YES

   1: F(G(x1,A(),B())) -> x1
   2: G(F(H(C(),D())),x1,x2) -> H(K1(x1),K2(x2))
   3: K1(A()) -> C()
   4: K2(B()) -> D()

@Rule Labeling
--- R
   1: F(G(x1,A(),B())) -> x1
   2: G(F(H(C(),D())),x1,x2) -> H(K1(x1),K2(x2))
   3: K1(A()) -> C()
   4: K2(B()) -> D()

--- S
   1: F(G(x1,A(),B())) -> x1
   2: G(F(H(C(),D())),x1,x2) -> H(K1(x1),K2(x2))
   3: K1(A()) -> C()
   4: K2(B()) -> D()