucanosyltransferase activity" mitochondrion* S000004924 YNR009W=D <= MBP1=D SWI6=D ac YNR009W 750 biological_process unknown molecular_function unknown cytoplasm* S000005292 YNR009W=D <= MBP1=I SWI6=D a YNR009W 750 biological_process unknown molecular_function unknown cytoplasm* S000005292 YPL127C=D <= MBP1=I SWI6=D c YPL127C HHO1 777 "regulation of transcription, DNA-dependent*" DNA binding nucleus* S000006048 YPR075C=D <= MBP1=D SWI6=D c YPR075C OPY2 1083 cell cycle arrest in response to pheromone molecular_function unknown cytoplasm* S000006279 YPR120C=D <= MBP1=I SWI6=D c YPR120C CLB5 1308 G1/S transition of mitotic cell cycle* cyclin-dependent protein kinase regulator activity nucleus S000006324 UME6 CIN5 4 (4) YCL024W=D <= CIN5=D UME6=I c YCL024W KCC4 3114 protein amino acid phosphorylation* protein kinase activity bud neck S000000529 YCL025C=D <= CIN5=I UME6=D b YCL025C AGP1 1788 amino acid transport amino acid transporter activity plasma membrane S000000530 YLR346C=D <= CIN5=D UME6=I a YLR346C 306 biological_process unknown molecular_function unknown mitochondrion S000004338 YOR177C=D <= CIN5=D UME6=I ab YOR177C MPC54 1395 spore wall assembly (sensu Fungi) structural molecule activity spindle pole body S000005703 UME6 FKH1 5 (5) YHL024W=D <= FKH1=I UME6=I a YHL024W RIM4 2142 meiosis* RNA binding cytoplasm S000001016 YJR091C=D <= FKH1=D UME6=D a YJR091C JSN1 3276 "mRNA catabolism, deadenylylation-dependent decay" mRNA binding cellular_component unknown S000003851 YJR092W=D <= FKH1=D UME6=D bc YJR092W BUD4 4347 bud site selection* GTP binding contractile ring (sensu Saccharomyces) S000003852 YKL038W=D <= FKH1=I UME6=I a YKL038W RGT1 3513 glucose metabolism* DNA binding* nucleus S000001521 YKL217W=D <= FKH1=I UME6=I a YKL217W JEN1 1851 lactate transport lactate transporter activity mitochondrion* S000001700 UME6 CBF1 6 (6) YBR114W=D <= CBF1=I UME6=I ab YBR114W RAD16 2373 "nucleotide-excision repair, DNA damage recognition" DNA-dependent ATPase activity repairosome* S000000318 YHR098C=D <= CBF1=D UME6=D ac YHR098C SFB3 2790 ER to Golgi transport molecular_function unknown endoplasmic reticulum* S000001140 YHR099W=D <= CBF1=I UME6=I a YHR099W TRA1 11235 regulation of transcription from Pol II promoter* histone acetyltransferase activity histone acetyltransferase complex* S000001141 YIL127C=D <= CBF1=D UME6=D ab YIL127C 621 biological_process unknown molecular_function unknown nucleolus S000001389 YJR009C=D <= CBF1=D UME6=D a YJR009C TDH2 999 gluconeogenesis* glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) activity cytoplasm* S000003769 YOL101C=D <= CBF1=I UME6=I ac YOL101C IZH4 939 lipid metabolism* metal ion binding integral to membrane* S000005461 UME6 NRG1 6 (6) YFR015C=D <= NRG1=I UME6=D b YFR015C GSY1 2127 glycogen metabolism glycogen (starch) synthase activity cytoplasm* S000001911 YGR264C=D <= NRG1=I UME6=D ab YGR264C MES1 2256 methionyl-tRNA aminoacylation methionine-tRNA ligase activity cytoplasm* S000003496 YGR266W=D <= NRG1=I UME6=D a YGR266W 2106 biological_process unknown molecular_function unknown mitochondrion* S000003498 YLR012C=D <= NRG1=I UME6=D ab YLR012C 300 biological_process unknown molecular_function unknown cellular_component unknown S000004002 YLR013W=D <= NRG1=D UME6=I a YLR013W GAT3 426 transcription transcription factor activity nucleus S000004003 YOR338W=D <= NRG1=D UME6=I ab YOR338W 1092 biological_process unknown molecular_function unknown cellular_component unknown S000005865 UME6 ABF1 10 (10) YBR283C=D <= ABF1=D UME6=D ab YBR283C SSH1 1473 cotranslational protein-membrane targeting protein transporter activity endoplasmic reticulum membrane* S000000487 YDR285W=D <= ABF1=I UME6=I a YDR285W ZIP1 2628 meiosis* chromatin binding synaptonemal complex S000002693 YGR268C=D <= ABF1=I UME6=I a YGR268C HUA1 597 actin cortical patch assembly molecular_function unknown cytoplasm S000003500 YJR006W=D <= ABF1=D UME6=D a YJR006W HYS2 1464 