Scientists test a novel metric that links cardio-metabolic risk factors in men and women to the built environment

Cardiovascular disease is a leading cause of non-communicable disease burden and death. Population-level interventions targeting modifiable risk factors can reduce disease burden, by enabling people to make daily, healthy choices via long-term structural features. Now, researchers from Japan and Canada test a novel urban design metric based on the space syntax theory that links cardio-metabolic disease risk factors to the built environment, offering opportunities to implement effective population-wide interventions that improve cardio-metabolic outcomes.

Cardiovascular disease is still one of the two leading causes of non-communicable disease burden and death in North America. A growing body of evidence has linked the built environment to cardiovascular disease risk. A tried and tested approach to preventing cardiovascular disease is to target modifiable risk factors, such as physical activity. For instance, effective population-level interventions have immense potential to reduce cardiovascular disease burdens.

Drawing attention to the built environment's influence on cardio-metabolic health is gaining traction, given its well-known positive influence on physical activity. While many studies have investigated this association, generalizations cannot be applied between different countries due to differences in climate, healthcare systems, and culture. Furthermore, while the metrics employed to establish possible links between cardio-metabolic risk factors and the built environment have proven to be suitable for generating predictions, the information generated cannot be easily incorporated into making changes in urban design policy.

In a new study published in Preventive Medicine, a group of researchers led by Associate Professor Mohammad Javad Koohsari from the Japan Advanced Institute of Science and Technology, an adjunct researcher at the Waseda University as well, propose using a new metric, the space syntax walkability index, to address this limitation. Professor Koichiro Oka from Waseda University, Professor Tomoki Nakaya from Tohoku University, and Associate Professor Gavin R. McCormack from the University of Calgary in Canada were also involved in planning and executing the study.

Elaborating on the team's motivation, Dr. Koohsari says, "There is a growing awareness about the impact of urban design on cardio-metabolic health, but most of this work is based on studies in the US. We wanted to explore this relationship in the Canadian context, since findings from different geographical contexts may lack generalizability. While Canada is similar to Western developed countries in terms of its burden of cardio-metabolic risk factors, the interventions needed must account for local nuances."

The research team analyzed data collected from 7,171 participants enrolled in the second wave of Alberta's Tomorrow Project (ATP). These participants lived in urban areas, had provided biological samples (serum, blood, and urine) for cardio-metabolic analyses, and had completed the follow-up health and lifestyle survey. Geographic information systems were then used to calculate two metrics, the traditional walkability index and the space syntax walkability index.

The research group's new urban design metric incorporates space syntax theory. By quantifying the degree of connectivity between streets, the space syntax walkability index represents street integration and describes how well connected a particular street is to others in the area. A highly integrated network requires fewer changes in direction to reach one's destination. "We found that the novel space syntax walkability metric was negatively correlated to systolic and diastolic blood pressure in men. This metric was also associated with less obesity among men and women. This shows that walkability in urban areas is linked to cardio-metabolic risk factors," stresses Dr. Koohsari when expanding on the study's conclusions.

So how can urban designers and planners improve our cities and design better interventions using this data?

Population-wide changes in cardio-metabolic risk factors can be implemented by creating health-supportive built environments, which enable people to easily make daily, healthy choices via long-term structural features. Dr. Koohsari explains, "This novel metric is likely to allow urban designers to identify poorly designed neighborhoods and target these environments for interventions specific to improving the cardio-metabolic risk factors. However, further studies are needed to better understand the relationships between neighborhood built environment and cardio-metabolic risk factors."

Our altered lifestyle patterns and growing urbanization need not necessarily spell doom for our health and wellbeing. Through scientifically informed decision making and health-friendly planning, we can design built environments that support our fitness goals. This study is a right step in that direction.

Figure 1.
Title: Exploring the link between urban design and cardio-metabolic risk factors
Caption: Researchers have used a new metric to show that cardio-metabolic risk factors for men and women are linked to the built environment.
License: CC BY 2.0.
Image Credit: Monkeystyle3000

Figure 2.
Title: Cardiovascular health could be linked to urban design
Caption: Researchers develop a new metric and establish the link between cardio-metabolic risk factors and the built environment.
License: CC BY 2.0.
Image Credit: COD Newsroom

Reference

Funding information
The Alberta's Tomorrow Project is supported by funding from Alberta Health, Alberta Cancer Foundation, Canadian Partnership Against Cancer, and Health Canada. Mohammad Javad Koohsari is supported by JSPS KAKENHI (Grant 23K09701). Gavin R. McCormack is supported by a Canadian Institutes of Health Research Foundations Scheme Grant (FDN-154331). Tomoki Nakaya received funding from the Japan Society for the Promotion of Science (JSPS) Grants-in-Aid for Scientific Research program (Grant 20H00040). Koichiro Oka received support from the JSPS Grants-in-Aid for Scientific Research program (Grant 20H04113).

June 9, 2023