nucleotide-excision repair* delta DNA polymerase activity delta DNA polymerase complex S000003766 YKL078W=D <= ABF1=D UME6=D ab YKL078W DHR2 2208 ribosome biogenesis RNA helicase activity nucleolus S000001561 YLL046C=D <= ABF1=I UME6=I b YLL046C RNP1 750 ribosome biogenesis and assembly RNA binding cytoplasm S000003969 YLR259C=D <= ABF1=D UME6=D a YLR259C HSP60 1719 protein folding* single-stranded DNA binding mitochondrion S000004249 YMR280C=D <= ABF1=I UME6=I a YMR280C CAT8 4302 positive regulation of transcription from Pol II promoter* specific RNA polymerase II transcription factor activity nucleus S000004893 YOR020C=D <= ABF1=D UME6=D a YOR020C HSP10 321 protein folding unfolded protein binding mitochondrial matrix S000005546 YOR020C=D <= ABF1=I UME6=I b YOR020C HSP10 321 protein folding unfolded protein binding mitochondrial matrix S000005546 FKH1 ABF1 5 (4) YBR029C=D <= ABF1=D FKH1=D ab YBR029C CDS1 1374 phosphatidylglycerol biosynthesis* phosphatidate cytidylyltransferase activity mitochondrion* S000000233 YDL084W=D <= ABF1=D FKH1=D ab YDL084W SUB2 1341 mRNA-nucleus export* protein binding* nucleus* S000002242 YOR310C=D <= ABF1=D FKH1=D ab YOR310C NOP58 1536 rRNA modification* molecular_function unknown small nucleolar ribonucleoprotein complex* S000005837 YOR357C=D <= ABF1=D FKH1=D a YOR357C GRD19 489 protein localization protein binding cytosol S000005884 FKH1 SWI6 7 (5) YDR263C=D <= FKH1=I SWI6=I a YDR263C DIN7 1293 DNA repair nuclease activity mitochondrion S000002671 YJR092W=D <= FKH1=D SWI6=D abc YJR092W BUD4 4347 bud site selection* GTP binding contractile ring (sensu Saccharomyces) S000003852 YMR215W=D <= FKH1=D SWI6=D abc YMR215W GAS3 1575 biological_process unknown "1,3-beta-glucanosyltransferase activity" cell wall (sensu Fungi) S000004828 YOL113W=D <= FKH1=D SWI6=D ac YOL113W SKM1 1968 protein amino acid phosphorylation* protein serine/threonine kinase activity cellular_component unknown S000005473 YPR009W=D <= FKH1=D SWI6=D a YPR009W SUT2 807 regulation of transcription from Pol II promoter* specific RNA polymerase II transcription factor activity nucleus S000006213 FKH1 STE12 8 (6) YAR015W=D <= FKH1=D STE12=D b YAR015W ADE1 921 purine nucleotide biosynthesis* phosphoribosylaminoimidazolesuccinocarboxamide synthase activity cytoplasm* S000000070 YDL240W=D <= FKH1=D STE12=D b YDL240W LRG1 3054 small GTPase mediated signal transduction* Rho GTPase activator activity cytoplasm* S000002399 YDR379W=D <= FKH1=I STE12=I b YDR379W RGA2 3030 actin filament organization* signal transducer activity* intracellular S000002787 YOL031C=D <= FKH1=D STE12=D a YOL031C SIL1 1266 "SRP-dependent cotranslational protein-membrane targeting, translocation" molecular_function unknown endoplasmic reticulum S000005391 YOL031C=D <= FKH1=I STE12=I b YOL031C SIL1 1266 "SRP-dependent cotranslational protein-membrane targeting, translocation" molecular_function unknown endoplasmic reticulum S000005391 YPR075C=D <= FKH1=I STE12=I a YPR075C OPY2 1083 cell cycle arrest in response to pheromone molecular_function unknown cytoplasm* S000006279 CIN5 RAP1 4 (3) YDR300C=D <= CIN5=I RAP1=D ab YDR300C PRO1 1287 proline biosynthesis glutamate 5-kinase activity cytoplasm S000002708 YGR192C=D <= CIN5=D RAP1=I b YGR192C TDH3 999 gluconeogenesis* glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) activity cytoplasm* S000003424 YPR149W=D <= CIN5=D RAP1=I ab YPR149W NCE102 522 protein secretion molecular_function unknown cytoplasm* S000006353 CIN5 CBF1 6 (6) YJR145C=D <= CBF1=D CIN5=I ab YJR145C RPS4A 1042 protein biosynthesis* structural constituent of ribosome cytoplasm* S000003906 YLR081W=D <= CBF1=D CIN5=D b YLR081W GAL2 1725 galactose metabolism* glucose transporter activity* plasma membrane S000004071 YLR081W=D <= CBF1=D CIN5=I b YLR081W GAL2 1725 galactose metabolism* glucose transporter activity* plasma membrane S000004071 YLR081W=D <= CBF1=I CIN5=D a YLR081W GAL2 1725 galactose metabolism* glucose transporter activity* plasma membrane S000004071 YOR230W=D <= CBF1=D CIN5=I a YOR230W WTM1 1314 regulation of meiosis transcription corepressor activity nucleus S000005756 YOR230W=D <= CBF1=I CIN5=D b YOR230W WTM1 1314 regulation of meiosis transcription corepressor activity nucleus S000005756 CIN5 ABF1 6 (4) YGL253W=D <= ABF1=D CIN5=D c YGL253W HXK2 1461 fructose metabolism hexokinase activity nucleus* S000003222 YKL182W=D <= ABF1=D CIN5=D a YKL182W FAS1 6156 fatty acid biosynthesis [acyl-carrier protein] S-malonyltransferase activity* mitochondrion* S000001665 YLR029C=D <= ABF1=D CIN5=D a YLR029C RPL15A 615 protein biosynthesis structural constituent of ribosome* cytosolic large ribosomal subunit (sensu Eukaryota) S000004019 YLR029C=D <= ABF1=D CIN5=I ab YLR029C RPL15A 615 protein biosynthesis structural constituent of ribosome* cytosolic large ribosomal subunit (sensu Eukaryota) S000004019 CIN5 NRG1 10 (8) YBR183W=D <= CIN5=D NRG1=D ab YBR183W YPC1 951 ceramide metabolism ceramidase activity endoplasmic reticulum S000000387 YER028C=D <= CIN5=I NRG1=I b YER028C MIG3 1185 negative regulation of transcription from Pol II promoter* DNA binding* nucleus S000000830 YKL043W=D <= CIN5=D NRG1=D b YKL043W PHD1 1101 pseudohyphal growth specific RNA polymerase II transcription factor activity nucleus S000001526 YKL110C=D <= CIN5=I NRG1=I ab YKL110C KTI12 942 carbon utilization enzyme regulator activity "DNA-directed RNA polymerase II, holoenzyme" S000001593 YMR081C=D <= CIN5=D NRG1=D ab YMR081C ISF1 1017 aerobic respiration molecular_function unknown cellular_component unknown S000004686 YNL217W=D <= CIN5=I NRG1=D b YNL217W 981 biological_process unknown phosphoric monoester hydrolase activity vacuole (sensu Fungi) S000005161 YPR013C=D <= CIN5=D NRG1=D b YPR013C 954 biological_process unknown molecular_function unknown cellular_component unknown S000006217 YPR149W=D <= CIN5=D NRG1=D ab YPR149W NCE102 522 protein secretion molecular_function unknown cytoplasm* S000006353 FHL1 RAP1 65 (65) YBL087C=D <= FHL1=D RAP1=D ab YBL087C RPL23A 918 protein biosynthesis structural constituent of ribosome cytosolic large ribosomal subunit (sensu Eukaryota) S000000183 YBL092W=D <= FHL1=D RAP1=D ab YBL092W RPL32 393 protein biosynthesis structural constituent of ribosome cytosolic large ribosomal subunit (sensu Eukaryota) S000000188 YBR048W=D <= FHL1=D RAP1=D ab YBR048W RPS11B 982 protein biosynthesis* structural constituent of ribosome cytosolic small ribosomal subunit (sensu Eukaryota) S000000252 YBR084C-A=D <= FHL1=D RAP1=D ab YBR084C-A RPL19A 1076 protein biosynthesis structural constituent of ribosome cytosolic large ribosomal subunit (sensu Eukaryota) S000002156 YBR118W=D <= FHL1=D RAP1=D ab YBR118W TEF2 1377 translational elongation translation elongation factor activity ribosome S000000322 YBR189W=D <= FHL1=D RAP1=D ab YBR189W RPS9B 1001 protein biosynthesis* structural constituent of ribosome cytosolic small ribosomal subunit (sensu Eukaryota) S000000393 YBR191W=D <= FHL1=D RAP1=D ab YBR191W RPL21A 871 protein biosynthesis structural constituent of ribosome cytosolic large ribosomal subunit (sensu Eukaryota) S000000395 YCL037C=D <= FHL1=D RAP1=D ab YCL037C SRO9 1305 protein biosynthesis RNA binding polysome S000000542 YDL060W=D <= FHL1=D RAP1=D ab YDL060W TSR1 2367 rRNA processing* ribonucleoprotein binding cytoplasm* S000002218 YDL061C=D <= FHL1=D RAP1=D ab YDL061C RPS29B 171 protein biosynthesis structural constituent of ribosome cytosolic small ribosomal subunit (sensu Eukaryota) S000002219 YDL075W=D <= FHL1=D RAP1=D ab YDL075W RPL31A 763 protein biosynthesis structural constituent of ribosome cytosolic large ribosomal subunit (sensu Eukaryota) S000002233 YDL082W=D <= FHL1=D RAP1=D ab YDL082W RPL13A 965 protein biosynthesis structural constituent of ribosome cytosolic large ribosomal subunit (sensu Eukaryota) S000002240 YDL083C=D <= FHL1=D RAP1=D ab YDL083C RPS16B 864 protein biosynthesis structural constituent of ribosome cytosolic small ribosomal subunit (sensu Eukaryota) S000002241 YDL130W=D <= FHL1=D RAP1=D a YDL130W RPP1B 622 translational elongation* structural constituent of ribosome cytosolic large ribosomal subunit (sensu Eukaryota) S000002288 YDR418W=D <= FHL1=D RAP1=D ab YDR418W RPL12B 498 protein biosynthesis* structural constituent of ribosome cytosolic large ribosomal subunit (sensu Eukaryota) S000002826 YDR450W=D <= FHL1=D RAP1=D ab YDR450W RPS18A 876 protein biosynthesis structural constituent of ribosome mitochondrion* S000002858 YEL054C=D <= FHL1=D RAP1=D ab YEL054C RPL12A 498 protein biosynthesis* structural constituent of ribosome cytosolic large ribosomal subunit (sensu Eukaryota) S000000780 YER074W=D <= FHL1=D RAP1=D ab YER074W RPS24A 874 protein biosynthesis structural constituent of ribosome mitochondrion* S000000876 YER088C=D <= FHL1=I RAP1=I a YER088C DOT6 2013 regulation of transcription from Pol II promoter* molecular_function unknown cytoplasm* S000000890 YER102W=D <= FHL1=D RAP1=D ab YER102W RPS8B 603 protein biosynthesis structural constituent of ribosome cytosolic small ribosomal subunit (sensu Eukaryota) S000000904 YER117W=D <= FHL1=D RAP1=D ab YER117W RPL23B 885 protein biosynthesis structural constituent of ribosome cytosolic large ribosomal subunit (sensu Eukaryota) S000000919 YFR031C-A=D <= FHL1=D RAP1=D ab YFR031C-A RPL2A 912 protein biosynthesis structural constituent of ribosome cytosolic large ribosomal subunit (sensu Eukaryota) S000002104 YGL103W=D <= FHL1=D RAP1=D ab YGL103W RPL28 961 protein biosynthesis structural constituent of ribosome* nucleus* S000003071 YGL104C=D <= FHL1=I RAP1=I ab YGL104C VPS73 1461 protein-vacuolar targeting molecular_function unknown mitochondrion S000003072 YGL123W=D <= FHL1=D RAP1=D ab YGL123W RPS2 765 protein biosynthesis* structural constituent of ribosome cytosolic small ribosomal subunit (sensu Eukaryota) S000003091 YGL135W=D <= FHL1=D RAP1=D ab YGL135W RPL1B 654 protein biosynthesis structural constituent of ribosome cytosolic large ribosomal subunit (sensu Eukaryota) S000003103 YGR034W=D <= FHL1=D RAP1=D ab YGR034W RPL26B 744 protein biosynthesis structural constituent of ribosome* cytosolic large ribosomal subunit (sensu Eukaryota) S000003266 YGR148C=D <= FHL1=D RAP1=D ab YGR148C RPL24B 468 protein biosynthesis structural constituent of ribosome* cytosolic large ribosomal subunit (sensu Eukaryota) S000003380 YGR149W=D <= FHL1=I RAP1=I ab YGR149W 1299 biological_process unknown molecular_function unknown integral to membrane S000003381 YGR213C=D <= FHL1=I RAP1=I b YGR213C RTA1 954 biological_process unknown molecular_function unknown integral to membrane S000003445 YGR214W=D <= FHL1=D RAP1=D ab YGR214W RPS0A 1214 protein biosynthesis* structural constituent of ribosome cytosolic small ribosomal subunit (sensu Eukaryota) S000003446 YHR021C=D <= FHL1=D RAP1=D ab YHR021C RPS27B 799 protein biosynthesis structural constituent of ribosome cytosolic small ribosomal subunit (sensu Eukaryota) S000001063 YHR203C=D <= FHL1=D RAP1=D ab YHR203C RPS4B 1055 protein biosynthesis structural constituent of ribosome cytosolic small ribosomal subunit (sensu Eukaryota) S000001246 YIL018W=D <= FHL1=D RAP1=D ab YIL018W RPL2B 1165 protein biosynthesis structural constituent of ribosome cytosolic large ribosomal subunit (sensu Eukaryota) S000001280 YIL133C=D <= FHL1=D RAP1=D ab YIL133C RPL16A 890 protein biosynthesis structural constituent of ribosome* cytosolic large ribosomal subunit (sensu Eukaryota) S000001395 YIL148W=D <= FHL1=D RAP1=D ab YIL148W RPL40A 821 protein biosynthesis* structural constituent of ribosome cytosolic large ribosomal subunit (sensu Eukaryota) S000001410 YIL149C=D <= FHL1=D RAP1=D ab YIL149C MLP2 5040 protein-nucleus import molecular_function unknown mitochondrion* S000001411 YJL177W=D <= FHL1=D RAP1=D ab YJL177W RPL17B 872 protein biosynthesis structural constituent of ribosome cytosolic large ribosomal subunit (sensu Eukaryota) S000003713 YJR123W=D <= FHL1=D RAP1=D ab YJR123W RPS5 678 protein biosynthesis structural constituent of ribosome cytosolic small ribosomal subunit (sensu Eukaryota) S000003884 YJR145C=D <= FHL1=D RAP1=D ab YJR145C RPS4A 1042 protein biosynthesis* structural constituent of ribosome cytoplasm* S000003906 YKL180W=D <= FHL1=D RAP1=D ab YKL180W RPL17A 861 protein biosynthesis structural constituent of ribosome cytoplasm* S000001663 YLL045C=D <= FHL1=D RAP1=D ab YLL045C RPL8B 771 protein biosynthesis structural constituent of ribosome cytosolic large ribosomal subunit (sensu Eukaryota) S000003968 YLR167W=D <= FHL1=D RAP1=D ab YLR167W RPS31 459 protein biosynthesis* structural constituent of ribosome cytoplasm* S000004157 YLR287C-A=D <= FHL1=D RAP1=D a YLR287C-A RPS30A 622 protein biosynthesis structural constituent of ribosome cytosolic small ribosomal subunit (sensu Eukaryota) S000004278 YLR325C=D <= FHL1=D RAP1=D ab YLR325C RPL38 237 protein biosynthesis structural constituent of ribosome cytosolic large ribosomal subunit (sensu Eukaryota) S000004317 YLR344W=D <= FHL1=D RAP1=D ab YLR344W RPL26A 831 protein biosynthesis structural constituent of ribosome* cytosolic large ribosomal subunit (sensu Eukaryota) S000004336 YLR441C=D <= FHL1=D RAP1=D ab YLR441C RPS1A 768 protein biosynthesis structural constituent of ribosome cytosolic small ribosomal subunit (sensu Eukaryota) S000004433 YLR448W=D <= FHL1=D RAP1=D ab YLR448W RPL6B 915 protein biosynthesis* structural constituent of ribosome* cytosolic large ribosomal subunit (sensu Eukaryota) S000004440 YML024W=D <= FHL1=D RAP1=D ab YML024W RPS17A 809 protein biosynthesis* structural constituent of ribosome cytosolic small ribosomal subunit (sensu Eukaryota)* S000004486 YML026C=D <= FHL1=D RAP1=D ab YML026C RPS18B 842 protein biosynthesis structural constituent of ribosome cytosolic small ribosomal subunit (sensu Eukaryota) S000004488 YML063W=D <= FHL1=D RAP1=D ab YML063W RPS1B 768 protein biosynthesis structural constituent of ribosome cytosolic small ribosomal subunit (sensu Eukaryota) S000004528 YMR116C=D <= FHL1=D RAP1=D ab YMR116C ASC1 1233 biological_process unknown molecular_function unknown cytoplasm S000004722 YMR242C=D <= FHL1=D RAP1=D ab YMR242C RPL20A 973 protein biosynthesis structural constituent of ribosome cytosolic large ribosomal subunit (sensu Eukaryota) S000004855 YNL069C=D <= FHL1=D RAP1=D ab YNL069C RPL16B 1046 protein biosynthesis structural constituent of ribosome* cytosolic large ribosomal subunit (sensu Eukaryota) S000005013 YNL096C=D <= FHL1=D RAP1=D ab YNL096C RPS7B 918 protein biosynthesis structural constituent of ribosome cytosolic small ribosomal subunit (sensu Eukaryota) S000005040 YNL162W=D <= FHL1=D RAP1=D ab YNL162W RPL42A 833 protein biosynthesis structural constituent of ribosome cytosolic large ribosomal subunit (sensu Eukaryota) S000005106 YOL039W=D <= FHL1=D RAP1=D ab YOL039W RPP2A 321 translational elongation* structural constituent of ribosome cytosolic large ribosomal subunit (sensu Eukaryota) S000005399 YOL040C=D <= FHL1=D RAP1=D ab YOL040C RPS15 429 protein biosynthesis* structural constituent of ribosome cytosolic small ribosomal subunit (sensu Eukaryota) S000005400 YOL120C=D <= FHL1=D RAP1=D ab YOL120C RPL18A 1008 protein biosynthesis structural constituent of ribosome cytosolic large ribosomal subunit (sensu Eukaryota) S000005480 YOL121C=D <= FHL1=D RAP1=D ab YOL121C RPS19A 825 protein biosynthesis structural constituent of ribosome cytosolic small ribosomal subunit (sensu Eukaryota) S000005481 YOL127W=D <= FHL1=D RAP1=D ab YOL127W RPL25 843 protein biosynthesis* structural constituent of ribosome* cytosolic large ribosomal subunit (sensu Eukaryota) S000005487 YOR095C=D <= FHL1=D RAP1=D ab YOR095C RKI1 777 pentose-phosphate shunt ribose-5-phosphate isomerase activity cytoplasm* S000005621 YOR312C=D <= FHL1=D RAP1=D ab YOR312C RPL20B 932 protein biosynthesis structural constituent of ribosome cytosolic large ribosomal subunit (sensu Eukaryota) S000005839 YPL090C=D <= FHL1=D RAP1=D ab YPL090C RPS6A 1105 protein biosynthesis structural constituent of ribosome cytosolic small ribosomal subunit (sensu Eukaryota) S000006011 YPR080W=D <= FHL1=D RAP1=D ab YPR080W TEF1 1377 translational elongation translation elongation factor activity ribosome S000006284 SWI6 REB1 4 (4) YJL194W=D <= REB1=I SWI6=I ab YJL194W CDC6 1542 pre-replicative complex formation and maintenance protein binding* pre-replicative complex S000003730 YNR017W=D <= REB1=D SWI6=D a YNR017W MAS6 669 mitochondrial matrix protein import protein transporter activity mitochondrion* S000005300 YOR074C=D <= REB1=I SWI6=I b YOR074C CDC21 915 DNA-dependent DNA replication* thymidylate synthase activity nucleus S000005600 YOR075W=D <= REB1=I SWI6=I b YOR075W UFE1 1041 vesicle fusion* t-SNARE activity endoplasmic reticulum membrane S000005601 SWI6 STE12 9 (4) YML027W=D <= STE12=D SWI6=D c YML027W YOX1 1158 "negative regulation of transcription from Pol II promoter, mitotic*" DNA binding* nucleus S000004489 YMR305C=D <= STE12=D SWI6=D a YMR305C SCW10 1170 conjugation with cellular fusion glucosidase activity cytoplasm* S000004921 YOR247W=D <= STE12=D SWI6=D ac YOR247W SRL1 633 "nucleobase, nucleoside, nucleotide and nucleic acid metabolism" molecular_function unknown cytoplasm* S000005773 YPR075C=D <= STE12=I SWI6=I a YPR075C OPY2 1083 cell cycle arrest in response to pheromone molecular_function unknown cytoplasm* S000006279 CBF1 HSF1 4 (4) YAL012W=D <= CBF1=I HSF1=I a YAL012W CYS3 1185 sulfur amino acid metabolism* cystathionine gamma-lyase activity cytoplasm S000000010 YGL055W=D <= CBF1=D HSF1=D ab YGL055W OLE1 1533 mitochondrion inheritance* stearoyl-CoA 9-desaturase activity endoplasmic reticulum membrane S000003023 YGL056C=D <= CBF1=D HSF1=D a YGL056C SDS23 1584 biological_process unknown molecular_function unknown cytoplasm* S000003024 YPL250C=D <= CBF1=D HSF1=D a YPL250C ICY2 411 biological_process unknown molecular_function unknown cellular_component unknown S000006171 CBF1 REB1 4 (3) YKR069W=D <= CBF1=D REB1=D b YKR069W MET1 1782 methionine metabolism* uroporphyrin-III C-methyltransferase activity cellular_component unknown S000001777 YNL220W=D <= CBF1=D REB1=I b YNL220W ADE12 1302 purine nucleotide biosynthesis* adenylosuccinate synthase activity cytoplasm S000005164 YNR014W=D <= CBF1=I REB1=D b YNR014W 639 biological_process unknown molecular_function unknown cytoplasm S000005297 CBF1 NRG1 5 (4) YDR508C=D <= CBF1=D NRG1=I a YDR508C GNP1 1992 amino acid transport amino acid transporter activity* mitochondrion* S000002916 YDR508C=D <= CBF1=I NRG1=I ab YDR508C GNP1 1992 amino acid transport amino acid transporter activity* mitochondrion* S000002916 YML123C=D <= CBF1=D NRG1=D a YML123C PHO84 1764 phosphate transport* inorganic phosphate transporter activity* integral to plasma membrane S000004592 YPL019C=D <= CBF1=D NRG1=I a YPL019C VTC3 2508 "vacuole fusion, non-autophagic" molecular_function unknown vacuolar membrane S000005940 CBF1 RAP1 7 (5) YJR145C=D <= CBF1=D RAP1=D ab YJR145C RPS4A 1042 protein biosynthesis* structural constituent of ribosome cytoplasm* S000003906 YJR147W=D <= CBF1=D RAP1=I b YJR147W HMS2 1077 pseudohyphal growth molecular_function unknown cytoplasm* S000003908 YOL136C=D <= CBF1=D RAP1=D a YOL136C PFK27 1194 "fructose 2,6-bisphosphate metabolism*" 6-phosphofructo-2-kinase activity cytoplasm S000005496 YPR102C=D <= CBF1=D RAP1=D ab YPR102C RPL11A 525 protein biosynthesis* structural constituent of ribosome cytosolic large ribosomal subunit (sensu Eukaryota) S000006306 YPR103W=D <= CBF1=D RAP1=D a YPR103W PRE2 864 ubiquitin-dependent protein catabolism endopeptidase activity "proteasome core complex, beta-subunit complex (sensu Eukaryota)" S000006307 CBF1 GCN4 9 (9) YBR114W=D <= CBF1=I GCN4=I b YBR114W RAD16 2373 "nucleotide-excision repair, DNA damage recognition" DNA-dependent ATPase activity repairosome* S000000318 YBR249C=D <= CBF1=D GCN4=D b YBR249C ARO4 1113 aromatic amino acid family biosynthesis 3-deoxy-7-phosphoheptulonate synthase activity cytoplasm* S000000453 YBR250W=D <= CBF1=I GCN4=I b YBR250W 1572 biological_process unknown molecular_function unknown cellular_component unknown S000000454 YGR154C=D <= CBF1=D GCN4=D a YGR154C 1071 biological_process unknown molecular_function unknown peroxisome S000003386 YIR017C=D <= CBF1=D GCN4=D ab YIR017C MET28 564 regulation of transcription from Pol II promoter* DNA binding* nucleus S000001456 YIR018W=D <= CBF1=D GCN4=D ab YIR018W YAP5 738 positive regulation of transcription from Pol II promoter RNA polymerase II transcription factor activity nucleus S000001457 YJR145C=D <= CBF1=D GCN4=D b YJR145C RPS4A 1042 protein biosynthesis* structural constituent of ribosome cytoplasm* S000003906 YJR147W=D <= CBF1=I GCN4=I a YJR147W HMS2 1077 pseudohyphal growth molecular_function unknown cytoplasm* S000003908 YLR267W=D <= CBF1=I GCN4=I b YLR267W BOP2 1713 biological_process unknown molecular_function unknown cellular_component unknown S000004257 CBF1 ABF1 9 (7) YDL020C=D <= ABF1=I CBF1=I ab YDL020C RPN4 1596 ubiquitin-dependent protein catabolism* transcriptional activator activity proteasome regulatory particle (sensu Eukaryota)* S000002178 YFL018C=D <= ABF1=D CBF1=D a YFL018C LPD1 1500 acetyl-CoA biosynthesis from pyruvate* dihydrolipoyl dehydrogenase activity pyruvate dehydrogenase complex (sensu Eukaryota)* S000001876 YGR204W=D <= ABF1=D CBF1=D a YGR204W ADE3 2841 purine base biosynthesis* formate-tetrahydrofolate ligase activity* cytoplasm* S000003436 YHR042W=D <= ABF1=D CBF1=D a YHR042W NCP1 2076 ergosterol biosynthesis electron transporter activity mitochondrion* S000001084 YKL008C=D <= ABF1=D CBF1=D ac YKL008C LAC1 1257 ceramide biosynthesis* sphingosine N-acyltransferase activity endoplasmic reticulum S000001491 YMR217W=D <= ABF1=D CBF1=D ab YMR217W GUA1 1578 GMP metabolism GMP synthase (glutamine-hydrolyzing) activity cellular_component unknown S000004830 YOR099W=D <= ABF1=D CBF1=D a YOR099W KTR1 1182 O-linked glycosylation* "alpha-1,2-mannosyltransferase activity" Golgi apparatus S000005625 NRG1 GCN4 4 (3) YER091C=D <= GCN4=I NRG1=D b YER091C MET6 2304 methionine biosynthesis 5-methyltetrahydropteroyltriglutamate-homocysteine S-methyltransferase activity cytoplasm S000000893 YKL051W=D <= GCN4=I NRG1=D b YKL051W SFK1 1062 actin cytoskeleton organization and biogenesis* molecular_function unknown plasma membrane S000001534 YMR251W-A=D <= GCN4=I NRG1=D ab YMR251W-A HOR7 180 response to stress molecular_function unknown endoplasmic reticulum* S000004864 NRG1 RAP1 4 (4) YDR111C=D <= NRG1=I RAP1=D b YDR111C ALT2 1524 biological_process unknown transaminase activity cytoplasm* S000002518 YLR312C=D <= NRG1=D RAP1=I ab YLR312C 1197 biological_process unknown molecular_function unknown cellular_component unknown S000004303 YPL145C=D <= NRG1=I RAP1=D a YPL145C KES1 1305 vesicle-mediated transport* oxysterol binding cytoplasm* S000006066 YPR149W=D <= NRG1=D RAP1=I abc YPR149W NCE102 522 protein secretion molecular_function unknown cytoplasm* S000006353 NRG1 HSF1 10 (4) YBR067C=D <= HSF1=D NRG1=D bc YBR067C TIP1 633 cell wall organization and biogenesis structural constituent of cell wall* cell wall (sensu Fungi) S000000271 YBR067C=D <= HSF1=I NRG1=I a YBR067C TIP1 633 cell wall organization and biogenesis structural constituent of cell wall* cell wall (sensu Fungi) S000000271 YKL051W=D <= HSF1=I NRG1=I a YKL051W SFK1 1062 actin cytoskeleton organization and biogenesis* molecular_function unknown plasma membrane S000001534 YMR251W-A=D <= HSF1=D NRG1=D b YMR251W-A HOR7 180 response to stress molecular_function unknown endoplasmic reticulum* S000004864 HSF1 GCN4 7 (7) YDR258C=D <= GCN4=I HSF1=D ab YDR258C HSP78 2436 response to stress* ATPase activity* mitochondrial matrix S000002666 YGR161C=D <= GCN4=D HSF1=D ac YGR161C RTS3 792 protein amino acid dephosphorylation protein phosphatase type 2A activity cytoplasm* S000003393 YHR162W=D <= GCN4=I HSF1=I a YHR162W 390 biological_process unknown molecular_function unknown mitochondrion S000001205 YKL051W=D <= GCN4=I HSF1=I a YKL051W SFK1 1062 actin cytoskeleton organization and biogenesis* molecular_function unknown plasma membrane S000001534 YMR251W-A=D <= GCN4=I HSF1=D ab YMR251W-A HOR7 180 response to stress molecular_function unknown endoplasmic reticulum* S000004864 YNR069C=D <= GCN4=I HSF1=D a YNR069C BSC5 1470 biological_process unknown molecular_function unknown cellular_component unknown S000005352 YPL250C=D <= GCN4=D HSF1=D c YPL250C ICY2 411 biological_process unknown molecular_function unknown cellular_component unknown S000006171 GCN4 STE12 4 (4) YBR162C=D <= GCN4=D STE12=D ab YBR162C TOS1 1368 biological_process unknown molecular_function unknown cell wall (sensu Fungi)* S000000366 YBR162C=D <= GCN4=I STE12=D a YBR162C TOS1 1368 biological_process unknown molecular_function unknown cell wall (sensu Fungi)* S000000366 YIL117C=D <= GCN4=I STE12=I ab YIL117C PRM5 957 conjugation with cellular fusion molecular_function unknown integral to membrane S000001379 YPR145W=D <= GCN4=I STE12=D a YPR145W ASN1 1719 asparagine biosynthesis asparagine synthase (glutamine-hydrolyzing) activity cytoplasm S000006349 GCN4 RAP1 4 (4) YJR145C=D <= GCN4=D RAP1=D ab YJR145C RPS4A 1042 protein biosynthesis* structural constituent of ribosome cytoplasm* S000003906 YJR145C=D <= GCN4=I RAP1=D a YJR145C RPS4A 1042 protein biosynthesis* structural constituent of ribosome cytoplasm* S000003906 YJR147W=D <= GCN4=D RAP1=D ab YJR147W HMS2 1077 pseudohyphal growth molecular_function unknown cytoplasm* S000003908 YJR147W=D <= GCN4=I RAP1=D a YJR147W HMS2 1077 pseudohyphal growth molecular_function unknown cytoplasm* S000003908 REB1 STE12 4 (4) YJL196C=D <= REB1=D STE12=D a YJL196C ELO1 933 "fatty acid elongation, unsaturated fatty acid" fatty acid elongase activity membrane S000003732 YKL104C=D <= REB1=D STE12=D a YKL104C GFA1 2154 cell wall chitin biosynthesis glutamine-fructose-6-phosphate transaminase (isomerizing) activity cellular_component unknown S000001587 YNR016C=D <= REB1=D STE12=D ab YNR016C ACC1 6702 protein-nucleus import* acetyl-CoA carboxylase activity* mitochondrion* S000005299 YOR093C=D <= REB1=D STE12=D ab YOR093C 4947 biological_process unknown molecular_function unknown cellular_component unknown S000005619 REB1 ABF1 6 (6) YJR137C=D <= ABF1=D REB1=D b YJR137C ECM17 4329 cell wall organization and biogenesis* sulfite reductase (NADPH) activity cytoplasm* S000003898 YJR138W=D <= ABF1=D REB1=D b YJR138W IML1 4755 biological_process unknown molecular_function unknown vacuolar membrane (sensu Fungi) S000003899 YKR069W=D <= ABF1=D REB1=D b YKR069W MET1 1782 methionine metabolism* uroporphyrin-III C-methyltransferase activity cellular_component unknown S000001777 YML081W=D <= ABF1=D REB1=D b YML081W 3756 biological_process unknown molecular_function unknown nucleus S000004546 YNL117W=D <= ABF1=I REB1=I a YNL117W MLS1 1665 glyoxylate cycle malate synthase activity cytoplasm* S000005061 YOR117W=D <= ABF1=I REB1=I b YOR117W RPT5 1305 ubiquitin-dependent protein catabolism ATPase activity* proteasome regulatory particle (sensu Eukaryota)* S000005643 STE12 ABF1 4 (4) YDR312W=D <= ABF1=D STE12=D ac YDR312W SSF2 1362 ribosomal large subunit assembly and maintenance* rRNA binding nucleolus S000002720 YMR197C=D <= ABF1=I STE12=I bc YMR197C VTI1 654 vesicle fusion* v-SNARE activity integral to Golgi membrane S000004810 YMR235C=D <= ABF1=D STE12=D a YMR235C RNA1 1224 rRNA-nucleus export* Ran GTPase activator activity nucleus* S000004848 YPL146C=D <= ABF1=D STE12=D a YPL146C RRP16 1368 biological_process unknown molecular_function unknown nucleus* S000006067